Clinical trials: Lipoedema
Cardiovascular Diseases, Metabolic Disease
Vascular Lab Resource (VLR) Biorepository
This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases.
- Conditions
- Cardiovascular Diseases, Metabolic Disease, Peripheral Artery Disease, Carotid Disease
- Trial name
- NCT05628948
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- The Cleveland Clinic
Lipedema
The Effect of Mediterranean Diet on Pain Level and Biochemical Parameters in Women With Lipedema
Objective: To evaluate the effects of a 3-month Mediterranean diet-based intervention on anthropometric and metabolic outcomes, pain and central sensitisation-related symptoms in women with lipedema.
- Trial name
- NCT07853833
- Testing
- Mediterranean Diet-Based Nutritional Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Baskent University
Lipedema, Metabolism
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema
Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid.
- Trial name
- Lipedema (NCT03271034)
- Testing
- Weight loss
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Lipedema
The National Lipedema Study
Lipedema is a chronic condition with a symmetrical accumulation of painful fatty tissue primarily affecting the limbs, sparing hands, feet and trunk.
- Trial name
- NCT05284266
- Testing
- Liposuction early, Liposuction late, Standard conservative treatment
- Where
- Norway
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Lipedema
Proof of Concept, Randomized, and Crossover Study, to Assess the Effectiveness of Two Types of Compression Garments in Lipedema
The goal of this prospective randomized crossover experimental study is to assess the effectiveness and tolerance of circular and flat fabric garments in stabilizing lower-limb volume in lipedema.
- Trial name
- LipeGar (NCT06964828)
- Testing
- Flat-knitted compression garment
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Isabel Forner-Cordero, MD, PhD
Lymphedema, Lymphatic Disorders
Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders
The purpose of this study is to demonstrate the feasibility of near-infrared fluorescence imaging in subjects with acquired or hereditary lymphedema, in subjects with lipidema and other lymphovascular disorders and in normal…
- Conditions
- Lymphedema, Lymphatic Disorders, Lipedema, Vascular Malformation
- Trial name
- NCT00833599
- Testing
- NIRFLI with ICG
- Where
- 3 sites in United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Lipedema
Is The Pain in Lipedema Patients Neuropathic Pain?
Lipedema is a chronic progressive disease characterized by abnormal increase of subcutaneous adipose tissue. It is characterized by bilateral enlargement of the lower and/or upper extremities, typically sparing the hands and…
- Trial name
- NCT05329324
- Testing
- Questionnaire for study group, Questionnaire for control group
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Dokuz Eylul University
Lipedema, Obesity
Microbiota and Lipedema Evaluation in Obese Patient Treated With Very Low Energy Ketogenic Vegan Therapy
Lipedema is a progressive, hereditary, multifactorial disease that occurs primarily in women, characterized by an abnormal and painful accumulation of subcutaneous fatty tissue.
- Conditions
- Lipedema, Obesity, Dysbiosis
- Trial name
- MLVLEKVT (NCT07041684)
- Testing
- Very Low Energy Ketogenic Therapy with vegan meal replacements
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Lipedema
Effectiveness of Kinesio Taping as an Adjunct to Conservative Treatment in Women With Lipedema
This prospective, randomized controlled trial aims to evaluate the effectiveness of kinesio taping as an adjunct to standard conservative treatment in women with stage II lower-extremity lipedema.
- Trial name
- NCT07919574
- Testing
- Kinesio Taping, Standard Conservative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hatice Zehra FERHATLAR
Lipedema
The Effect of Systematic Endurance Training in Treatment of Women With Lipedema
Lipedema is a chronic adipose tissue disorder that primarily affects women. The etiology remains unclear and involves abnormal buildup of fat mainly in the lower limbs.
- Trial name
- LipidEx (NCT06558851)
- Testing
- High intensity endurance training
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Norwegian University of Science and Technology
Lipedema, Hypermobility, Joint
Joint Hypermobility and Associated Factors in Patients With Lipedema
The aim of this observational study is to determine the prevalence of joint hypermobility in female patients with lipedema compared to healthy volunteers.
- Trial name
- LIP-HYP (NCT07808242)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Lipedema
Effects of Exercise in Patients with Lipedema
Lipedema is a chronic progressive disease characterized by symmetrical, disproportionate swelling of subcutaneous adipose tissue, which is common in women and mostly seen in the lower extremities and to a lesser extent in the…
- Trial name
- NCT06811961
- Testing
- Exercise, Physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ilke Keser
Lipedema
Comparison of Triglyceride-Glucose Index and Atherogenic Indices Between Patients With Lipedema and Obese Controls
Women aged 18-75 years with a clinical diagnosis of lipedema and an obese control group will be included in the study. Sociodemographic and clinical data (age, height, weight, medications, etc.) of the participants will be…
- Trial name
- NCT07240298
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lipedema, Exercise Therapy
Investigation of the Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Limb Volume, Functional Capacity, and Quality of Life in Patients With Lipedema
This randomized controlled clinical study aims to investigate and compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), when combined with intermittent pneumatic…
- Conditions
- Lipedema, Exercise Therapy, High Intensity Interval Training
- Trial name
- NCT07319611
- Testing
- Intermittent Pneumatic Compression (IPC), Home-Based Walking Program, High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Marmara University
Aerobic Exercise, Lipedema
Comparison of Different Exercise Protocols for Diagnosed With Lipedema
This study was designed to compare the effects of high-intensity interval training and moderate-intensity continuous training on functional capacity, muscle strength, and quality of life in patients with lipedema, and to…
- Trial name
- NCT07873541
- Testing
- High-Intensity Interval Aerobic Exercise Group, Moderate Intensity Continuous Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hitit University
Lipedema, Pain
Effect of Systemic and Local Ozone Therapy in Lipedema
Lipedema is a disease characterized by enlargement of the subcutaneous tissue and is observed only in the female population. Recently, the inflammatory cascade has been suggested to be the initiator of lipoedema and to play a…
- Conditions
- Lipedema, Pain, Activities of Daily Living, Musculoskeletal Ultrasound
- Trial name
- NCT06954870
- Testing
- Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Williams Syndrome, Lipedema
Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study
Williams syndrome (WS) is a rare microdeletion genetic disorder that has a broad phenotype including many endocrine and metabolic abnormalities. Dr.
- Trial name
- SHAAPE (NCT03758651)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lipedema
Evaluation of Lipoedema Tissue Transcriptome
Lipoedema is a chronic painful disease with a fat distribution disorder affecting women. It is probably aggravated by hormonal changes.
- Trial name
- NCT05861583
- Testing
- fat tissue, lipoedema tissue (stage 1), lipoedema tissue (stage 2)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Lipedema
Serum Maresin-1 Levels in Patients With Lipedema: A Cross-Sectional Study
Lipedema is a chronic and progressive adipose tissue disorder characterized by symmetrical fat accumulation, pain, tenderness, and easy bruising, predominantly affecting women.
- Trial name
- LIP-MARES (NCT07651813)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Lipedema
Aquatic Versus Land-Based Exercise in Women With Lipedema
To evaluate optimal workout environments, a 12-week study assigned women with moderate-to-severe lipedema to three distinct protocols: supervised pool workouts, equivalent land-based training, or basic standard monitoring.
- Trial name
- NCT07756463
- Testing
- aquatic therapy, land- based exercise, usual care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University