Clinical trials: Lobectomy
Post-operative Pain
Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing VATS Lobectomy
This study will compare ESP block plus patient-controlled analgesia (PCA) to intercostal nerve block plus PCA as post-operative pain control for patients having video-assisted thorascopic surgeries.
- Trial name
- NCT03176667
- Testing
- Ultrasound guided erector spinae plane block, Intercostal block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Pulmonary Artery Stenosis
Evaluation of Visceral Pleural Lumbar Lymphatic Drainage
Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS).
- Trial name
- SEGPUL (NCT03628326)
- Testing
- Pulmonary arterial tree
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lobotomy Syndrome
Acapella vs Flutter Devices for Improving Breathing and Lung Function After Lobectomy
Lobectomy patients frequently experience postoperative respiratory complications such as secretion retention, dyspnea, impaired gas exchange, and reduced lung function, which can delay recovery.
- Trial name
- NCT07737093
- Testing
- Acapella Device Therapy (Experimental Arm 1):, Flutter Device Therapy (Experimental Arm 2):
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Carcinoma, Non-Small-Cell Lung
The Effect of a Combined Drainage Strategy in Uniportal Upper Lung Lobectomy
Traditional drainage for uniportal video assisted thoracoscopic surgery (VATS) is a routine method, usually with one or two chest tubes at intercostal incisions, but postoperative pain due to the chest tube and unsatisfied…
- Trial name
- NCT04461652
- Testing
- prophylactic air-extraction catheter drainage
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tongji University
Lung Cancer
Effects of Open Thoracic Paravertebral Block on Postoperative Analgesia
The study was aimed to assess the effects of open thoracic paravertebral block on postoperative analgesia in patients undergoing open pulmonary lobectomy under general anesthesia.
- Trial name
- NCT03449563
- Testing
- Open TPVB, Ultrasound-guided TPVB
- Volunteers
- 90 people
- Sponsor
- Kunming Medical University
Papillary Thyroid Cancer
Image-guided Thermal Ablation vs. Lobectomy for Solitary Papillary Thyroid Microcarcinoma
To evaluate the clinical outcomes of image-guided thermal ablation versus thyroid lobectomy for the treatment of papillary thyroid microcarcinoma
- Trial name
- NCT06325787
- Testing
- thyroid lobectomy, image-guided thermal ablation
- Volunteers
- 1,021 people
- Sponsor
- Chinese PLA General Hospital
Lung Cancer Stage I
Outside the Cage (OTC) Robotic Lobectomy
This study consists in a prospective pilot study evaluating the feasibility and safety of OTC RATS lobectomies in patients treated for lung cancer.
- Trial name
- OTC-RATS (NCT05832112)
- Testing
- VATS/RATS lobectomy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Adenocarcinoma
Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
This study aims to evaluate the superiority in recurrence-free survival of lobectomy compared with segmentectomy in patients with lung adenocarcinoma ≤ 2 cm with micropapillary and solid subtype positive by intraoperative frozen…
- Trial name
- NCT05838053
- Testing
- Lobectomy with systemic lymph node dissection, Segmentectomy with systemic lymph node dissection
- Where
- China
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Thyroid Cancer, Papillary Thyroid Microcarcinoma
Multicenter Comparison of Thermal Ablation Versus Thyroid Lobectomy for Subcapsular Papillary Thyroid Microcarcinoma
To compare the clinical outcomes of Thermal ablation with those of thyroid lobectomy in patients with subcapsular papillary thyroid microcarcinoma.
- Trial name
- NCT06583057
- Testing
- Thermal ablation, Thyroid lobectomy
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese PLA General Hospital
Pulmonary Air Leak, Lobectomy
Digital Versus Analog Pleural Drainage Following Pulmonary Resection
This study will evaluate the impact of continuous, digital pulmonary air leak monitoring on the duration of pleural drainage after lung resection in patients with and without a pulmonary air leak on postoperative day 1.
- Conditions
- Pulmonary Air Leak, Lobectomy, Wedge Resection, Segmentectomy
- Trial name
- DiVA Phase II (NCT01775657)
- Testing
- Thopaz (Digital drainage), Pleur Evac (Analogue drainage)
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- Ottawa Hospital Research Institute
Thyroid Gland Medullary Carcinoma
STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection
This clinical trial studies how well thyroid lobectomy with ipsilateral central neck dissection works to treat medullary thyroid cancer (MTC) in patients without a germline RET mutation (sporadic).
- Trial name
- NCT07612293
- Testing
- Biospecimen Collection, FDG-Positron Emission Tomography and Computed Tomography Scan, Ga-68 PET/CT Scan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Pain
Post-Operative Pain After Uniportal Vats Lobectomy: Does A Smaller Incision Result In Better Recovery?
Post-Operative Pain After Uniportal Vats Lobectomy: Does A Smaller Incision Result In Better Recovery? Postoperative pain control remains one of the most common problems after major lung resection.
- Trial name
- NCT03218098
- Testing
- Lobectomy via UVATS
- Volunteers
- 44 people
- Sponsor
- University of Roma La Sapienza
Acute Lung Injury
Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage
Background: In patients undergoing lung lobectomy, lung collapse and re-expansion after resection is associated to severe oxidative lung injury.
- Trial name
- NCT02734654
- Testing
- remote ischemic preconditioning (RIPC)
- Volunteers
- 53 people
- Sponsor
- Instituto de Salud Carlos III
Lung Cancer Patients
Inter Costal Catheters for Video-Assisted Thoroscopic (VATS) Lobectomy
A pilot study to observe satisfaction of analgesia with intercostal catheters after VATS lobectomy.
- Trial name
- NCT01213654
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lung Cancer
Comparison of Efficacy of Paravertebral and Epidural Analgesia After Videothoracoscopic Lung Lobectomy
Thoracic surgery correlates with significant pain in postoperative period. In order to alleviate the pain various combinations of pharmaceuticals and administration methods are employed.
- Trial name
- NCT02040662
- Testing
- Continuous Thoracic Epidural Block, Continuous Thoracic Paravertebral Block, Patient-Controlled Analgesia with Morphine
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Pulmonary Hospital Zakopane
Early Stage Non-small-cell Lung Cancer (Stage 1-2)
Assessment of Ergonomics in 3D vs 2D Thoracoscopic Lobectomy
Video-assisted thoracic surgery (VATS) pulmonary lobectomy is currently widely employed as the first treatment option for surgical management of early stage (stage I-II) non-small-cell-lung-cancer (NSCLC).
- Trial name
- NCT03925103
- Testing
- 3D VATS lobectomy, 2D VATS lobectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Rome Tor Vergata
Lung Cancer, Surgery
Comparison of Sublobar Resection and Lobectomy to Treat Lung Cancer
A multi-center prospective randomized trial in Taiwan to investigate whether sublobar resection, as compared to lobectomy, can offer equivalent clinical results to treat early non-small cell lung cancer.
- Trial name
- NCT03185754
- Testing
- Sublobar resection, lobectomy
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Lung Neoplasms
Effects of Early Mobilization and Feeding After Lobectomy
This randomized controlled study evaluates the effects of early mobilization and early oral feeding, two components of the Enhanced Recovery After Surgery (ERAS) protocol, on postoperative outcomes in adult patients with lung…
- Trial name
- NCT07749950
- Testing
- Early Mobilization, Early Oral Feeding, Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ege University
Lung Cancer (Diagnosis)
Combination Versus Alone Liposomal Bupivacaine Blocks in Minimally Invasive Thoracic Surgery-1
The goal of this clinical trial is to assess how the location of local anesthetic medication affects pain control capabilities in adult patients undergoing thoracic(chest)-only minimally invasive surgery.
- Trial name
- CALMS-1 (NCT07254650)
- Testing
- Arm 1 "LipoB-I": Liposomal Bupivacaine via Multi-Level Intercostal Nerve Block, Arm 2 "LipoB-S": Liposomal Bupivacaine via Serratus Anterior Plane Block, Arm 3 "LipoB-C": Liposomal Bupivacaine Administered via Combination Block
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Carcinoma, Non-Small-Cell Lung, Pain, Postoperative
Why in Hospital After VATS Lobectomy
The study aims to identify specific or potential reasons that prolong the length of hospital stay after video-assisted thoracoscopic surgery lobectomy.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Pain, Postoperative, Postoperative Nausea and Vomiting, Infection
- Trial name
- NCT04294108
- Testing
- Prolong in-hospital stay
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet