Clinical trials: Locomotion Disorder, Neurologic
Parkinson's Disease
Spinal Cord Stimulation for the Treatment of Motor and Nonmotor Symptoms of Parkinson's Disease
Although DBS improves patient's quality of life advanced Parkinson's patients (PD) by addressing the cardinal symptoms and reducing levodopa motor complications, symptoms still worsen over time.
- Trial name
- SCSPD (NCT02388204)
- Testing
- Implantable spinal cord stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Parkinson Disease, Parkinson Disease 10
Effects of Different Physical Therapies and Dance in People With Parkinson's Disease
The aim of study is to analyze the effects of different physical therapies (Aquatic Jogging, Neurofunctional Physiotherapy, Pilates Training and Nordic Walking) and Dance and compare with unsupervised home exercises in the…
- Trial name
- NCT03860649
- Testing
- Nordic Walking, Jogging, Dance
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Rio Grande do Sul
Stroke
Very Intensive Variable Repetitive AmbulatioN Training
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients…
- Trial name
- VIVRANT (NCT02507466)
- Testing
- exercise
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Cancer, Child, Only
Horse Assisted Rehabilitation Postoncologic Treatment in Children and Adolescents: Physical and Psychological Effects
Clinical trial on the physical and psychological effects of Horse Assisted Rehabilitation after the treatment of cancer in children 4 to 18 years of age.
- Conditions
- Cancer, Child, Only, Child Behavior, Neurologic Gait Disorder
- Trial name
- NCT04070131
- Testing
- Horse-Assisted Rehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Escoles Universitaries Gimbernat
Neurologic Gait Disorder
Myosuit-based Gait Training
This study will investigate the safety and feasibility of over-ground training sessions with the Myosuit for the neurological inpatients of rehabilitation clinic Zihlschlacht with a gait disorder and their therapists.
- Trial name
- NCT05485597
- Testing
- Myosuit-based gait training
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Rehaklinik Zihlschlacht AG
Rehabilitation
Motor Imagery Practice on Amputees (MIPA)
Motor imagery practice (MIP), which is the repeated internal representation of a movement without engaging its physical execution and which shares a neurofunctional equivalence with physical practice, has been show to contribute…
- Trial name
- MIPA (NCT03125538)
- Testing
- Motor Imagery, Control Task
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Laboratoire Interuniversitaire de Biologie de la Motricité
Spinal Cord Injuries
Improving Gait in Patients With Spinal Cord Injuries
This study is part of a larger clinical trial that examines the potential of a 12-week treadmill-training program to improve walking in patients with spinal cord injuries (SCIs).
- Trial name
- NCT00060983
- Testing
- Body weight supported locomotor training, Functional electrical stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Gait, Frontal
Influence of Short-term Vojta Therapy on the Gait in Healthy Adult Subjects.
The patterns of reflex locomotion described by Vojta contain all the basic patterns necessary for gait, which can be observed as partial patterns during normal postural ontogenesis in the first year of life.
- Trial name
- V&G (NCT04689841)
- Testing
- Vojta Therapy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- NUMEN Foundation
Parkinson Disease, COPD
The ADAPT-study: Measuring Physical Performance Using Wearable Sensors in Parkinson's Disease and COPD (ADAPT)
The aim of this study is to investigate whether a smartwatch can measure the physical capacity of patients with Parkinson's Disease and COPD in the physiotherapy practice and at home.
- Trial name
- ADAPT (NCT05756075)
- Testing
- Aerobic exercise training
- Where
- 28 sites in Netherlands
- Volunteers
- 154 people
- Sponsor
- Radboud University Medical Center
Cerebral Vascular Accident
Analysis of the Psychometric Properties of Kinematic Parameters of Locomotion Measured by Inertial Units. Validation in Healthy Volunteers and Stroke Patients
Stroke is the leading cause of acquired disability in adults in France, and more than 500,000 French people are currently living with the after-effects.
- Trial name
- KAPP-IMU (NCT05104645)
- Testing
- Analysis of the walk, Analysis of the race, Unipodal and bipodal jumps on flat ground
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Spinal Cord Injuries
Epidural Stimulation and Resistance Training After SCI
Spinal cord injury (SCI) is a devastating health problem for tens of thousands of military personnel, Veterans and civilians annually. Many persons with SCI must use a wheelchair for their entire life.
- Trial name
- REST-SCI (NCT04782947)
- Testing
- Exoskeletal assisted walking, Epidural Stimulation, Resistance Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Department of Defense
Aging, Pain, Acute
Effects of Acute Pain on Motor Learning in Young vs Older Adults
To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its…
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Trial name
- NCT05471557
- Testing
- pain delivery
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Delaware
CP (Cerebral Palsy), Diplegia
Static and Dynamic Postural Stability in Cerebral Palsy Children
Cerebral palsy (CP) concerns 2 children out of 1000 in the general population (SCPE 2002). It is the main cause of postural and motor deficits in children.
- Conditions
- CP (Cerebral Palsy), Diplegia, Hemiplegia, Postural; Defect
- Trial name
- Dual-Task (NCT01799304)
- Testing
- no distractor control group, visual and sound attentional distractors, sound attentional distractor alone
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Grenoble
Spinal Cord Injuries, Non Invasive Spinal Stimulation
Development of a Novel Strategy to Analyze the Effect on Gait Using Transcutaneous Spinal Current Stimulation in Incomplete Spinal Cord Injured Patients
To determine whether the combination of non-invasive spinal cord stimulation together with gait rehabilitation reduces spasticity and facilitates recovery of lower limb motor strength and gait function in patients with incomplete…
- Conditions
- Spinal Cord Injuries, Non Invasive Spinal Stimulation, Gait Disorders, Neurologic, Motor Function; Retardation
- Trial name
- NCT07289191
- Testing
- transcutaneous spinal cord stimulation
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut Guttmann
Neurological Disorder
Effects of the Application of a Reflex Locomotion Program in the Neurological Hand
The recovery of the function of the hand is one of the most important aspects for patients who have suffered the consequences of neurological damage.
- Trial name
- NCT03890965
- Testing
- Reflex locomoction therapy
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- NUMEN Foundation
Stroke, Chronic Stroke
Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery
Despite current walking rehabilitation strategies, the majority of stroke survivors are unable to walking independently in the community and remain at increased risk of falls.
- Conditions
- Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
- Trial name
- BLT2 (NCT04553198)
- Testing
- Backward Locomotion Treadmill Training (BLTT)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Cincinnati
Spinal Cord Injury
The ATLET Study: Can Subjects With Incomplete Spinal Cord Injury Learn to Walk?
The ATLET study will assess the effect of manual or robotic body-weight supported locomotor training of patients with stable motor incomplete spinal cord injury (SCI) on gait and overall ADL function as well as on estimated…
- Trial name
- ATLET (NCT00854555)
- Testing
- Locomotor training with robot, Locomotor training with manual assistance
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- North Norway Rehabilitation Center
Parkinson's Disease
Effects of RAC With Locomotion Training on Cortical Excitability and Behavior in Patients With PD
In this study, 51 subjects include 17 freezers,17 non-freezers and 17 aged-matched healthy subjects will be recruited. We will compare the cortical excitability, gait performance, and stepping-in-place performance before and…
- Trial name
- NCT03656796
- Testing
- Treadmill training with auditory cues, Treadmill training without auditory cues
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injuries
Epidural Stimulation After Spinal Cord Injury
The purpose of the current study is to determine the effects of applying epidural stimulation (ES) on motor control recovery in Veterans with SCI.
- Trial name
- ESL-SCI (NCT04105296)
- Testing
- EKSO+ES
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- McGuire Research Institute
Spinal Cord Injuries, Paraplegia
Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
Many people with spinal cord injury (SCI) retain at least some movement below their injury, but their muscles often have a 'mind of their own'.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paraparesis
- Trial name
- NCT01740128
- Testing
- Robotic body weight supported treadmill training, Harness-supported multimodal balance training
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development