Clinical trials: Locomotor Activity
Cerebral Palsy
Short-Burst Interval Treadmill Training Cerebral Palsy
Ambulatory children with cerebral palsy (CP) walk predominately in low intensity stride rates with little variability, thus limiting their walking activity and ability to participate in daily life.
- Trial name
- NCT04026295
- Testing
- Short Burst Interval Treadmill Training (SBLTT), Traditional Locomotor Treadmill Training (TLTT)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kristie Bjornson
Gait Training, Locomotion
Gait Training and Brain Changes in Stroke Patients
This study, conducted in collaboration with the National Rehabilitation Hospital (NRH) in Washington, D.C., will look at changes in brain activation and brain responses that occur with gait (walking) training.
- Trial name
- NCT00334230
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Very Intensive Variable Repetitive AmbulatioN Training
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients…
- Trial name
- VIVRANT (NCT02507466)
- Testing
- exercise
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Hemiparesis, Stroke
Walking Therapy In Hemiparetic Stroke Patients Using Robotic-Assisted Treadmill Training
The overall goal of this study is to determine whether robotic-assisted gait training is better than standard physical therapy treatments for improving walking ability in hemiparetic stroke patients.
- Trial name
- NCT00075283
- Testing
- Lokomat (Robotic Orthosis) combined with slat belt treadmill
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- U.S. Department of Education
Amputation of Hip and Thigh, Level Unspecified
Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Moderately active amputees may have lost their limb due to diabetes, vascular conditions, trauma, tumour or congenital causes. These amputees currently cannot benefit from having a computerised knee because of the performance…
- Trial name
- NCT02382991
- Testing
- 3C60-NMPK, NMPK-3C60
- Where
- 15 sites in Austria, France and 1 more
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Otto Bock France SNC
Spinal Cord Injuries, Non Invasive Spinal Stimulation
Development of a Novel Strategy to Analyze the Effect on Gait Using Transcutaneous Spinal Current Stimulation in Incomplete Spinal Cord Injured Patients
To determine whether the combination of non-invasive spinal cord stimulation together with gait rehabilitation reduces spasticity and facilitates recovery of lower limb motor strength and gait function in patients with incomplete…
- Conditions
- Spinal Cord Injuries, Non Invasive Spinal Stimulation, Gait Disorders, Neurologic, Motor Function; Retardation
- Trial name
- NCT07289191
- Testing
- transcutaneous spinal cord stimulation
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut Guttmann
Parkinson Disease
Exploring the Effects of Spinal Cord Stimulation in Parkinson's Disease.
Parkinson Disease (PD) patients experience a variety of motor issues such as walking difficulties, loss of balance, and freezing while walking, which impacts their quality of life.
- Trial name
- SCS for FOG (NCT03526991)
- Testing
- Spinal Cord Stimulator (SCS)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Nora Vanegas
Spinal Cord Injury
Improving Walking After Spinal Cord Injury
Locomotor recovery is one of the most important goals of individuals with spinal cord injury (SCI). Ambulatory deficits severely impact daily functions resulting in lower quality of life for people living with paralysis due to…
- Trial name
- NCT07223710
- Testing
- Paired Associative Stimulation, Locomotor Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Hip Osteoarthritis, Indication for Total Hip Replacement
Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.
The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip…
- Trial name
- NCT02042586
- Testing
- Analysis of movement before total hip replacement, Analysis of movement after total hip replacement
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Amputation
An Uneven Terrain Surface to Improve Locomotor Robustness in People With Amputation
To attain high levels of mobility, people with lower limb amputation must build both the skill and the confidence to rely on their prosthesis in the environments that they will encounter in daily life.
- Trial name
- NCT05560061
- Testing
- Gait practice on an uneven terrain surface, Gait practice on a flat terrain surface
- Where
- United States
- Sponsor
- University of Nevada, Las Vegas
Spinal Cord Injury
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
Background: Body weight supported (BWS) locomotor training improves overground walking ability in individuals with motor-incomplete spinal cord injury (SCI).
- Trial name
- NCT01095380
- Testing
- Locomotor training
- Volunteers
- 74 people
- Sponsor
- University of Miami
Chronic Paraplegia
Training With Brain-machine Interfaces, Visuo-tactile Feedback and Assisted Locomotion for Patients With Chronic Complete Paraplegia
The purpose of this research is to compare the effectiveness of a training protocol integrating Brain-machine Interfaces, Visuo-tactile feedback and Assisted Locomotion (referred to as the Walk Again Neurorehabilitation protocol…
- Trial name
- NCT03992690
- Testing
- Brain-machine Interfaces, Visuo-tactile Feedback and Assisted Locomotion, or the WANR protocol, Training with traditional physiotherapy protocol
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Obesity and Overweight
Effect of Simulated Weight Loss on the Energy Cost of Locomotion in Overweight or Obese Adolescents
Current literature suggests that part of the energy response to weight loss is not due to changes in fat mass and lean mass, but rather to a homeostatic adaptation aimed at limiting or even preventing weight loss and preserving…
- Trial name
- DELOAD (NCT07155746)
- Testing
- Incremental walking exercise on an AlterG treadmill (anti-gravity)
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Emile Roux
Spinal Cord Injuries
Overground Walking Program With Robotic Exoskeleton in Long-term Manual Wheelchair Users With Spinal Cord Injury
Many individuals with a spinal cord injury (SCI) use a wheelchair as their primary mode of locomotion. The prolonged non-active sitting time associated to this mode of locomotion contributes to development or worsening of…
- Trial name
- NCT03989752
- Testing
- Wearable Robotic Exoskeleton for Ambulation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Locomotion Disorder, Neurologic
Non Motoric Reactions in Vojta Reflex Locomotion
Monitoring of non-motor manifestations of reflex locomotion according to Professor Vojta in laboratory conditions on healthy woman probands.
- Trial name
- VojtaRL (NCT06224491)
- Testing
- Reflex locomotion according to Vojta
- Where
- Czechia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Traumatic Amputation of Lower Extremity
Characterizing Ankle Function During Sloped Locomotion for Prosthesis Development
The proposed study aims to characterize biological ankle joint function during walking and running on slopes in order to further develop advanced powered ankle-foot prostheses.
- Trial name
- NCT01784003
- Testing
- Powered ankle-foot prosthesis
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Parkinson Disease
Effect of Auricular Stimulation on Locomotion in Patients With Parkinson's Disease
The effect of auricular stimulation on the locomotion capability in patients with Parkinson's Disease was investigated.
- Trial name
- NCT03907007
- Testing
- Percutaneous electrical nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Inventram
Patients With Chronic Stroke
Enhanced Motor Recovery Using Serotonergic Agents in Stroke
The information derived from this study will be critical to establishing appropriate rehabilitative interventions post-stroke. In particular, traditional use of pharmacological agents to alter motor function post-stroke is…
- Trial name
- NCT01751854
- Testing
- SSRI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Parkinson Disease
LONG TERM EFFECTS OF SPINAL CORD STIMULATION
Parkinson Disease (PD) patients experience a variety of motor issues such as walking difficulties, loss of balance, and freezing while walking, which impacts their quality of life.
- Trial name
- SCS for FOG OL (NCT06272955)
- Testing
- Spinal Cord Stimulator (SCS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nora Vanegas
Parkinson Disease, Parkinson Disease 10
Effects of Different Physical Therapies and Dance in People With Parkinson's Disease
The aim of study is to analyze the effects of different physical therapies (Aquatic Jogging, Neurofunctional Physiotherapy, Pilates Training and Nordic Walking) and Dance and compare with unsupervised home exercises in the…
- Trial name
- NCT03860649
- Testing
- Nordic Walking, Jogging, Dance
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Rio Grande do Sul