Clinical trials: Lipid
Parenteral Nutrition
Efficacy and Safety of a Fish Oil Containing Lipid Emulsion
The purpose of the study is to compare a fish oil containing lipid emulsion against a medium-chain/long-chain triglyceride (MCT/LCT) lipid emulsion in terms of their efficacy and safety during postoperative parenteral nutrition.
- Trial name
- NCT01176695
- Testing
- fish oil containing lipid emulsion, MCT/LCT containing lipid emulsion
- Where
- 2 sites in China
- Volunteers
- 240 people
- Sponsor
- B. Braun Melsungen AG
Familial Hypobetalipoproteinemia, Familial Hypobetalipoproteinemia - Heterozygous Form
In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects
Rationale. ANGPTL3 has been identified as important regulator of lipolysis as well as a determinant of plasma levels of apolipoprotein B-containing lipoproteins.
- Trial name
- NCT05569928
- Testing
- Administration of deuterated compounds for kinetic study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marcello Arca
Epilepsy, Child, Only
The Effect of Levetiracetam on Lipid Profile in Children
Levetiracetam is a widely prescribed antiseizure medication in epileptic children due to an estimated better safety profile and easy accessibility.
- Conditions
- Epilepsy, Child, Only, Thyroid, Lipid Disorder
- Trial name
- NCT05276271
- Testing
- the blood sample test results
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Ege University
Pediatric HIV, HIV Infections
Equivalence of Boosted Atazanavir Based Regimens and Currently Effective HAART Regimens
The hypothesis for this study is whether a treatment regimen containing Atazanavir in combination with Ritonavir will work as well as other regimens containing a protease inhibitor and/or a Non-nucleoside Reverse Transcriptase…
- Trial name
- NCT00940771
- Testing
- Boosted Atazanavir
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Phoenix Children's Hospital
Type 2 Diabetes
Soccer and Health: Diet and Exercise on Type 2 Diabetes Mellitus
The present study aims to evaluate the impact of a soccer training program lasting 12 weeks in patients with type 2 diabetes mellitus.
- Trial name
- NCT02554643
- Testing
- Diet, Soccer, Running
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer
Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma
Cardiovascular diseases and cancers, the two leading causes of death in Canada, require cholesterol to sustain their progression.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer, Pancreas Cancer, Metastatic Cancer
- Trial name
- NCT04862260
- Testing
- Cholesterol metabolism disruption
- Where
- 2 sites in Canada
- Volunteers
- 3 people
- Sponsor
- CHU de Quebec-Universite Laval
Coronary Artery Disease, Carotid Artery Diseases
Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)
Heart attacks and strokes caused by the unstable atherosclerotic plaques remain the leading cause of death in the United States. Unstable plaques often have more fat than stable plaques.
- Conditions
- Coronary Artery Disease, Carotid Artery Diseases, Atherosclerosis
- Trial name
- NCT01178320
- Testing
- Simvastatin, simvastatin plus extended-release niacin
- Where
- 19 sites in United States, Canada
- Volunteers
- 230 people
- Sponsor
- University of Washington
Cardiovascular Diseases, Inflammation
Dietary Intake of Alpha-linolenic Acid in Elderly
The purpose of this study is to evaluate the antiatherogenic and anti-inflammatory potential of an adequate intake of alpha-linolenic acid in elderly.
- Conditions
- Cardiovascular Diseases, Inflammation, Metabolism Disorder, Lipid
- Trial name
- NCT03025620
- Testing
- Rapeseed oil, Sunflower oil
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease
Atorvastatin Plus Ezetimibe on Coronary Plaque Progression
Atherosclerosis is a progressive disease. Lipid lowering therapy was the standard treatment for patients with coronary artery disease.
- Trial name
- AEPP (NCT01086020)
- Testing
- atorvastatin, atorvastatin plus ezetimibe
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Dyslipidemias, Overweight and Obesity
Dose Response Effects of Pecan Consumption
The bioactive compounds contained in tree nuts have been shown to beneficially affect cardiometabolic health outcomes. Pecans contain more total phenols, sterols, and flavonoids than any other tree nut.
- Conditions
- Dyslipidemias, Overweight and Obesity, Nutrition, Healthy
- Trial name
- NCT05949879
- Testing
- Pecan LOW, Pecan MID, Pecan HIGH
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Fabry Disease
A Study of Agalsidase Alfa Enyzme Replacement Therapy in Chinese Children and Adults With Fabry Disease
Fabry Disease is a rare blood disorder that some people are born with. People with Fabry disease have low levels of an enzyme called alpha-galactosidase A. This enzyme helps to cut down fat-like substances.
- Trial name
- NCT07187440
- Testing
- No intervention
- Where
- 18 sites in China
- Volunteers
- 200 people
- Sponsor
- Takeda
Adrenoleukodystrophy
Randomized Study of Beta Interferon and Thalidomide in Patients With Adrenoleukodystrophy
OBJECTIVES: I. Evaluate the efficacy of interferon beta and thalidomide in male patients with adrenoleukodystrophy who show evidence of brain inflammatory response and are receiving concurrent glyceryl trierucate and glyceryl…
- Trial name
- NCT00004450
- Testing
- glyceryl trierucate, glyceryl trioleate, interferon beta
- Volunteers
- 60 people
- Sponsor
- FDA Office of Orphan Products Development
Overweight or Obesity
Probiotic Influence on Obesity-Related Lipidemia
This study aims to investigate the effects of Bifidobacterium breve BBr60 on key health indicators in overweight and obese adults.
- Trial name
- NCT06305650
- Testing
- Probiotic
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Hypercholesterolemia
A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemia
The purpose of this placebo-controlled, double-blind study is to assess the effect of several doses of CAT-2054 on LDL-C in hypercholesterolemic patients on a stable dose of high-intensity statin, and to evaluate the safety and…
- Trial name
- NCT02608697
- Testing
- CAT-2054, Atorvastatin
- Where
- 34 sites in United States
- Volunteers
- 153 people
- Sponsor
- Catabasis Pharmaceuticals
Schizophrenia, Schizoaffective Disorder
Glucose and Lipid Metabolism on Antipsychotic Medication
This project aims to a) evaluate the effects of selected antipsychotic medications on insulin action in skeletal muscle (glucose disposal), liver (glucose production) and adipose tissue (whole-body lipolysis), b) evaluate the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Type 2 Diabetes Mellitus, Hyperglycemia
- Trial name
- Glulipid (NCT00515723)
- Testing
- risperidone, olanzapine, quetiapine
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Washington University School of Medicine
Infantile GM2 Gangliosidosis (Disorder)
First-in-Human Study of TSHA-101 Gene Therapy for Treatment of Infantile Onset GM2 Gangliosidosis
GM2 gangliosidoses are a group of autosomal recessive neurodegenerative diseases characterized by a deficiency of the Hex A enzyme to catabolize GM2, thereby causing GM2 accumulation within cellular lysosomes.Hex A is composed of…
- Trial name
- NCT04798235
- Testing
- TSHA-101
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Dr. Anupam Sehgal
Hypercholesterolemia, Cardiovascular Disease
Barley Protein and CVD
The Question posed is: Does an barley protein concentrate have health benefits similar to those demonstrated for soy protein foods which would justify the use of the non-fiber components of barley as functional food ingredients?…
- Conditions
- Hypercholesterolemia, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00334308
- Testing
- Barley protein bread or control (casein) bread
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Overweight, Obesity
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic and increasing burden of…
- Conditions
- Overweight, Obesity, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT01608620
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Lipodystrophy
Intraoperative Fluid Management of Liposuction , Cardiometry Versus Rohrich Formula
The aim of the study is to compare the hemodynamic parameters of fluid resuscitation using Rohrich formula to cardiometry guided stroke volume variation in patients undergoing large volume liposuction surgery .
- Trial name
- NCT05402982
- Testing
- Electrical Cardiometry (EC) ICON, Rohrich formula
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahmed Abdel Wahed Ali
Lipid Disorders and Lipid Measurement
The Very Large Database of Lipids
Closer examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly used lipid parameters to phenotypic…
- Trial name
- VLDL (NCT01698489)
- Where
- United States
- Volunteers
- 5,051,467 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University