Clinical trials: Liver Tumour
Liver Metastases, Tumor
End Hole vs. Pressure-Modulated Delivery of Y-90 Resin Microspheres to Liver Metastases.
Patients with liver metastases undergoing planning arteriography for Y-90 administration by interventional radiology will be screened for study enrollment.
- Trial name
- NCT07791446
- Testing
- The TriNav Infusion Systems, Standard End Hole Microcatheter
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Stanford University
Hepatocellular Carcinoma
Effects of Anesthetic Methods on Hepatic Cancer Cell Malignancy
Numerous studies found that anesthetic methods can influence the recurrence of tumor and the overall survival of patients after primary cancer surgery.
- Trial name
- NCT03594188
- Testing
- anesthetic methods
- Where
- China
- Volunteers
- 24 people
- Sponsor
- RenJi Hospital
Colon Cancer Liver Metastasis
Oxaliplatin and Raltitrexed Treatment of Colorectal Cancer With Liver Metastases
The purpose of this study was a randomized controlled trial to compare the effect of oxaliplatin and raltitrexed treatment of colorectal cancer with liver metastases by TACE hepatic artery infusion
- Trial name
- NCT02557490
- Testing
- oxaliplatin and raltitrexed
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhu Xu
Hepatocellular Carcinoma
Lipiodol-TACE With Idarubicin Based On a Specific Emulsion Ratio for Hepatocellular Carcinoma
The purpose of this observational study is to evaluate properties of lipiodol-idarubicin emulsion mixed with the best regimen obtained in vitro study, including stability, viscosity，visibility under X-ray and deposition, in order…
- Trial name
- NCT05631613
- Testing
- cTACE(conventional transarterial chemoembolization)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongda Hospital
Anal Cancer, Carcinoma of the Appendix
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Anal Cancer, Carcinoma of the Appendix, Colorectal Cancer, Esophageal Cancer
- Trial name
- NCT00654160
- Testing
- fluorouracil, irinotecan hydrochloride, leucovorin calcium
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Hepatocellular Carcinoma Stage III
Image Driven Hepatocellular Carcinoma Invasiveness Evaluation Research
Hepatocellular carcinoma (HCC) is a highly heterogeneous malignant tumor with significant differences in invasion, proliferation ability and patient prognosis.
- Trial name
- NCT06559761
- Testing
- Hepatectomy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Liposomal Doxorubicin in Treating Patients With Liver or Bile Duct Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of liposomal doxorubicin in treating patients with liver…
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
- Trial name
- NCT00003296
- Testing
- filgrastim, pegylated liposomal doxorubicin hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Brown University
Hepatocellular Carcinoma
Axitinib as Second-line Treatment for Advanced Hepatocellular Carcinoma
This is a phase II study of axitinib as the second-line on the treatment of advanced hepatocellular carcinoma (HCC). The purpose of this study is a proof-of-concept study to see if axitinib has any anti-tumor effect in HCC.
- Trial name
- NCT01273662
- Testing
- AG-013736
- Where
- 3 sites in Taiwan
- Volunteers
- 45 people
- Sponsor
- National Taiwan University Hospital
Hepatocellular Carcinoma, Recurrent Cancer
Cabozantinib to Treat Recurrent Liver Cancer Post Transplant
This is a phase 2 study that will assess the investigational drug, cabozantinib, in patients with liver cancer (specifically hepatocellular carcinoma) and who had received a liver transplant as a part of curative care, but the…
- Conditions
- Hepatocellular Carcinoma, Recurrent Cancer, Liver Transplant
- Trial name
- NCT04204850
- Testing
- Cabozantinib
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
KRAS Gene, Colorectal Cancer
To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation
To investigate the clinical effect of radiofrequency ablation on colorectal cancer liver metastases with different KRAS gene status
- Conditions
- KRAS Gene, Colorectal Cancer, Liver Metastasis, Safe Margin
- Trial name
- NCT04417010
- Testing
- Radiofrequency ablation
- Volunteers
- 163 people
- Sponsor
- Peking University Cancer Hospital & Institute
Hepatocellular Carcinoma
Laparoscopic Surgery VS RFA for Recurrent HCC
Management of recurrent HCC is urgent and several treatments have been developed .Repeat hepatectomy is considered to be the first choice for recurrent HCC.
- Trial name
- NCT02785380
- Testing
- laparoscopic surgery(LS), RFA
- Volunteers
- 340 people
- Sponsor
- Sun Yat-sen University
Hepatocellular Carcinoma and Liver Disease
HELIO Liver Test Performance Study in China (HEPATIC)
De-identified whole blood and serum samples are collected for the purpose of evaluating the performance (sensitivity/specificity) of the HelioLiver Test for the detection of hepatocellular carcinoma (HCC).
- Trial name
- HEPATIC (NCT05053412)
- Testing
- Helio Liver Test
- Where
- 2 sites in China
- Volunteers
- 1,556 people
- Sponsor
- Helio Genomics
Carcinoma, Hepatocellular
ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma
Open-label, uncontrolled, Phase 1-2 study to evaluate the safety, tolerability, pharmacodynamic effects, and preliminary efficacy of ABX196 administered in combination with nivolumab in patients with hepatocellular carcinoma
- Trial name
- NCT03897543
- Testing
- ABX196
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Abivax S.A.
Hepatocellular Carcinoma
Single Centre Prospective Evaluation of 68Gallium-FAPI PET/MRI in Hepatocellular Carcinoma
Single centre prospective evaluation of 68Gallium(Ga68)-FAPI-46 PET/MRI in patients diagnosed with Hepatocellular Carcinoma (HCC).
- Trial name
- NCT05687747
- Testing
- Radiolabelled tracer, 68Gallium-FAPI-46 PET/MRI
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Hepatocellular Carcinoma
Study of Sorafenib In Combination With Low-dose 5-fluorouracil/Cisplatin (FP) Intraarterial Infusion Chemotherapy
The purpose of this study is to determine the recommended dose of the combination therapy of sorafenib with hepatic arterial infusion of low dose cisplatin and fluorouracil on patients with advanced hepatocellular carcinoma…
- Trial name
- SILIUS (NCT00933816)
- Testing
- sorafenib, cisplatin, fluorouracil
- Where
- 3 sites in Japan
- Volunteers
- 37 people
- Sponsor
- Kindai University
Carcinoma, Hepatocellular
Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads Vs. IV Doxorubicin in Treating Liver Cancer
MTC-DOX is Doxorubicin or DOX, a chemotherapy drug, that is adsorbed, or made to "stick", to magnetic beads (MTCs). MTCs are tiny, microscopic particles of iron and carbon.
- Trial name
- NCT00034333
- Testing
- MTC-DOX for Injection
- Where
- 29 sites in United States, Austria and 6 more
- Volunteers
- 240 people
- Sponsor
- FeRx
Liver Diseases, Hepatocellular Cancer
A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation
Living donor liver transplantation (LDLT), involves complex systems and processes of care that are particularly vulnerable to medical errors and preventable complications.
- Conditions
- Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis
- Trial name
- NCT02073435
- Testing
- Donor pain management
- Where
- 4 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Colon Adenocarcinoma, Rectal Adenocarcinoma
Evaluating Novel Therapies in ctDNA Positive GI Cancers
This study is a non-randomized, open-label, multi-cohort, multi-site, pilot feasibility therapeutic trial. The study will enroll 20 patients across 4 cohorts (CRC, gastric, PDAC, and HCC/intra-hepatic-/extra-hepatic-, gall…
- Conditions
- Colon Adenocarcinoma, Rectal Adenocarcinoma, Gastric Adenocarcinoma, Pancreatic Adenocarcinoma
- Trial name
- MRD-GI (NCT05482516)
- Testing
- Atezolizumab, Bevacizumab
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Georgetown University
Palliative Care, Cancer Liver
Early Palliative Care Integration in Interventional Cancer Care
A mixed methods randomized control trial assessing the impact of early palliative care incorporation in liver cancer and metastatic colorectal cancer on caregiver well-being, patient physical and psychosocial outcomes, and health…
- Conditions
- Palliative Care, Cancer Liver, Cancer Colon
- Trial name
- EPIICC (NCT03185416)
- Testing
- Palliative Care Training
- Sponsor
- University of Miami
Colon Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma
Characterization of Mechanical Tissue Properties in Patients With Pancreatic, Liver, or Colon Cancer
This pilot research trial studies characterization of mechanical tissue properties in patients with pancreatic, liver, or colon cancer.
- Conditions
- Colon Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma, Pancreatic Carcinoma
- Trial name
- NCT03137706
- Testing
- Biospecimen Collection, Laboratory Biomarker Analysis, Laboratory Procedure
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Southern California
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