Clinical trials: Living-Kidney Donors
Acute Kidney Injury, Hyperglycemia
Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation
This retrospective cohort study of patients classified by the blood glucose level after reperfusion in liver transplantation repicient.
- Conditions
- Acute Kidney Injury, Hyperglycemia, Hypoglycemia, End Stage Liver Disease
- Trial name
- NCT06320730
- Testing
- Observational study, records of blood glucose level after reperfusion
- Where
- South Korea
- Volunteers
- 3,790 people
- Sponsor
- Asan Medical Center
Cytomegalovirus Infections
Valganciclovir Prophylaxis Versus Preemptive Therapy for Cytomegalovirus in Living Donor Kidney Transplant Recipients
Cytomegalovirus (CMV) infection remains one of the most frequent infectious complications after kidney transplantation. In intermediate-risk recipients (seropositive, R+ recipient) of living donor kidney transplants, optimal…
- Trial name
- (PREVAIL-KT) (NCT07430683)
- Testing
- Valganciclovir Prophylaxis, Preemptive Therapy (CMV PCR Monitoring)
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- University of Guadalajara
Kidney Transplantation, HBV
Stratified vs Routine Prophylaxis in Living Kidney Transplantation From HBsAg+ Donors to HBsAg- Recipients
This is a multicenter, prospective, observational study to compare the efficacy and safety of stratified prophylaxis based on donors' and recipients' risk factors vs routine prophylaxis bases on clinical experience in living…
- Trial name
- NCT04562051
- Testing
- prophylaxis regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Kidney Transplant
Eculizumab to Prevent Antibody-mediated Rejection in ABO Blood Group Incompatible Living Donor Kidney Transplantation
The purpose of this study is to try to determine if the drug eculizumab can help prevent antibody-mediated rejection in patients undergoing a kidney transplant from a living donor with a different blood type than their own.
- Trial name
- ABOi (NCT01095887)
- Testing
- Eculizumab
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Transplant Recipient (Kidney)
Clinical and Immunological Outcomes of Living and Deceased Donor Transplantation
This is a retrospective, prospective, single-centre, non-pharmacological observational study. The primary objective is to investigate the long-term prognosis of the kidney transplant function of different types of donors.
- Trial name
- TxBo2022 (NCT06759831)
- Where
- Italy
- Volunteers
- 1,293 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
ESRD
Combined Blood Stem Cell and Kidney Transplant of One Haplotype Match Living Donor Pairs.
The Stanford Medical Center Program in Multi-Organ Transplantation and the Division of Bone marrow Transplantation are enrolling patients into a research study to determine if donor stem cells given after a living related one…
- Trial name
- NCT01165762
- Testing
- Immune Tolerance
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Everett Meyer
Chronic Kidney Diseases, Apolipoprotein L1
APOL1 Genetic Testing Program for Living Donors
Living donor (LD) kidney transplantation is the optimal treatment for patients with end-stage kidney disease (ESKD). However, LDs take on a higher risk of future ESKD themselves.
- Conditions
- Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
- Trial name
- NCT04910867
- Testing
- Components of Genetic Counseling, APOL1 genetic testing, EHR integration
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Northwestern University
Living Kidney Donors
Pilot Prospective Study: Long-term Health of Living Kidney Donors
Kidney transplantation, a 'miracle' of modern medicine, is the preferred treatment option for End Stage Renal Disease compared to dialysis, patients who receive kidneys have a 70% reduction in risk of death, a dramatically…
- Trial name
- NCT00319579
- Where
- 15 sites in United States, Australia and 1 more
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Amit Garg
Renal Transplantation
Outcome of Living Donor Renal Transplantation in Assiut Urology and Nephrology University Hospital ,Initial Experience
evaluation of outcome of living donor renal transplantation in assiut urology and nephrology university Hospital regarding the survival of patients and grafts , complications and quality of life after transplantation.
- Trial name
- NCT03338140
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pain
Pregabalin on Interleukin-6 Levels in Living Donor Kidney
Pregabalin, a ligand for alfa2delta subunits of voltage-gated calcium channels, has been shown to be an effective adjuvant therapy for acute postoperative pain, by inhibiting central sensitization.
- Trial name
- NCT01529190
- Testing
- Pregabalin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Hypertension, Living Kidney Donor
Dietary Sodium Intake and Blood Pressure in Living Kidney Donors
This is a pilot study to determine the feasibility of the study design and examine the main outcome whether low dietary sodium intake is superior to high dietary sodium intake in controlling blood pressure to be within the…
- Conditions
- Hypertension, Living Kidney Donor, Dietary Sodium Intake
- Trial name
- SPLID (NCT05041829)
- Testing
- Dietary sodium
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
HIV Infections
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
- Trial name
- NCT03408106
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Kidney Diseases, Kidney Failure, Chronic
Effect of Remote Ischaemic Preconditioning on Renal Function in Patients Undergoing Living Donor Kidney Transplantation
The purpose of this study was to investigate whether lower limb ischaemic preconditioning can improve renal function in patients undergoing living donor kidney transplantation
- Conditions
- Kidney Diseases, Kidney Failure, Chronic, Kidney Failure, Renal Insufficiency
- Trial name
- NCT01289548
- Testing
- remote ischaemic preconditioning
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Kidney Disease, Kidney Transplant
Strategies to Transform Kidney Care and Improve Pursuit of Transplant
Approximately 15% of the U.S. population has chronic kidney disease, and ~700,000 patients are in full kidney failure also called end-stage kidney disease (ESKD).
- Conditions
- Kidney Disease, Kidney Transplant, Deceased Donor Kidney Transplant, Living Donor Kidney Transplantation
- Trial name
- NCT07794631
- Testing
- Digital Health Integration, Training for Early Transplant Access and Support, Kidney Health Mobile Health (mHealth) Application
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
End-Stage Renal Disease, Living Donors
Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation
The purpose of this study is to observe in a randomized prospective study the effectiveness and toxicity of Thymoglobulin vs. Campath-1H used for induction therapy in recipients of living donor (LD) kidneys, compared with the…
- Trial name
- NCT01046955
- Testing
- Anti-Thymocyte Globulin vs Campath-1H vs Daclizumab
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Renal Transplant Recipients
Research Study of ATG and Rituximab in Renal Transplantation
The purpose of this study is see if a combination of two drugs, (ATG and rituximab), given at the time of the transplant surgery, will help reduce or eliminate the need for long term immunosuppressive medication.
- Trial name
- RESTARRT (NCT01318915)
- Testing
- ATG, Rituximab, Tacrolimus
- Where
- 6 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
End-stage Renal Failure, Kidney Graft Rejection
Reference Group Trial for The ONE Study
To investigate the progression of the immunological response in living-donor kidney transplant recipients treated with a standard immunosuppressive regimen.
- Trial name
- NCT01656135
- Testing
- Blood drawing for immune monitoring and questionnaires
- Where
- 8 sites in United States, France and 3 more
- Volunteers
- 70 people
- Sponsor
- University of Regensburg
Kidney Transplantation, Nephrectomy,Kidney Donation
A Qualitative Study on Gratitude and Recognition Toward Living Kidney Donors
Kidney transplantation is widely recognized as the best treatment for patients with end-stage renal disease. However, its development is limited by the persistent shortage of available organs.
- Trial name
- GRACE (NCT07254546)
- Testing
- Semi-structured qualitative interview
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Transplant, Kidney Diseases
Donor Outcomes Following Hand-Assisted and Robotic Living Donor Nephrectomy: a Retrospective Review
1.1. Background: Renal transplantation is the treatment of choice for eligible patients with end-stage renal disease. It provides better outcomes in terms of life expectancy and quality of life than dialysis (Liu, Narins, Maley…
- Trial name
- NCT04182607
- Testing
- kidney transplant
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Methodist Health System
End Stage Renal Disease
Tolerance Induction in Living Donor Kidney Transplantation With Hematopoietic Stem Cell Transplantation
Kidney transplantation (KT) requires a life-long immune suppression (IS). It has been well-known that long-term IS inevitably causes various complication e.g.
- Trial name
- NCT02199301
- Testing
- Transplantation Conditioning for BMT
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Samsung Medical Center