Clinical trials: Locomotor Activity
Healthy
Spinal Cord Plasticity
This study will examine the role of the spinal cord in improving leg movements after physical training in healthy people. The results of this study may be helpful in developing new rehabilitation therapies for people with…
- Trial name
- NCT00073606
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Retinitis Pigmentosa Syndrome
Evaluation of the Visual Field on the Ground
Retinopathy pigmentosa (which affects about 40,000 patients in France) leads to destruction of the peripheral retina. This condition, often familial, frequently affects young patients.
- Trial name
- ECVS (NCT03989622)
- Testing
- evaluation of the visual field on the ground
- Sponsor
- University Hospital, Limoges
Locomotor Activity
Gauging Outcomes of Locomotion Formats
Investigators intend to use Actiheart® Monitors with a cohort of 16-30 elite amateur golfers over 18 (male and female) from Tournament Golf to clarify golfer's energy expenditure across a round of 18 holes in each condition at a…
- Trial name
- GOLF (NCT06904833)
- Testing
- locomotion formats
- Where
- Portugal
- Volunteers
- 16 people
- Sponsor
- Liverpool John Moores University
Postural Balance
Evaluation of Foot Mechanical Information on Static Task and Locomotion
Sensory foot integration is evaluated by foam under feet both in research and clinical contexts. However, there is no norm defined regarding foam characteristics and this evaluation is mostly performed using a static task.
- Trial name
- NCT05170750
- Testing
- Foams, Foam / Orthopedic insole
- Where
- 2 sites in France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Lower Limb Amputation
Exploratory Functional Assessment After Lower Limb Amputation: Locomotion, Balance, Energy Performance and Strategies for Adapting to Orthopaedic Devices
The general aim of this exploratory study is therefore to investigate and quantify the functional capacities of patients with lower limb amputations (transtibial and transfemoral), with no change in their management, and to…
- Trial name
- AMILOCO (NCT07094074)
- Testing
- Walk tests, Functional testing, Balance analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Stroke
Robotic Exosuit Augmented Locomotion (REAL) in the Clinic and Community
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL-m (NCT05315310)
- Testing
- Soft Exosuit
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston University Charles River Campus
Spinal Cord Injuries, Paraplegia
Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
Many people with spinal cord injury (SCI) retain at least some movement below their injury, but their muscles often have a 'mind of their own'.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paraparesis
- Trial name
- NCT01740128
- Testing
- Robotic body weight supported treadmill training, Harness-supported multimodal balance training
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Old Age; Debility
Older People Gait: Physiomechanics and Functionality
The aim of study is to investigate gait in active elderly people regarding the kinematic parameters of gait, indicators of physical fitness and quality of life.
- Trial name
- NCT04348539
- Testing
- Balance training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Stroke
Robotic Exosuit Augmented Locomotion (REAL)
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL (NCT04818424)
- Testing
- Soft exosuit, Gait training without exosuits
- Where
- 3 sites in United States
- Sponsor
- Lou Awad, PT, DPT, PhD
Mobility Impairment, Community Dwelling Older Adults
Motor Imagery and Turning Practice to Improve Mobility: Pilot Trial
The goal of this clinical trial is to evaluate whether combining in-person turning practice with home-based Motor Imagery Therapy (MIT) is feasible and may improve mobility in community-dwelling older adults aged 65 years and…
- Trial name
- MI-TURN (NCT07705360)
- Testing
- Motor Imagery Therapy, Stress Management Education, Locomotor Turning Practice
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boise State University
Hand Surgery, Wrist Surgery
Early Rehabilitation After Hand or Wrist Ambulatory Surgery : How to Preserve Locomotion at Home Without Rebound Pain?
The purpose of this retrospective study is to compare the analgesic efficacy of Walant " Wide Awake Local Anesthesia No Tourniquet " with lidocaine and bupivacaine versus axillary brachial plexus block using mepivacaïne, both…
- Trial name
- WalantBAX (NCT04306666)
- Testing
- Regional anesthesia
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Gait, Balance
Sensor Ankle Brace for Special Operations Rehabilitation
The primary purpose of this study overall is to validate a modified version of a commercially available ankle brace. Inertial measurement unit sensors will be incorporated into an existing ankle brace ("sXAB") by TayCo Brace…
- Conditions
- Gait, Balance, Biomechanical Data, Postural Control
- Trial name
- NCT07776223
- Testing
- Sensor-enabled Athletic X Ankle Brace (sXAB)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Exoskeleton Device, Locomotion
Investigation of the Effects of Robot Assisted Gait Training With Virtual Reality on Cognitive Functions in Stroke Patients
It was planned to examine the effects of robot-assisted walking training supported by virtual reality on cognitive functions, quality of life and activities of daily living in individuals with subacute stroke.
- Conditions
- Exoskeleton Device, Locomotion, Stroke
- Trial name
- NCT05614141
- Testing
- Lokomat Augmented Performance Feedback, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara Yildirim Beyazıt University
Multiple Sclerosis
The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis
Majority of people with multiple sclerosis experience difficulty with balance and mobility, leading to an increased risk of falls.
- Trial name
- NCT05878873
- Testing
- Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Unilateral Amputation of the Lower Limb
Virtual Reality Applied to the Evaluation and Rehabilitation of Locomotion - Study of Tolerance in the Lower Limb Amputee
The adaptability of the locomotor activity allows to face all the modifications of the immediate environment met in the daily activities.
- Trial name
- REVA (NCT05635799)
- Testing
- Analysis of walking on flat ground, Hospital Anxiety Disorder Questionnaire, Analysis of walking on slopes
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Multiple Sclerosis
Biomechanical Characterization of the Locomotion in Multiple Sclerosis Patients
Multiple sclerosis (MS) is an inflammatory chronic disease of the central nervous system. Patients are suffering from balance and gait impairments at the early stage of the disease.
- Trial name
- WALKING-SEP (NCT03756142)
- Testing
- Motion Analysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Brain Concussion, Musculoskeletal Injury
A Sports Injury Prevention Program to Reduce Subsequent Injuries After Concussion
The long-term goal of this research is to implement methods that healthcare providers can use across diverse clinical settings to (1) identify athletes at risk for (musculoskeletal) MSK injury when cleared to return to play (RTP)…
- Conditions
- Brain Concussion, Musculoskeletal Injury, Locomotion, Postural Balance
- Trial name
- NCT03917290
- Testing
- Neuromuscular training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Spinal Cord Injury
Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury
As a first-in-class (Central Pattern Generator or CPG activator) approach, this tritherapy candidate called SPINALON has been identified and is currently under development for its capacity to temporarily induce episodes of…
- Trial name
- NCT01484184
- Testing
- SPINALON (buspirone + levodopa + cardidopa)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nordic Life Science Pipeline Inc.
Spinal Cord Injuries
Improving Gait in Patients With Spinal Cord Injuries
This study is part of a larger clinical trial that examines the potential of a 12-week treadmill-training program to improve walking in patients with spinal cord injuries (SCIs).
- Trial name
- NCT00060983
- Testing
- Body weight supported locomotor training, Functional electrical stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Traumatic Brain Injury, Gait Disorders, Neurologic
Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients
The project will consist of subjects who have suffered Traumatic Brain Injury (TBI) and who are able to ambulate on treadmill with or without a harness system.
- Trial name
- NCT05622786
- Testing
- HIGT - physical rehab, Low intensity physical therapy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic