Clinical trials: Lipid Profile
Heart Failure, Type 2 Diabetes
Comparison of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes
In this proposal,the investigators will examine whether the selectivity of eplerenone for the MR will translate into a better glucose and metabolic profile compare to spironolactone in patients with HF with glucose intolerance or…
- Conditions
- Heart Failure, Type 2 Diabetes, Glucose Intolerance
- Trial name
- SNOW (NCT01586442)
- Testing
- Eplerenone, Spironolactone
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Montreal Heart Institute
AML (Acute Myeloid Leukemia), BMI
Prognostic Impacts of Lipid Profile and BMI in Adult AML
The goal of this observational study is to evaluate the changes in lipid profile parameters (total cholesterol, triglycerides, HDL-C, and LDL-C) in adult AML patients before and after intensive induction chemotherapy.
- Conditions
- AML (Acute Myeloid Leukemia), BMI, Lipid Profile, Induction Chemotherapy
- Trial name
- AML/BMI (NCT07143877)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Female Hypogonadism
Effects of Estrogen Therapy on Lipid Metabolism and Insulin Sensitivity in Hypogonadal Women
This study aims to evaluate the short-term effects of estrogen therapy on lipid metabolism and insulin sensitivity in hypogonadal women.
- Trial name
- NCT07821086
- Testing
- Estrogen
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Khyber Medical University Peshawar
Coronary Disease
In-hospital Initiation of PCSK9 Inhibitor in Patients With Acute Myocardial Infarction
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been shown to improve cardiovascular outcomes when added to conventional statin therapy.
- Trial name
- NCT05184530
- Testing
- Evolocumab 140 MG/ML
- Volunteers
- 7,556 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Weight
A Study of Lifestyle Intervention in Overweight or Obese Women With Early Stage Breast Cancer
The purpose of this study is to test the hypothesis that an intervention of lifestyle modification will positively impact women with breast cancer who are overweight and/or obese.
- Trial name
- NCT02037542
- Testing
- Diet and exercise
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Diabetes Mellitus, Type 2
Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes
Type 2 diabetes mellitus (DM2) is characterized by chronic hyperglycemia, which is a risk factor for comorbidities and death. Although conventional pharmacotherapy is effective, some individuals do not reach the glycemic targets…
- Trial name
- TAUGLIP-DM2 (NCT04874012)
- Testing
- Active comparator Taurine
- Where
- Brazil
- Volunteers
- 94 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Overweight and Obesity
The Effect of Vitamin D Supplementation in Overweight and Obese Pregnant Women
To understand the role of vitamin D supplementation on pregnancy outcomes and metabolic status in overweight and obese pregnant women.
- Trial name
- NCT04841265
- Testing
- Vitamin D3
- Where
- Singapore
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Hyperlipidemia
Comparison of LDL Particle Count With Other Available Lipid Tests
Despite the wide availability of advanced lipoprotein tests, no reference standard exists for Low Density Lipoprotein Cholesterol (LDL-C) due to inherent problems with each of the assays.
- Trial name
- LIPID (NCT02298894)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Scripps Clinic
Metabolic Disease
Husk Fiber Intervention on Metabolic Health of Centrally Obese School Teachers
A group of 120 school teachers (male=60, female=60) was divided into four subgroups for sixteen weeks of an interventional study. One group was kept in control while the other three groups were assigned intervention.
- Trial name
- NCT06188728
- Testing
- effect of 10 gm psyllium husk fiber twice a day, 30 minutes before breakfast and dinner, Effect of life style modification (Diet, Behavior and physical activity), Combined effect of 10 gm Psyllium husk fiber and lifestyle modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Peshawar
Non Alcoholic Steatohepatitis
The Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Non-alcoholic Fatty Liver Disease: A Randomized, Controlled Study
To study the effects of Hesperidin, flaxseed and both together on lipid profile, liver enzymes, inflammatory factors and hepatic fibrosis in patients with Nonalcoholic Steatohepatitis (NASH), 100 patients who referred to…
- Trial name
- NCT03734510
- Testing
- Dietary Supplement: hesperidin and flaxseed, Dietary Supplement: hesperidin, Dietary Supplement: flaxseed
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- National Nutrition and Food Technology Institute
Metabolic Syndrome, Insulin Resistance
Continuous Tart Cherry Juice Supplementation With Metabolic Syndrome Participants
The present study examined the effect of Montmorency tart cherry juice on functional and blood-based cardio-metabolic markers in humans with Metabolic Syndrome.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Hypertension
- Trial name
- NCT03619941
- Testing
- Montmorency Tart Cherry Juice
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Hertfordshire
Hyperlipidaemia, Hyperlipidemia
Nigella Sativa Supplementation in Hyperlipidemia Treatment
Hyperlipidemia is defined as an elevation of plasma cholesterol, lipid, or lipoprotein levels above normal due to abnormal fat metabolism or function, and individuals with hyperlipidemia are approximately twice as likely to…
- Trial name
- NCT06890546
- Testing
- Nigella Sativa Oil capsule, Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul Bilgi University
Schizophrenia
Effects of an Integrated Multimodal Lifestyle Intervention for Management of Violence in Schizophrenia
Total cholesterol levels and other lipids are associated with violence in psychiatric patients. There is a paucity of studies on preventive interventions.
- Trial name
- NCT05229484
- Testing
- an integrated multimodal lifestyle intervention (MLifeI)
- Where
- Taiwan
- Volunteers
- 62 people
- Sponsor
- I-Shou University
Hypercholesterolemia, Hyperlipidemia
PROSPective Evaluation of Fortified Eggs Related to Improvement in The Biomarker Profile for Your Health
The objective of the study is to assess the effect of fortified eggs (compared to a non-egg supplemented diet) and intermittent fasting (IF) (compared to a usual care diet) on biomarker profile at 4 months.
- Conditions
- Hypercholesterolemia, Hyperlipidemia, Vitamin Deficiency, Obesity
- Trial name
- PROSPERITY (NCT04673721)
- Testing
- Fortified eggs, Intermittent fasting, Non-egg supplemented
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Duke University
SARS-CoV2 Infection
LIPId Profile Changes in Inflammatory Conditions Induced by SARS-CORoronavirus-2
In late 2019, a new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of COVID-19 (COronaVIrus Disease-2019) in Hubei Province, China.
- Trial name
- LIPICOR (NCT05113836)
- Testing
- Deep nasopharyngeal swab, Blood sample at D1, D3 and D7
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes Mellitus, Obesity
Vitamin D Status and Lipid Profile in Obese Adults With Type 2 Diabetes
This prospective, single-center, cross-sectional observational study aims to evaluate the association between serum 25-hydroxyvitamin D concentrations and lipid profile parameters among adults with obesity and established type 2…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Dyslipidemia, Vitamin D Deficiency
- Trial name
- VILD-T2D (NCT07729553)
- Volunteers
- 150 people
- Sponsor
- Sinai University
Overweight and Obesity, Dyslipoproteinemia
Effect of Weight Management Programs on Cardiometabolic Risk Profile in Overweight Women
Aim of this prospective randomized study was to evaluate whether a diet with meal replacements can be as effective as a conventional energy-restricted modified diet on weight loss, body composition and cardiometabolic risk…
- Trial name
- FM-01 (NCT03109834)
- Testing
- Meal replacement (MR), Control (C), Verum
- Volunteers
- 105 people
- Sponsor
- Bonn Education Association for Dietetics r.A., Cologne, Germany
Type 2 Diabetes Mellitus, Hypercholesterolemia
Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.
This is a 16-week double-blind, placebo-controlled (for colesevelam hydrochloride (HCl)) study in the type 2 diabetic subjects and pre-diabetic subjects.
- Conditions
- Type 2 Diabetes Mellitus, Hypercholesterolemia, Pre-diabetes
- Trial name
- NCT00570739
- Testing
- Metformin HCl tablets and Colesevelam tablets, Colesevelam
- Where
- 31 sites in United States, Colombia and 2 more
- Volunteers
- 502 people
- Sponsor
- Daiichi Sankyo
Metabolically Unhealty Obese, Dyslipidemia
Effect of a Low-Calorie MCT-Rich Traditional Minangkabau Diet on Obese Individuals
This study aims to investigate the effect of a low-calorie diet rich in medium-chain triglycerides (MCTs) based on traditional Minangkabau foods on metabolic biomarkers in individuals with obesity.
- Conditions
- Metabolically Unhealty Obese, Dyslipidemia, Diabetes (DM), Resistance, Insulin
- Trial name
- NCT07423884
- Testing
- Low-Calorie Diet Rich in Medium-Chain Triglycerides (MCTs) Based on Traditional Minangkabau Foods
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Andalas University
Hypertension
Simvastatin in Patients With Isolated Arterial Hypertension
The purpose of this study is to determine whether combined therapy with simvastatin and hypotensive drugs (ACEI or ARB) may decrease the blood pressure.
- Trial name
- STIPPARE (NCT01017835)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz