Clinical trials: Lipoedema
Lipedema, Knee Osteoarthritis
The Effect of Lipedema on Knee Osteoarthritis
This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context.
- Conditions
- Lipedema, Knee Osteoarthritis, Knee Acute and Chronic Pain, Knee
- Trial name
- NCT07575555
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Izmir Democracy University
Lipedema
Pain, Central Sensitization, and Misophonia in Lipedema
Lipedema is a chronic condition that predominantly affects women and is characterized by disproportionate, usually symmetrical accumulation of subcutaneous fat, particularly in the hips and legs.
- Trial name
- NCT07849634
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Lipedema
Effect of Ketosis on Pain and Quality of Life in Patients With Lipedema
Lipedema is a female progressive fat disorder, characterized by a symmetrical increase in subcutaneous adipose tissue in the lower extremities with the exception of the waist.
- Trial name
- Lipodiet (NCT04632810)
- Testing
- Ketogenic low energy diet, non-ketogenic low energy diet
- Where
- 2 sites in Norway
- Volunteers
- 70 people
- Sponsor
- Helse Nord-Trøndelag HF
Dercum's Disease
A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas
This Phase 2 study will be an open-label and randomized study to assess the efficacy and safety of CBL-514 in participants with Dercum's Disease lipomas.
- Trial name
- NCT05387733
- Testing
- 10 mg CBL-514 per injection, 15 mg CBL-514 per injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Lipedema, Healthy
Muscle Strength, Muscle Endurance, Lower Extremity Function, Aerobic Capacity, Pressure Pain Threshold and Edema in Women With Lipedema
Lipedema is a chronic progressive disease that causes disproportionate, painful extremities with abnormal fat distribution. Lipedema is known to cause physical and psychosocial disorders in individuals, but there are very limited…
- Trial name
- NCT06866847
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Lipedema
The Effects of Endurance Training on Lipedema
Lipedema is a fat disorder causing accumulation of subcutaneous adipose tissue particularly in arms and legs, and predominantly affects women.
- Trial name
- LipidEx (NCT05488977)
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 58 people
- Sponsor
- Norwegian University of Science and Technology
Lipedema
Visualizing Vascular Mechanisms of Lipedema
This work will address clinical unmet needs for patients with lipedema using advanced magnetic resonance imaging (MRI) methods, in sequence with portable clinical tools, by testing fundamental hypotheses regarding potential…
- Trial name
- VMP (NCT05464927)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Vitamin D Deficiency, B12 Deficiency Vitamin
Relationship Between Vitamin D and Vitamin B12 Levels and Neuropathic Pain in Lipedema
Lipedema is a disease characterized by bilateral abnormal fat deposition in the upper and lower extremities. Pain is a common symptom in lipedema.Vitamin D plays an important role in chronic pain.
- Conditions
- Vitamin D Deficiency, B12 Deficiency Vitamin, Lipedema
- Trial name
- NCT06338059
- Testing
- Vitamin B12 Level
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema
Effect of Ultrasound Cavitation Versus Pneumatic Compression on Adipose Tissue Thickness on Lipedema Patients
PURPOSE: This study will be conducted to investigate any significant effect of ultrasound fat cavitation or pneumatic compression on adipose tissue thickness in patients with lipedema.
- Trial name
- NCT07404059
- Testing
- fat cavitation
- Where
- Egypt
- Sponsor
- Cairo University
Central Sensitization, Lipedema
The Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational Study
The aim of this study is to evaluate the effect of metabolic markers (HOMA-IR, triglyceride/HDL ratio, HbA1c, waist and hip circumference measurements, BMI, etc.) on pain and central sensitization in patients diagnosed with…
- Conditions
- Central Sensitization, Lipedema, Pain, HOMA-IR
- Trial name
- NCT07468097
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Marmara University
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lipoedema
A Study to Evaluate the Clinical Benefit and Safety of Medical Compression Garments in the Management of Patients With Lipedema
Lipedema (LI) is a chronic condition, painful disease characterized by a disproportionate increase in adipose tissue and pain in women's legs and sometimes arms.
- Trial name
- LIP'EX (NCT07125092)
- Testing
- compression group
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Thuasne
Lipedema
Vasculera in Participants With Lipedema
This study is designed to gain preliminary information via a uniform protocol regarding the clinical effects of Vasculera in participants with lipedema and the possible role of the glycocalyx as a physiological target for…
- Trial name
- NCT05616962
- Testing
- Diosmiplex
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Primus Pharmaceuticals
Lipedema, Dercum's Disease
Insight Into Subcutaneous Adipose Tissue Disorders
The INSIGHT study aims to phenotype individuals with subcutaneous adipose tissue (SAT) disorders specifically lipedema and Dercum's disease with an aim to find a cure for the SAT in these disorders that is resistant to diet and…
- Conditions
- Lipedema, Dercum's Disease, Familial Multiple Lipomatosis, Madelung's Disease
- Trial name
- INSIGHT (NCT02838277)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Lipedema, Central Sensitisation
Investigation of Central Sensitization and Associated Factors in Patients With Lipedema
This study aims to investigate the presence of central sensitization and its associated parameters in patients with lipedema. Lipedema is a chronic and hereditary condition that primarily affects the lower extremities in women…
- Trial name
- NCT06770634
- Testing
- Pain-Pressure Threshold Measurement With an Algometer, Central Sensitization Inventory, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Lipedema, Obesity & Overweight
Ultrasonographic Evaluation and Pedobarographic Correlation of Lower Extremity Muscles in Lipedema Patients
The primary aim of this study is to evaluate the lower extremity muscle structure, lower extremity alignment, and foot posture in lipedema; secondly, to reveal the chain relationship and biomechanical problems that may be…
- Trial name
- PODUSG (NCT07724483)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lipedema
ESWT for Primary Lipedema
This randomized controlled clinical trial aims to evaluate the effectiveness of extracorporeal shockwave therapy (ESWT) when added to standard conservative treatment in women with primary lipedema.
- Trial name
- ESWT-LIP (NCT07240415)
- Testing
- Standard Conservative Therapy, radial ESWT
- Volunteers
- 50 people
- Sponsor
- Fatih Bagcier
Lipedema, Secondary Lymphedema
Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy
This study is designed to investigate the therapy outcomes from routine physical therapy in persons with lipedema and secondary limb lymphedema.
- Trial name
- NCT03634462
- Testing
- CDT with graded negative pressure
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Lipedema, Obesity, Morbid
Effect of an Low Carbon High Fat Diet on Pain- and Quality of Life in Patients With Lipedema
Lipedema is a chronic disease with unproportional, symmetrical fat accumulation in the lower extremities. Patients experience pain in affected areas, and reduced quality of life.
- Trial name
- LIPODIET (NCT03710798)
- Testing
- Low carbohydrate high fat diet
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Helse Nord-Trøndelag HF
Lipedema
Quadrivas Therapy® to Reduce Lipedema Subcutaneous Adipose Tissue (QUADRIVAS)
Quad Rivas Therapy has been developed by Alyna Eekma from the Netherlands for over thirteen years; anecdotally she has been able to significantly reduce lipedema SAT in women with Stage 1 and 2 lipedema, and can reduce lipedema…
- Trial name
- QUADRIVAS (NCT02907411)
- Testing
- Quadrivas Therapy
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- University of Arizona