Clinical trials: Living-Kidney Donors
Chronic Kidney Diseases
System Interventions to Achieve Early and Equitable Transplants Study - Long-Term
STEPS-LT is an extension of the System Interventions to Achieve Early and Equitable Transplants (STEPS) study. STEPS-LT will follow participants that previously completed the STEPS study to evaluate sustained behavioral…
- Trial name
- STEPS-LT (NCT07515794)
- Where
- United States
- Volunteers
- 793 people
- Sponsor
- Wake Forest University Health Sciences
Kidney Transplantation, HBV
Stratified vs Routine Prophylaxis in Living Kidney Transplantation From HBsAg+ Donors to HBsAg- Recipients
This is a multicenter, prospective, observational study to compare the efficacy and safety of stratified prophylaxis based on donors' and recipients' risk factors vs routine prophylaxis bases on clinical experience in living…
- Trial name
- NCT04562051
- Testing
- prophylaxis regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Renal Transplantation
Effect of Probiotics on Immunosuppressive-drug-associated Diarrhea Among Renal Transplant Recipients
The goal of this pilot project is to 1) examine whether oral administration of probiotics are helpful in reducing immunosuppressive drugs-associated diarrhea and adhering to the required dose of immunosuppressive drugs and 2)…
- Trial name
- NCT06150287
- Testing
- Florajen Digestion
- Volunteers
- 70 people
- Sponsor
- State University of New York - Upstate Medical University
Kidney Damage
To Evaluate the Renal Tubular Function Pre and Post Nephrectomy in Living Donors
The overall goals of this study are to demonstrate the change in renal tubular function in living donors pre and post nephrectomy at 6 months.
- Trial name
- NCT03676361
- Testing
- Desmopressin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Living Kidney Donation
The Living Kidney Donor Safety Study
The main goal of this study is to understand the long-term effects of kidney donation on blood pressure, kidney function, and patient-reported health-related quality of life.
- Trial name
- LKD (NCT00936078)
- Where
- 13 sites in Australia, Canada
- Volunteers
- 1,438 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Disease
Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants
Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired…
- Trial name
- NCT00018785
- Testing
- donor bone marrow infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Transplant, Kidney Diseases
Donor Outcomes Following Hand-Assisted and Robotic Living Donor Nephrectomy: a Retrospective Review
1.1. Background: Renal transplantation is the treatment of choice for eligible patients with end-stage renal disease. It provides better outcomes in terms of life expectancy and quality of life than dialysis (Liu, Narins, Maley…
- Trial name
- NCT04182607
- Testing
- kidney transplant
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Methodist Health System
Kidney Transplant Candidates
Imlifidase in Living Donor Renal Transplantation Highly Sensitized Recipients
This is a Phase II, pilot, prospective, unicentric trial, to evaluate Imlifidase could improve the transplantability of the highly sensitized patients with good outcomes respect to survival and functionality of the graft.
- Trial name
- LIVEDES (NCT06461546)
- Testing
- Imlifidase
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Living Renal Donor
Renal Donor Comparison of Outcomes: Hand Assist Versus Laparoscopic Nephrectomy
This study is designed to look at outcomes of patients who have undergone hand assisted laparoscopic donor nephrectomy versus totally laparoscopic donor nephrectomy.
- Trial name
- NCT00460889
- Testing
- donor nephrectomy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Kidney Transplantation
A Safety and Efficacy Study of FCR001 Cell Therapy in Previously Transplanted Living Donor Kidney Recipients
An open-label study to assess the safety, tolerability, and efficacy of FCR001 cell therapy in adult recipients 3-12 months after kidney transplantation from a living donor.
- Trial name
- FREEDOM-2 (NCT01649388)
- Testing
- FCR001
- Where
- 3 sites in United States
- Sponsor
- Talaris Therapeutics Inc.
End-stage Renal Disease, Chronic Kidney Diseases
Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication
The study is a- 2-arm randomized controlled trial among patients presenting for kidney transplant evaluation at a single transplant center to compare the effects of a patient-based self-learning and outreach intervention about…
- Trial name
- KidneyTIME (NCT05154773)
- Testing
- Kidney donation and transplant information made easy
- Where
- United States
- Volunteers
- 422 people
- Sponsor
- State University of New York at Buffalo
Kidney Transplant Failure and Rejection
A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression
This is an open label, single-center, randomized phase IV pilot study of steroid and calcineurin inhibitor avoidance in renal transplant recipients.
- Trial name
- Cell220 (NCT00166712)
- Testing
- Tacrolimus (TAC), Sirolimus, Alemtuzumab
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Chronic Pain, Living Kidney Donor
The Effect of Quadratus Lumborum (QL) Block on the Incidence of Chronic Neuropathic Pain After Retroperitoneal Laparoscopic Donor Nephrectomy: A Study on Neuroinflammation and Neurophysiology
To analyze the relationship of anterior subcostal quadratus lumborum (QL) block compared with control block on the incidence of chronic neuropathic pain at three months post-laparoscopic retroperitoneal living kidney donor.
- Conditions
- Chronic Pain, Living Kidney Donor, Quadratus Lumborum Block, Laparoscopic Donor Nephrectomy
- Trial name
- NCT07037992
- Testing
- injection of local anesthesia solution, Injection of normal saline
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Acute Kidney Injury, Hyperglycemia
Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation
This retrospective cohort study of patients classified by the blood glucose level after reperfusion in liver transplantation repicient.
- Conditions
- Acute Kidney Injury, Hyperglycemia, Hypoglycemia, End Stage Liver Disease
- Trial name
- NCT06320730
- Testing
- Observational study, records of blood glucose level after reperfusion
- Where
- South Korea
- Volunteers
- 3,790 people
- Sponsor
- Asan Medical Center
Nephrectomy
Recovery of Short-term Renal Function in Post-transplant Patients Living Donor
Objectives: To describe and analyze the perioperative and functional evolution of short-term renal graft in patients with kidney transplantation from a live donor, comparing three surgical techniques for obtaining kidney graft…
- Trial name
- NCT03717259
- Testing
- Open nephrectomy, Hand-assisted laparoscopic nephrectomy, Laparoscopic nephrectomy
- Volunteers
- 508 people
- Sponsor
- Instituto Mexicano del Seguro Social
HIV Infections
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
- Trial name
- NCT03408106
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University