Clinical trials: Living Kidney Donation, active
Living Kidney Donor, Living Kidney Donation
Fracture Risk in Living Kidney Donors
This study will be a population-based, matched retrospective cohort study using linked administrative healthcare databases from Ontario, Alberta, and British Columbia to evaluate the long-term risk of fractures among living…
- Conditions
- Living Kidney Donor, Living Kidney Donation, Fractures, Nephrectomy,Kidney Donation
- Trial name
- NCT07401953
- Testing
- Nephrectomy
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Living Kidney Donation, Living Kidney Donor
Long-Term Risk of Gout in Living Kidney Donors
This population-based, matched, retrospective cohort study will evaluate the long-term risk of gout among living kidney donors compared with matched healthy nondonors, using linked administrative health care databases from…
- Conditions
- Living Kidney Donation, Living Kidney Donor, Gout, Gout and Hyperuricemia
- Trial name
- NCT07546643
- Testing
- Living kidney donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Living Kidney Donation, Hypertension
Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
The goal of this observational study is to learn if PRAT thickness is a marker of visceral obesity and its influence on donors' kidney function and blood pressure in living kidney donors.
- Conditions
- Living Kidney Donation, Hypertension, Nephrectomy
- Trial name
- ProActive (NCT06886087)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Pain, Living Kidney Donor
The Effect of Quadratus Lumborum (QL) Block on the Incidence of Chronic Neuropathic Pain After Retroperitoneal Laparoscopic Donor Nephrectomy: A Study on Neuroinflammation and Neurophysiology
To analyze the relationship of anterior subcostal quadratus lumborum (QL) block compared with control block on the incidence of chronic neuropathic pain at three months post-laparoscopic retroperitoneal living kidney donor.
- Conditions
- Chronic Pain, Living Kidney Donor, Quadratus Lumborum Block, Laparoscopic Donor Nephrectomy
- Trial name
- NCT07037992
- Testing
- injection of local anesthesia solution, Injection of normal saline
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Kidney Transplantation, Nephrectomy,Kidney Donation
A Qualitative Study on Gratitude and Recognition Toward Living Kidney Donors
Kidney transplantation is widely recognized as the best treatment for patients with end-stage renal disease. However, its development is limited by the persistent shortage of available organs.
- Trial name
- GRACE (NCT07254546)
- Testing
- Semi-structured qualitative interview
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
End Stage Renal Disease, End Stage Liver Disease
Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors
This study utilizes a web-based application to help patients on the organ transplant waitlist communicate patient's need for a living donor via social media and provide interested potential donors the opportunity to engage with…
- Trial name
- NCT03803423
- Testing
- The Donor App
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Living Donor Nephrectomy, Living Kidney Donation
Long-term Risk of Cardiovascular Disease in Living Kidney Donors
The investigative team will conduct a population-based, matched retrospective cohort study across Ontario, Alberta, and British Columbia using linked administrative healthcare databases to evaluate the long-term risk of major…
- Conditions
- Living Donor Nephrectomy, Living Kidney Donation, Living Kidney Donor, Living Kidney Donors
- Trial name
- NCT07431515
- Testing
- Nephrectomy
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Renal Insufficiency, Chronic
Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation.
The selection of kidneys from living donors is based on strict glomerular filtration rate (GFR) values, in the setting of the increasing proportion of older donors.
- Trial name
- DOVIMIR (NCT06047106)
- Testing
- multiparametric MRI, kidney graft biopsy, blood samples
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Kidney Stones, Urolithiasis, Hypocitraturia, Living Kidney Donation
Long-Term Risk of Kidney Stones in Living Kidney Donors
Using a population-based, matched, retrospective cohort approach, this study will evaluate the long-term risk of kidney stones among living kidney donors compared with matched healthy nondonors.
- Conditions
- Kidney Stones, Urolithiasis, Hypocitraturia, Living Kidney Donation, Living Kidney Donor
- Trial name
- NCT07611500
- Testing
- Living kidney donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Diseases
Promoting Increases in Living Donation Via Tele-navigation (PILOT)
We hypothesize that expansion of the Living Donor Navigator (LDN) program to include tele-health delivery will overcome geographic disparities in access and facilitate sustained increases in living donation.
- Trial name
- PILOT (NCT05468463)
- Testing
- Living Donor Navigator Program
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- University of Alabama at Birmingham
Transplant Donation
Information-Assisted Intervention for Potential Living Kidney Donors
This study aims to evaluate the effectiveness of an information-assisted intervention in enhancing knowledge, decision self-efficacy, and reducing decisional conflict among potential living kidney donors.
- Trial name
- NCT07243717
- Testing
- Information-Assisted Intervention
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Kidney Transplant, Kidney Donor
Transforming Curiosity Into Donation
This is a multi-step study that will first create a preliminary living donor drop-out risk index (LD-DROP) by retrospectively identifying factors that contribute to the discontinuation of living donor evaluation.
- Conditions
- Kidney Transplant, Kidney Donor, Drop Out, High Risk
- Trial name
- NCT07793890
- Testing
- Living Kidney Donor Support
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Living-Kidney Donors
Dietary Interventions During Living Kidney Donations
Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney…
- Trial name
- DILKID (NCT05709600)
- Testing
- Fasting mimicking diet, Ketogenic diet, Dietary restriction of sulfur containing amino acids
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Healthy, Living Kidney Donation
Telemedicine to Support Living Kidney Donor Candidates
The goal of this feasibility clinical trial is to learn if telemedicine can be used to provide education and evaluation and counseling for people who are considering living kidney donation.
- Trial name
- NCT07206069
- Testing
- Standard Care (in control arm), Telemedicine Shared Decision-Making
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Postoperative Pain
Transversus Abdominis Plane Block Versus Wound Infiltration for Pulmonary Function Preservation Following Laparoscopic Living Donor Nephrectomy
This study compares two pain control techniques in patients undergoing laparoscopic kidney donation surgery: transversus abdominis plane (TAP) block versus wound infiltration with local anesthetic.
- Trial name
- TAPWIN (NCT06837909)
- Testing
- Transversus abdominis plane (TAP) block, Wound infiltration
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center