Clinical trials: Locomotor Activity, active
Gait, Balance
Sensor Ankle Brace for Special Operations Rehabilitation
The primary purpose of this study overall is to validate a modified version of a commercially available ankle brace. Inertial measurement unit sensors will be incorporated into an existing ankle brace ("sXAB") by TayCo Brace…
- Conditions
- Gait, Balance, Biomechanical Data, Postural Control
- Trial name
- NCT07776223
- Testing
- Sensor-enabled Athletic X Ankle Brace (sXAB)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Spinal Cord Injuries
Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury
The loss of movement and walking ability significantly affects quality of life after spinal cord injury. In addition, bladder dysfunction consistently ranks as one of the top disorders affecting quality of life after spinal cord…
- Trial name
- MC-PP-3 (NCT04879862)
- Testing
- Epidural stimulation + Stand Training, Epidural stimulation + Step Training, Epidural stimulation + Bladder Capacity Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Claudia Angeli
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Capsule Endoscopy
Active Locomotion of Magnetically Controlled Capsule Endoscopy in the Small Bowel: A Feasibility Study
The aim of this study is to evaluate the responsiveness of the capsule endoscope to the attitude controller and to investigate its active locomotion performance within the small bowel.
- Trial name
- NCT07325344
- Testing
- magnetic control
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shandong University
Spinal Cord Injuries
Epidural Stimulation and Resistance Training After SCI
Spinal cord injury (SCI) is a devastating health problem for tens of thousands of military personnel, Veterans and civilians annually. Many persons with SCI must use a wheelchair for their entire life.
- Trial name
- REST-SCI (NCT04782947)
- Testing
- Exoskeletal assisted walking, Epidural Stimulation, Resistance Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Department of Defense
Stroke
Virtual Reality and Field Training to Enhance Community Walking After Stroke
While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited.
- Trial name
- NCT04559373
- Testing
- Virtual Reality and Field Training (VRFT)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McGill University
Chronic Hemiparetic Stroke
Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke
Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost…
- Trial name
- NCT06400186
- Testing
- High intensity gait training in varying external environments, Treadmill walking in varying external environments
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Obesity and Overweight
Effect of Simulated Weight Loss on the Energy Cost of Locomotion in Overweight or Obese Adolescents
Current literature suggests that part of the energy response to weight loss is not due to changes in fat mass and lean mass, but rather to a homeostatic adaptation aimed at limiting or even preventing weight loss and preserving…
- Trial name
- DELOAD (NCT07155746)
- Testing
- Incremental walking exercise on an AlterG treadmill (anti-gravity)
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Emile Roux
Lower Limb Amputation
Exploratory Functional Assessment After Lower Limb Amputation: Locomotion, Balance, Energy Performance and Strategies for Adapting to Orthopaedic Devices
The general aim of this exploratory study is therefore to investigate and quantify the functional capacities of patients with lower limb amputations (transtibial and transfemoral), with no change in their management, and to…
- Trial name
- AMILOCO (NCT07094074)
- Testing
- Walk tests, Functional testing, Balance analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Amputation
Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs
The overall goal of this project is to model human joint biomechanics over continuously-varying locomotion to enable adaptive control of powered above-knee prostheses.
- Trial name
- NCT06138977
- Testing
- Powered prosthesis
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Older Adults
Aging and Mixed Perturbation Training to Reduce Falls in Locomotion
The long-term objective of this research is to develop an efficacious training paradigm to enhance older adults' defense mechanisms against falls and possibility reduce healthcare cost.
- Trial name
- NCT03199729
- Testing
- Slip-only training, Trip-only training, Combined slip+trip training
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Spinal Cord Injuries, Neurogenic Bladder
Pediatric Locomotor Training Bladder Study
Bladder dysfunction is one of the most important factors influencing duration and quality of life in children with spinal cord injury.
- Trial name
- NCT03559036
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Stroke
Constraint Induced Movement Therapy for Walking in Individuals Post Stroke
To compare the effect of constraint induced movement therapy (CIMT) vs. treadmill training only on walking function in individuals post-stroke, a 6 week, single-blind, randomized training study will be conducted with three…
- Trial name
- NCT03264261
- Testing
- robotic training, treadmill training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shirley Ryan AbilityLab
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Spinal Cord Injuries
Transcutaneous Spinal Stimulation and Exercise for Locomotion
Growing evidence indicates that electrical spinal cord stimulation improves motor functions both immediately and over the long term via modulating the excitability of spinal circuitry in patients with spinal cord injury.
- Trial name
- NCT03509558
- Testing
- Transcutaneous spinal stimulation, Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Cerebral Palsy (CP)
Activities-based Locomotor Training in Children With Cerebral Palsy
This project aims to improve the quality of life and functional outcomes for young non-ambulatory children with Cerebral Palsy (CP) by investigating the efficacy of an Activities-Based Locomotor Training (AB-LT) program compared…
- Trial name
- ENGAGE-CP (NCT07184411)
- Testing
- Activities-based locomotor training, physical therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor University
Movement Disorders, Neurorehabilitation
Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants
Participants will perform experiments with non-invasive activity recordings. The study will record from multiple non-invasive signal sources that reflect motor intent that may include: electroencephalography (EEG)…
- Conditions
- Movement Disorders, Neurorehabilitation, Non-invasive Activity Recording
- Trial name
- NCT07236892
- Testing
- Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Lower Limb Amputation
Identification of Limiting Factors in the Locomotor Activity of Individuals With Lower Limb Amputation:
The experience of amputation leads to a deterioration in quality of life, with undeniable somatic and functional repercussions. The result is a reduction in general mobility, increased metabolic energy requirements and a feeling…
- Trial name
- AMPUTEEFACT (NCT06415955)
- Testing
- None, pure observationnal study
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Spinal Cord Injury
Xo-Motion R Exoskeleton in SCI-Adoption Study
After spinal cord injury (SCI), many people lose their ability to walk and do not have access to equipment and assistance that could help them regain functional abilities.
- Trial name
- NCT07380516
- Testing
- XoMotionR- assisted locomotor training
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta