Clinical trials: Living Kidney Donation
HIV Infections
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
- Trial name
- NCT03408106
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Chronic Kidney Disease, End-Stage Renal Disease
Increasing Kidney Transplant Among Blacks on the Transplant Waiting List
For most patients with kidney failure, living donor kidney transplant (LDKT) is their best treatment option. Unfortunately, Blacks (vs. non-Blacks) are more likely to have kidney failure but less likely to receive LDKTs.
- Trial name
- NCT02319447
- Testing
- Additional education
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- St. Barnabas Medical Center
Living Donor Nephrectomy
Scrotal Surgery After Laparoscopic Donor Nephrectomy
This study will examine whether laparoscopic nephrectomy is associated with a higher long-term risk of receiving scrotal surgery in male living kidney donors compared to male nondonors from the general population who have similar…
- Trial name
- NCT06716723
- Testing
- Nephrectomy
- Where
- Canada
- Volunteers
- 9,878 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Living Kidney Donation
The Living Kidney Donor Safety Study
The main goal of this study is to understand the long-term effects of kidney donation on blood pressure, kidney function, and patient-reported health-related quality of life.
- Trial name
- LKD (NCT00936078)
- Where
- 13 sites in Australia, Canada
- Volunteers
- 1,438 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Transplant, Kidney Donor
Transforming Curiosity Into Donation
This is a multi-step study that will first create a preliminary living donor drop-out risk index (LD-DROP) by retrospectively identifying factors that contribute to the discontinuation of living donor evaluation.
- Conditions
- Kidney Transplant, Kidney Donor, Drop Out, High Risk
- Trial name
- NCT07793890
- Testing
- Living Kidney Donor Support
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Addison Disease, Hypoaldosteronism
Adrenal Function After Living Kidney Donation
The success of kidney transplantation is hampered by the shortage of organs. One attractive strategy is the use of kidneys from living donors.
- Trial name
- NCT00251836
- Testing
- Laparoscopic hand-assisted donor nephrectomy
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Living Donors, Nephrectomy
Conventional Laparoscopic Versus Laparoendoscopic Single Site Donor Nephrectomy in Living Donor Kidney Transplantation
Laparoscopic nephrectomy (removal of the kidney) is the most common procedure for people donating a kidney to be used for living donor kidney transplantation.
- Conditions
- Living Donors, Nephrectomy, Kidney Transplantation, Surgery, Laparoscopic
- Trial name
- NCT01236326
- Testing
- Laparoendoscopic single site donor nephrectomy, Conventional laparoscopic donor nephrectomy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Weill Medical College of Cornell University
Kidney Failure, Surgery
Effect of Lost Wage Reimbursement to Kidney Donors on Living Donation Rates
The study is designed as a randomized controlled trial. The investigators hypothesize that kidney transplant recipient candidates whose donors are offered reimbursement of lost wages (treatment arm) will have a higher probability…
- Conditions
- Kidney Failure, Surgery, Renal Failure
- Trial name
- NCT03350269
- Testing
- Information provision
- Where
- 6 sites in United States
- Volunteers
- 1,310 people
- Sponsor
- Arbor Research Collaborative for Health
Infection
Prophylaxis Of Wound Infections- Antibiotics in Renal Donation
The aim of this study is to see whether antibiotics given at the start of laparoscopic kidney donation surgery prevent infection.
- Trial name
- POWAR (NCT02089568)
- Testing
- Co-Amoxiclav, Normal Saline
- Where
- United Kingdom
- Volunteers
- 284 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Chronic Kidney Diseases, Apolipoprotein L1
APOL1 Genetic Testing Program for Living Donors
Living donor (LD) kidney transplantation is the optimal treatment for patients with end-stage kidney disease (ESKD). However, LDs take on a higher risk of future ESKD themselves.
- Conditions
- Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
- Trial name
- NCT04910867
- Testing
- Components of Genetic Counseling, APOL1 genetic testing, EHR integration
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Northwestern University
Living Kidney Donation
eHealth Usability in Living Kidney Donation
Several web portals for patients are available, but an assessment of their performance is scarce. This is of particular interest among candidates for kidney living donation.
- Trial name
- NCT04791670
- Testing
- survey study
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
ESRD
A Culturally Targeted Transplant Program
Hispanic/Latino patients with end-stage renal disease are disproportionately less likely to get a kidney transplant, and specifically, a living donor kidney transplant (LDKT), compared to non-Hispanic whites.
- Trial name
- HKTP (NCT03276390)
- Testing
- Hispanic Kidney Transplant Program (HKTP)
- Where
- 4 sites in United States
- Volunteers
- 11,836 people
- Sponsor
- Northwestern University
Living Kidney Donation, Preoperative Anxiety
Preoperative Psychotherapy and Its Effects on Anxiety, Hemodynamics, and Pain in Living Kidney Donors
Chronic kidney failure is a condition in which the kidneys progressively lose their ability to filter waste, maintain fluid and electrolyte balance, and support essential physiological functions.
- Conditions
- Living Kidney Donation, Preoperative Anxiety, Postoperative Pain
- Trial name
- PREPSY-KD (NCT07261917)
- Testing
- Preoperative Psychiatric Consultation, No Intervention: Standard Preoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Nephrectomy,Kidney Donation
A Comparison of Kidney Function After Nephrectomy in Living Donors Under Sevoflurane and Desflurane Anesthesia
Living-donor kidney transplantation has been considered as the best treatment for patients with end-stage renal disease (ESRD). Kidney donation from living donors has been performed widely under their noble humanity and a belief…
- Trial name
- NCT01549990
- Testing
- Sevoflurane, desflurane
- Where
- South Korea
- Volunteers
- 236 people
- Sponsor
- Yonsei University
Chronic Pain, Living Kidney Donor
The Effect of Quadratus Lumborum (QL) Block on the Incidence of Chronic Neuropathic Pain After Retroperitoneal Laparoscopic Donor Nephrectomy: A Study on Neuroinflammation and Neurophysiology
To analyze the relationship of anterior subcostal quadratus lumborum (QL) block compared with control block on the incidence of chronic neuropathic pain at three months post-laparoscopic retroperitoneal living kidney donor.
- Conditions
- Chronic Pain, Living Kidney Donor, Quadratus Lumborum Block, Laparoscopic Donor Nephrectomy
- Trial name
- NCT07037992
- Testing
- injection of local anesthesia solution, Injection of normal saline
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Kidney Disease, Chronic, Myocardial Dysfunction
Coronary Microvascular Dysfunction in Chronic Kidney Disease
This is an observational study assessing coronary microvascular function in healthy controls with normal kidney function, living kidney donors, pre-dialysis patients with chronic kidney disease stage 5 and patients on peritoneal…
- Trial name
- CRIB-FLOW (NCT04014127)
- Testing
- Coronary flow reserve assessment, Sphygmocor, Electrocardiogram
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Kidney Transplantation, Rituximab (RTx)
Impact of Rituximab (RTx) Induction and Living Donation on Immunoregulation and Virus Control in Renal Transplantation
This project comprises immunological and virological analyses within a prospective clinical study of Rituximab (Rtx)-treated blood group incompatible living donor (LD) renal transplant recipients compared to blood group…
- Conditions
- Kidney Transplantation, Rituximab (RTx), Living Donors, Immunology
- Trial name
- NCT01136395
- Testing
- Rituximab, living donor transplantation, deceased donor transplantation
- Where
- Germany
- Volunteers
- 85 people
- Sponsor
- University of Giessen
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
By means of a prospective, randomised trial the investigators want to examine skin closure in living donors - subjected to laparoscopic, hand-assisted nephrectomy - by tissue glue (Cyanoacrylate (Liquiband)) versus conventional…
- Trial name
- TG-CYANO (NCT01521871)
- Testing
- Skin wound closure by tissue glue, Skin wound closure by conventional suture + dressing
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
Kidney Transplant
Knowledge and Attitude of Dialysis Center Medical Staff Towards Living Kidney Donation
The goal of this cross-sectional study is to learn about the level of knowledge and attitudes of medical staff working in dialysis centers about living kidney donations.
- Trial name
- NCT05797337
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Kidney Transplant Candidates
Increasing Communication About Live Donor Kidney Transplant
This study will test the efficacy of a communication intervention intended to increase and improve kidney transplant candidates' communication about live donor kidney transplantation.
- Trial name
- NCT01855438
- Testing
- Living Donor Transplant Education
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Virginia Commonwealth University