Clinical trials: Lithotripsy, Laser
Ureteric Stone
Effectiveness of LASER in Treatment of Ureteric Stones.
Ureteroscopic laser lithotripsy is becoming the most commonly utilized treatment for patients with ureteral stone. The Holmium: YAG laser is integral to the operation and is the preferred flexible intracorporeal lithotripsy.
- Trial name
- LASER (NCT06975488)
- Testing
- LASER Lithotripsy ( Fragmentation modality), LASER lithotripsy (Dusting Modality)
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- District Headquarters Teaching Hospital Sahiwal
Urolithiasis, Nephrolithiasis
Access Sheaths With Aspiration for Renal RetrOgrade Surgery, Randomized CompArative Outcomes
The goal of this clinical trial is to learn whether the ClearPetra ureteral access sheath (Coloplast) is more effective than the Navigator ureteral access sheath (Boston Scientific) in treating intrarenal kidney stones of 1-3 cm…
- Conditions
- Urolithiasis, Nephrolithiasis, Kidney Calculi, Ureteroscopy
- Trial name
- ARROCA01 (NCT07678255)
- Testing
- ClearPetra ureteral access sheath, Navigator ureteral access sheath
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Kidney Calculi
Comparing Super Pulse Fiber Thulium Laser and Holmium Laser for Ureteral Stone Fragmentation During Ureteroscopy
The goal of this prospective, multicenter, randomized controlled trial is to objectively evaluate the clinical efficacy and safety differences between superpulse thulium fiber laser (sTFL) and holmium:YAG laser (Ho:YAG) in…
- Trial name
- NCT06667557
- Testing
- Superpulse Thulium Fiber Laser (sTFL) Treatment, Holmium:YAG Laser (Ho:YAG) Treatment
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Ureteral Stone
Temperature Profiles During Laser Activation in Ureteroscopic Lithotripsy
The primary aim of this study is to investigate the temperature profiles in the renal pelvis during ureteroscopic Thulium Fiber Laser activation using different settings.
- Trial name
- NCT05677425
- Testing
- Temperature measurement
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Haukeland University Hospital
Kidney Stones
Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Management of Renal Stones
This randomized controlled clinical trial evaluated whether furosemide-assisted forced diuresis during flexible ureteroscopy reduced the residual fragment rate and improved stone clearance in patients with renal stones measuring…
- Trial name
- NCT07336485
- Testing
- Furosemide, Standard Care After Flexible Ureteroscopy Without Furosemide
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Renal Stones
Ureteroscopic Lithotripsy for Renal Stones Using a Sheathless Approach or Using a Flexible and Navigable Ureteral Access Sheath (FANS)
The primary aim of the study is to compare stone free rates following ureteroscopic (URS) lithotripsy for renal stones with Thulium Fiber Laser (TFL) using a sheathless approach (low power laser settings) or using a flexible and…
- Trial name
- NCT07741084
- Testing
- Sheathless URS, FANS, low power, FANS, high power
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Haukeland University Hospital
Renal Stones, Renal Calculi > 2 cm
Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones
The investigator will compare between holmium laser setting during miniPCNL for renal stones as regard safety \& efficacy
- Trial name
- miniPCNL (NCT07393178)
- Testing
- mini percutaneous nephrolithotomy
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Choledocholithiasis, Pancreatic Duct Stone
Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones
The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. It will also learn about the safety of the low-wattage holmium laser.
- Trial name
- NCT07418112
- Testing
- Laser lithotripsy with low-wattage holmium laser, Electrohydraulic lithotripsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Ureteric Stone
Laser Lithotripsy for Ureteral Stones
Objectives: To present the outcomes of retrograde and antegrade ureteroscopic laser lithotripsy in the treatment of proximal ureteral stones ranging in size from 10 to 20 millimeters in diameter.
- Trial name
- NCT06465784
- Testing
- Retrograde and Antegrade Ureteroscopic Laser Lithotripsy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mahmoud Helmy El saeed Hussein
Urinary Stone
Differences in Postoperative Symptoms With Four Ureteral Stents
This is a prospective randomized controlled trial designed to assess the differences in postoperative symptoms related to placement of a 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents…
- Trial name
- NCT06083051
- Testing
- 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Tria ureteral stents
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- University of Wisconsin, Madison
Coronary Artery Disease
ROtational Atherectomy, Lithotripsy or LasER for the Treatment of CAlcified STEnosis
Some data exist about the efficacy and safety of rotational atherectomy, intravascular lithotripsy and excimer laser to modify calcified plaques.
- Trial name
- ROLLERCOASTR (NCT04181268)
- Testing
- Percutaneous coronary Intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario La Paz
Choledocholithiasis
Laser Versus Mechanical Lithotripsy of Bile Duct Stones
Very large bile duct stones are difficult to remove. The prefered method involves an endoscopic procedure known as endoscopic retrograde cholangiopancreatography (ERCP)performed using a special side viewing endoscope.
- Trial name
- NCT01759979
- Testing
- Laser and mechanical lithotripsy, Mechanical Lithotripsy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Kidney Stone, Renal Stone
Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE)
The purpose of the study is to compare the effects, good and/or bad, of a treatment for removing kidney stones called the SURE procedure for stone evacuation to the standard treatment using a basket for stone removal.
- Conditions
- Kidney Stone, Renal Stone, Urolithiasis
- Trial name
- NCT04519294
- Testing
- SURE, Standard Ureteroscopy (Basketing)
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- Calyxo, Inc.
Renal Stones
Flexible Ureteroscopy Versus ESWL in the Management of Lower Calyceal Stones
to assess safety, efficacy of Flexible ureteroscopy (FURS) holmium:YAG laser lithotripsy (LL) compared to extracorporeal shockwave lithotripsy (ESWL) in management of lower calyceal stones (LC) stones.
- Trial name
- NCT02658942
- Testing
- Ureteroscopy, Shockwave lithotripsy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pediatric Bladder Stones, Bladder Calculi
Vacuum-Assisted Mini-Percutaneous Versus Transurethral Cystolithotripsy in Pediatric Bladder Stones
This prospective randomized pilot study will compare vacuum-assisted mini-percutaneous cystolithotripsy with standard transurethral cystolithotripsy for the treatment of bladder stones in children.
- Conditions
- Pediatric Bladder Stones, Bladder Calculi, Pediatric Urolithiasis
- Trial name
- VAMPCL-Ped (NCT07614880)
- Testing
- Vacuum-Assisted Mini-Percutaneous Cystolithotripsy, Transurethral Cystolithotripsy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Kidney Stone, Ureteral Stone
Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off
The purpose of this study is to compare Moses 2.0 pulse modulation technology and the standard high powered Holmium Laser lithotripsy and how it will affect time in the operating room, time using the laser, laser energy, and…
- Trial name
- NCT06346483
- Testing
- Dusting without Moses 2.0 Modulation, Dusting with Moses 2.0 Modulation, Moses 2.0 Modulation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University
Lithotripsy, Laser
TELAXMAN - Laser Lithotripsy With Automatic Real-time Stone Recognition
Urolithiasis is an extremely common disease affecting about 12% of the world population with increasing tendency. Urinary stones are sediments that form in the kidney from crystals, such as calcium oxalate.
- Trial name
- NCT05500534
- Testing
- Laser lithotripsy with stone recognition, Laser lithortripsy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- LISA Laser Products GmbH
Common Bile Duct Stones
Randomized Trial for Extraction of Difficult Bile Duct Stones
Removal of bile duct stones can be challenging at ERCP, particularly, when the size of the stone is at least 1.2cm, and may require more than one ERCP session.
- Trial name
- NCT00852072
- Testing
- Single-operator cholangioscopy-guided laser lithotripsy, Balloon Sphincteroplasty
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- AdventHealth
Non-stented Ureteroscopic Laser Lithotripsy for Ureteric Stones
Effect of Perioperative Selective alpha1-blockers in Non-stented Ureteroscopic Laser Lithotripsy for Ureteric Stones: A Randomized Controlled Trial
To assess the efficacy of peri-operative alpha1 blockers on improving the success rate and decreasing complications of non-stented ureteroscopic laser lithotripsy for ureteric stones.
- Trial name
- NCT04557202
- Testing
- Tamsulosin Oral Capsule
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Kidney Stones, Urolithiasis
ILY Robotic System vs Manual Flexible Ureteroscopy for Kidney Stone Treatment
The goal of this clinical trial is to compare the efficacy, ergonomics, and safety of robotic versus manual flexible ureteroscopy (fURS) for kidney stone treatment in adult patients undergoing laser lithotripsy.
- Trial name
- iFURS (NCT06996587)
- Testing
- Robotic-Assisted Flexible Ureteroscopy, Manual Flexible Ureteroscopy
- Where
- Lebanon
- Volunteers
- 152 people
- Sponsor
- Albert El Hajj