Clinical trials: Locomotion Disorder, Neurologic
Parkinson Disease, Gait Disorders
Effects of Biofeedback Footwear in Parkinson's Disease: Assessment of Functional Motor Abilities and Locomotion
The study aims to verify whether the use of a specific footwear providing increased plantar feedback (plantar feedback shoes) could improve gait parameters, postural control and functional performances in people with Parkinson's…
- Trial name
- NCT06453863
- Testing
- Greater plantar feedback shoes, Neutral gym shoes, Barefoot
- Volunteers
- 40 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Neurological Conditions, Brain Diseases
NEO-REEDUC - Mixed Reality for Motor Rehabilitation: a Prospective, Multicenter, Controlled, Randomized, Open Study.
This study aims to assess the effectiveness of a motor rehabilitation protocol that includes mixed reality activities, compared to conventional rehabilitation, on postural stability in children and adult patients with…
- Conditions
- Neurological Conditions, Brain Diseases, Cerebral Palsy, Parkinson Disease (PD)
- Trial name
- NCT07063810
- Testing
- Mixed Reality Rehabilitation
- Where
- 5 sites in France
- Volunteers
- 76 people
- Sponsor
- Slb Pharma
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
Neurologic Ambulation Disorder
Interactive Intensive Gait Training in Walking Limitations
Gait-MAP is a prospective, randomized, single-blind clinical trial designed to evaluate the effectiveness of an Intensive Interactive Gait Training (IIGT) program in adults with neurological conditions associated with pyramidal…
- Trial name
- Gait-MAP (NCT07899528)
- Testing
- Intensive Interactive Gait Training, Conventional Gait Rehabilitation
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- IRCCS San Raffaele Roma
Spinal Cord Injury
Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury
As a first-in-class (Central Pattern Generator or CPG activator) approach, this tritherapy candidate called SPINALON has been identified and is currently under development for its capacity to temporarily induce episodes of…
- Trial name
- NCT01484184
- Testing
- SPINALON (buspirone + levodopa + cardidopa)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nordic Life Science Pipeline Inc.
Multiple Sclerosis, Physical Therapy
Vojta Therapy in Multiple Sclerosis.
This Study evaluates the effectiveness of a Vojta locomotion reflex program as short-term automatic postural control in patients with Multiple sclerosis
- Trial name
- NCT03887507
- Testing
- Vojta Therapy, Standard Program
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- NUMEN Foundation
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Stroke, Locomotion Disorder, Neurologic
The Effect of Using Walking Aid On TUG Test
The Timed Up and Go Test is a measurement tool that allows the participant to use assistive devices and walking aids during the test that evaluates functional mobility.
- Trial name
- NCT05997472
- Testing
- evaluation af mobility and balance
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Bandırma Onyedi Eylül University
Stroke
Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke
The objective of this study is to determine the optimal training intensity and the minimum training duration needed to maximize immediate improvements in walking capacity in chronic stroke.
- Trial name
- NCT03760016
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Cincinnati
Stroke
Impaired Interlimb Coordination During Locomotion in Individuals With Chronic Stroke: Contributors and Effect on Walking Function
Individuals with chronic stroke have long-term walking problems that limit community engagement and quality of life, lead to secondary disabilities, and increase healthcare costs and burden.
- Trial name
- NCT07006818
- Testing
- Direct current stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Spinal Cord Injury
Xo-Motion R Exoskeleton in SCI-Adoption Study
After spinal cord injury (SCI), many people lose their ability to walk and do not have access to equipment and assistance that could help them regain functional abilities.
- Trial name
- NCT07380516
- Testing
- XoMotionR- assisted locomotor training
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Stroke
Fall Prevention and Locomotion Recovery in Post-stroke Patients: A Multimodal Training
The study proposes a novel rehabilitative program for the recovery of locomotor abilities in post-acute stroke patients. The hypothesis is that a rehabilitative program which involves a biofeedback cycling training combining…
- Trial name
- NCT02439515
- Testing
- Cycling, Balance, Standard physical therapy
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Fondazione Salvatore Maugeri
Gait Disorders
Impact of tDCS on Locomotion and Equilibrium in Hemiplegic Patients
The aim of this trial is to quantify the improvement of locomotion and equilibrium induced par tDCS in anode polarity position in post stroke hemiplegic patients.
- Trial name
- HEMILOCOSTICOR (NCT02134158)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Ischemic, Subacute Stroke
The Effect of BWSTT on Neuroendocrine Profile and Functional Recovery in Stroke Patients
The purpose of this study is to evaluate the impact of intensive Body Weight Support Treadmill Training (BWSTT) on the neuroendocrine system and functional recovery in patients during the subacute phase of ischemic stroke.
- Trial name
- NCT07443150
- Testing
- Body Weight Support Treadmill Training (BWSTT), Overground Training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Stroke
Robotic Exosuit Augmented Locomotion (REAL)
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL (NCT04818424)
- Testing
- Soft exosuit, Gait training without exosuits
- Where
- 3 sites in United States
- Sponsor
- Lou Awad, PT, DPT, PhD
Spinal Cord Injuries
Transcutaneous Spinal Stimulation and Exercise for Locomotion
Growing evidence indicates that electrical spinal cord stimulation improves motor functions both immediately and over the long term via modulating the excitability of spinal circuitry in patients with spinal cord injury.
- Trial name
- NCT03509558
- Testing
- Transcutaneous spinal stimulation, Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Parkinson Disease
Effects of a Dance and Walking Program for People With Parkinson's Disease
Parkinson's disease (PD), characterized as progressive and neurodegenerative, is one of the most frequent neurological diseases of the present time.
- Trial name
- DANCEPD (NCT03370315)
- Testing
- Dance Program, Walking Program
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Rio Grande do Sul
Central Nervous System Diseases
The Effect of Craniosacral Therapy as Additive Procedure.
This observational, retrospective study has shown, that the addition of craniosacral therapy to the Vojta method has improved the effects of the therapy in 6 months follow-up period.
- Trial name
- COREHNERV (NCT05722756)
- Testing
- craniosacral therapy
- Volunteers
- 51 people
- Sponsor
- Wroclaw Medical University
Parkinson's Disease
Stability and Balance in Locomotion Through Exercise
Persons with Morbus Parkinson commonly develop gait and balance disorders leading to dependence, loss of mobility and a high risk of falling.
- Trial name
- StaBLE (NCT01856244)
- Testing
- treadmill walking, Treadmill
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- University of Erlangen-Nürnberg