Clinical trials: Living-Donor Kidney Transplant
Kidney Transplantation
Abnormalities of Preoperative Ascending Urethrocystography and Outcomes of Living Donor Kidney Transplantation
To evaluate effects of abnormalities in preoperative ascending urethrocystography on the short-term outcomes of LDKT
- Trial name
- NCT06735066
- Testing
- Ascending urethrocystography
- Volunteers
- 80 people
- Sponsor
- Assiut University
End-Stage Renal Disease
Pediatric Kidney Transplant Without Calcineurin Inhibitors
The purpose of this study is to see the effect of using drugs other than calcineurin inhibitors to improve the rate of kidney transplant failure. Kidney transplantation can help children with end-stage kidney disease.
- Trial name
- NCT00023231
- Testing
- Daclizumab, Methylprednisolone/prednisone, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Living Donor Kidney Transplantation
Multidisciplinary Support to Access Living Donor Kidney Transplant (MuST AKT)
For people living with kidney failure, the two active treatment options are dialysis or kidney transplantation. Transplantation is optimal, and especially from a living donor - offering patients longer survival, a better quality…
- Trial name
- MuST AKT (NCT05459337)
- Testing
- MuST AKT
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Alberta
Renal Disease
Remote Ischemic Preconditioning Living Donor Renal Transplant Protocol
In this study, patients undergoing live donor kidney transplantation will be allocated to the control group or remote ischemic preconditioning group (RIPC).
- Trial name
- NCT03084666
- Testing
- Zimmer ATS tourniquet system
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Disease
Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants
Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired…
- Trial name
- NCT00018785
- Testing
- donor bone marrow infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Kidney Transplant, Kidney Transplant Donor
Outcomes of a Pre-operative Exercise Programme for Live Donor and Recipient Kidney Transplant Patients
The goal of this clinical trial is to learn if a pre-operative outpatient exercise programme, monitored by a smart wearable device is acceptable to live kidney donor and recipient transplant patients.
- Conditions
- Kidney Transplant, Kidney Transplant Donor, Kidney Transplant Recipient
- Trial name
- OPERATe (NCT06858098)
- Testing
- Exercise programme, Wearable smart device
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Manchester
Kidney Transplant Candidates
Increasing Communication About Live Donor Kidney Transplant
This study will test the efficacy of a communication intervention intended to increase and improve kidney transplant candidates' communication about live donor kidney transplantation.
- Trial name
- NCT01855438
- Testing
- Living Donor Transplant Education
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Virginia Commonwealth University
Renal Transplant
Belatacept to Prevent Organ Rejection in Kidney Transplant Patients
Belatacept is an experimental medication shown in clinical trials to have immune system suppression properties in people who have had renal (e.g., kidney) transplants.
- Trial name
- BESTT (NCT00346151)
- Testing
- Belatacept, Sirolimus, Anti-thymocyte globulin
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Kidney Transplantation, HBV
Stratified vs Routine Prophylaxis in Living Kidney Transplantation From HBsAg+ Donors to HBsAg- Recipients
This is a multicenter, prospective, observational study to compare the efficacy and safety of stratified prophylaxis based on donors' and recipients' risk factors vs routine prophylaxis bases on clinical experience in living…
- Trial name
- NCT04562051
- Testing
- prophylaxis regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Kidney Transplant Failure and Rejection, Gender
Sex Impact on Long-term Outcomes of LDKT
The impact of donor and recipient gender combination on kidney transplant outcomes has been reported in several studies. The results vary greatly due to different factors, such as minor histocompatibility antigens, nephron…
- Trial name
- NCT06016283
- Where
- Netherlands
- Volunteers
- 1,276 people
- Sponsor
- Erasmus Medical Center
Living Donor Kidney Transplants Patients
Comparison of Tacrolimus and Myfortic Versus Tacrolimus and Sirolimus
The investigators center has also analyzed data over the last 7 years from deceased donor (DD) and living donor (LD) kidney transplant recipients who were randomized into 3 immunosuppressive arms between 2000 and 2001.
- Trial name
- NCT01038505
- Testing
- Tacrolimus, Myfortic and Sirolimus
- Sponsor
- University of Miami
Postoperative Pain, Kidney Transplant; Complications
Thread Embedding Acupuncture vs Sham on Acute Pain and Quality of Life After Laparoscopic Nephrectomy of Living Donor
This randomized, double-blind controlled study aims to evaluate the effectiveness of thread implantation acupuncture at EX-B2 L1 in reducing postoperative pain and improving quality of life in patients undergoing laparoscopic…
- Trial name
- NCT07243301
- Testing
- Thread implantation acupuncture
- Where
- Indonesia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Liver Transplant; Complications, AKI - Acute Kidney Injury
The Efficacy of Intravenous Amino Acids in Reducing the Occurrence of AKI After Live Donor Liver Transplant
This prospective, open-label, randomized controlled trial aims to evaluate the efficacy of intravenous amino acid infusion in reducing AKI after LDLT.
- Trial name
- NCT07132697
- Testing
- L-Amino acid mixture, Standard of care
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
End Stage Renal Disease, Living Donor Kidney Transplantation
Social Networks and Renal Education: Promoting Transplantation
There are significant and persistent disparities in access to kidney transplantation and as a result most patients with end stage renal disease receive hemodialysis (HD).
- Conditions
- End Stage Renal Disease, Living Donor Kidney Transplantation, Renal Dialysis
- Trial name
- SNARE (NCT03536858)
- Testing
- COACH (Communicating about Choices in Transplantation)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Temple University
End-stage Renal Failure, Kidney Graft Rejection
Reference Group Trial for The ONE Study
To investigate the progression of the immunological response in living-donor kidney transplant recipients treated with a standard immunosuppressive regimen.
- Trial name
- NCT01656135
- Testing
- Blood drawing for immune monitoring and questionnaires
- Where
- 8 sites in United States, France and 3 more
- Volunteers
- 70 people
- Sponsor
- University of Regensburg
Kidney Transplant Rejection, End Stage Renal Disease
Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients
The purpose of this study is to evaluate the safety and tolerability of TX200-TR101 and its effects on the donated kidney in living donor kidney transplant recipients.
- Trial name
- STEADFAST (NCT04817774)
- Testing
- TX200-TR101
- Where
- 5 sites in Belgium, Netherlands and 1 more
- Volunteers
- 26 people
- Sponsor
- Sangamo Therapeutics
Kidney Transplantation, Multiparametric Magnetic Resonance Imaging
Multiparametric MRI in a Prospective Cohort of Living Kidney Donors, Recipients, and Healthy Controls: Correlations With Markers of Renal Function, Fibrosis and Ageing
Development of renal fibrosis is the irreversible culmination of various renal diseases and independently predicts adverse outcomes. Currently renal fibrosis can only be diagnosed by performing a renal biopsy.
- Conditions
- Kidney Transplantation, Multiparametric Magnetic Resonance Imaging, Living Donors, Renal Fibrosis
- Trial name
- MpRenal (NCT06210555)
- Testing
- Renal transplantation, Living kidney donation
- Where
- 2 sites in Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Patrick Schjelderup
Transplant, Kidney Diseases
Donor Outcomes Following Hand-Assisted and Robotic Living Donor Nephrectomy: a Retrospective Review
1.1. Background: Renal transplantation is the treatment of choice for eligible patients with end-stage renal disease. It provides better outcomes in terms of life expectancy and quality of life than dialysis (Liu, Narins, Maley…
- Trial name
- NCT04182607
- Testing
- kidney transplant
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Methodist Health System
Transplant; Failure, Kidney
XM-One Study for Living Donor Program
Donor-Specific Antibody (DSA) (HLA) levels and non-HLA antibody levels in recipients prior to living kidney transplantation and randomize these individuals into a desensitization protocol in order to evaluate shifts that can…
- Trial name
- NCT01679184
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Cytomegalovirus (CMV) Infection, Kidney Transplantation
A Study of CMV Vaccine (HB-101) in Kidney Transplant Patients
HB-101 is a bivalent recombinant vaccine against human CMV infection. This is a randomized, placebo-controlled, phase 2 study to assess the safety, reactogenicity, immunogenicity, and efficacy of HB-101 in CMV-Seronegative…
- Trial name
- NCT03629080
- Testing
- HB-101 vaccine
- Where
- 25 sites in United States, Denmark and 4 more
- Volunteers
- 83 people
- Sponsor
- Hookipa Biotech GmbH