Clinical trials: Locomotor Activity
Type 2 Diabetes Mellitus
Impact of Muscle and Tendon Dysfunction in People With Type 2 Diabetes Mellitus
Diabetes is a chronic-degenerative metabolic disorder that has reached pandemic proportions mainly because of the increasing incidence and prevalence of type 2 diabetes mellitus (T2D).
- Trial name
- T2D_MTU (NCT05585502)
- Testing
- Training (minute oscillation stretching)
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Stroke
Rehabilitative Efficacy of a Visual Feedback Device for Locomotion of Post-stroke Patients
We tested the feasibility and efficacy of a novel body-weight support (BWS) gait training system with visual feedback, called Copernicus®.
- Trial name
- Copernicus (NCT04364490)
- Testing
- Copernicus noVF, Copernicis VF-Plus, Control group
- Where
- Italy
- Volunteers
- 162 people
- Sponsor
- S.Anna Rehabilitation Institute
Chronic Low Back Pain (non-specific, Uncomplicated), Walking
Exploring Locomotion Behavior of Chronic Non-Specific Low Back Pain (cNSLBP) Patients While Walking Through Apertures in Different Configurations: Influence of Environmental and Social Factors.
The biomechanical parameters studied in chronic non-specific low back pain (cNSLBP) patients in a locomotion task have so far focused on straight line walking.
- Trial name
- PERL3 (NCT06644053)
- Testing
- Quantified analysis of walking during a crossing task through different horizontal openings
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Spinal Cord Injuries
Epidural Stimulation and Resistance Training After SCI
Spinal cord injury (SCI) is a devastating health problem for tens of thousands of military personnel, Veterans and civilians annually. Many persons with SCI must use a wheelchair for their entire life.
- Trial name
- REST-SCI (NCT04782947)
- Testing
- Exoskeletal assisted walking, Epidural Stimulation, Resistance Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Department of Defense
Healthy Volunteers
Global Positioning Satellite and Accelerometry to Assess Human Locomotion (ACTI GPS)
The aim of the study is to validate the association of the GPS and accelerometer tools in order to assess the humain locomotion during exercises. The hypotheses are: 1.
- Trial name
- ActiGPS (NCT01805219)
- Testing
- GPS and accelerometer recording (s) during exercises
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Stroke, Chronic Stroke
Optimizing Training in Severe Post-Stroke Walking Impairment
Difficulty walking is common after a stroke. Although physical rehabilitation helps a little with the improvement of walking ability, recovery is usually incomplete.
- Conditions
- Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
- Trial name
- BLT2b (NCT04721860)
- Testing
- Backward Locomotion Treadmill Training (BLTT), Forward Locomotion Treadmill Training (FLTT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Cincinnati
Gait, Balance
Sensor Ankle Brace for Special Operations Rehabilitation - Phase 1
The primary purpose of this study overall is to validate a modified version of a commercially available ankle brace. Inertial measurement unit sensors incorporated into an existing ankle brace ("sXAB") by TayCo Brace, Inc.
- Conditions
- Gait, Balance, Biomechanical Data, Postural Control
- Trial name
- NCT07085416
- Testing
- Sensor-enabled Athletic X Ankle Brace (sXAB)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Indiana University
Spinal Cord Injuries
Activity Based Locomotor Exercise PrOgram-Wait-list controllEd Research
At Courage Kenny Rehabilitation Institute, rehabilitation for individuals with spinal cord injury (SCI) is being led by the NIH funded NeuroRecovery Network (NRN) Community Fitness and Wellness Program through the Activity-Based…
- Trial name
- ABLE-POWER (NCT03261388)
- Testing
- Activity-Based Locomotor Exercise Program (ABLE)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Allina Health System
Gait, Frontal
Influence of Short-term Vojta Therapy on the Gait in Healthy Adult Subjects.
The patterns of reflex locomotion described by Vojta contain all the basic patterns necessary for gait, which can be observed as partial patterns during normal postural ontogenesis in the first year of life.
- Trial name
- V&G (NCT04689841)
- Testing
- Vojta Therapy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- NUMEN Foundation
Stroke, Cerebral Vascular Disorders
Discrete Versus Rhythmic Gait Training
The objective of this study is to compare the effects of novel versus standard locomotor training using a robotic gait orthosis (LT-RGO) after stroke.
- Trial name
- NCT02650440
- Testing
- Novel Protocol, Standard Protocol
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Thais Amanda Rodrigues
Primary Hip Osteoarthritis
Adaptation of Locomotor Activity in Patients Suffering From Hip OA - Analysis of This Adaptation as a Prognostic Criterion for Future Disease Progression
To assess the prognostic value of a characteristic evaluation of gait in persons suffering from hip OA for subsequent indications for THR.
- Trial name
- NCT01907503
- Testing
- Evaluation of the balance of force platform
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Multiple Sclerosis
Biomechanical Characterization of the Locomotion in Multiple Sclerosis Patients
Multiple sclerosis (MS) is an inflammatory chronic disease of the central nervous system. Patients are suffering from balance and gait impairments at the early stage of the disease.
- Trial name
- WALKING-SEP (NCT03756142)
- Testing
- Motion Analysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Gait Disorders
Impact of tDCS on Locomotion and Equilibrium in Hemiplegic Patients
The aim of this trial is to quantify the improvement of locomotion and equilibrium induced par tDCS in anode polarity position in post stroke hemiplegic patients.
- Trial name
- HEMILOCOSTICOR (NCT02134158)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson Disease, Parkinson Disease 10
Effects of Different Physical Therapies and Dance in People With Parkinson's Disease
The aim of study is to analyze the effects of different physical therapies (Aquatic Jogging, Neurofunctional Physiotherapy, Pilates Training and Nordic Walking) and Dance and compare with unsupervised home exercises in the…
- Trial name
- NCT03860649
- Testing
- Nordic Walking, Jogging, Dance
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Rio Grande do Sul
Young Children With Motor Disabilities
Using Head-mounted, Eye-tracking to Compare Looking, Manual Exploration and Social Interaction During Active Locomotion
The three purposes of this study are: 1) to determine the feasibility of using a head-mounted eye-tracker and examine the effects of the optimal mobility training on increasing visual and manual exploration in toddlers with…
- Trial name
- NCT05441137
- Testing
- Ride-On Cars Training with Different Postures, Conventional Therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 72 people
- Sponsor
- Chang Gung Memorial Hospital
Patients With Chronic Stroke
Enhanced Motor Recovery Using Serotonergic Agents in Stroke
The information derived from this study will be critical to establishing appropriate rehabilitative interventions post-stroke. In particular, traditional use of pharmacological agents to alter motor function post-stroke is…
- Trial name
- NCT01751854
- Testing
- SSRI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke
The objective of this study is to determine the optimal training intensity and the minimum training duration needed to maximize immediate improvements in walking capacity in chronic stroke.
- Trial name
- NCT03760016
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Cincinnati
Pediatric Obesity, Lower Extremity Biomechanics
Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
Childhood obesity is one of the most critical and accelerating health challenges throughout the world. It is a major risk factor for developing varus/valgus misalignments of the knee joint.
- Trial name
- NCT02545764
- Testing
- Strength and neuromuscular exercise programme
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- St. Pölten University of Applied Sciences
Diabetes Mellitus, Leg Injuries
Prosthetic Components and Stability in Amputee Gait
The biomechanics of changing direction while walking has been largely neglected despite its relevancy to functional mobility. In addition, an increased risk of injury can be associated with turning due to a decrease in stability.
- Conditions
- Diabetes Mellitus, Leg Injuries, Traumatic Amputation
- Trial name
- NCT00167778
- Testing
- Transverse plane rotation adaptor pylon, Rigid pylon
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Amputation
An Uneven Terrain Surface to Improve Locomotor Robustness in People With Amputation
To attain high levels of mobility, people with lower limb amputation must build both the skill and the confidence to rely on their prosthesis in the environments that they will encounter in daily life.
- Trial name
- NCT05560061
- Testing
- Gait practice on an uneven terrain surface, Gait practice on a flat terrain surface
- Where
- United States
- Sponsor
- University of Nevada, Las Vegas