Clinical trials: Locoregional Anaesthesia
Pain, Postoperative
Long-acting Local Vaginal Cuff Anesthesia Following Hysterectomy
The purpose of this study is to compare recovery unit and post operation day (POD) 1 pain score in women following elective robotic assisted TLH (RA-TLH) for benign indication with and without local vaginal cuff injection of…
- Trial name
- LAVA (NCT07842159)
- Testing
- Combined Bupivacaine and Exparel, Normal Saline (NS)
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- The University of Texas Health Science Center, Houston
Perioperative Analgesia, Hip Dislocation, Developmental
PENG Block in Comparison With FICB for Hip Reconstruction in Children
The goal of this clinical trial is to test the hypothesis that performing a Pericapsular nerve group (PENG) block allows for more effective analgesia in the perioperative period during reconstructive surgery on the hip in…
- Trial name
- NCT06210503
- Testing
- Pericapcelar group nerve block, Fascia iliaca compartment block
- Where
- Russia
- Volunteers
- 86 people
- Sponsor
- Saint Petersburg State University, Russia
Osteoarthritis, Hip
3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Spinal anesthesia is commonly utilized for hip replacement surgery. Different medications used for spinal anesthesia work for different lengths of time.
- Trial name
- NCT03948386
- Testing
- isobaric bupivacaine, hyperbaric bupivacaine, isobaric mepivacaine
- Where
- 2 sites in United States
- Volunteers
- 159 people
- Sponsor
- Thomas Jefferson University
PONV
Prophylactic Antiemetic Efficacy of Palonosetron Versus Ondansetron for Cesarean Sections Under Regional Anesthesia
This study aims to compare the quality of perioperative antiemesis of palonosetron and ondansetron in patients undergoing cesarean section
- Trial name
- PONV (NCT02468323)
- Testing
- Ondansetron, Palonosetron
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital de Base
Tourniquet-induced Pain, Procedural Pain
Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia.
- Trial name
- NCT07878962
- Testing
- Dexmedetomidine, ketorolac, Lidocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Mayo Hospital Lahore
Anesthesia, Local
Phentolamine Mesylate as a Reversal of Local Anesthesics
Oraverse © (Phentolamine mesylate) is a product designed to reverse the effect of local anesthetics used in dentistry. Its main objective is to reduce the postoperative period during which the patient suffers from the lack of…
- Trial name
- NCT03740386
- Testing
- Phentolamine Mesylate 0.235 MG/ML [OraVerse]
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- León Formación
Frozen Shoulder, Adhesive Capsulitis of the Shoulder
Local Anesthesia While Awake Versus General Anesthesia for Frozen Shoulder Manipulation
This study compared two anesthesia approaches for shoulder manipulation in adults with primary frozen shoulder that had not improved after at least 6 months of conservative treatment.
- Trial name
- NCT07731646
- Testing
- Ultrasound-Guided WALANT-Based Shoulder Manipulation, Shoulder Manipulation Under General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Izmir Katip Celebi University
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Surgery of Abdominoplasty With Flank Liposuction
Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of…
- Trial name
- NCT01862354
- Testing
- Transverse abdominal plan block, Continuous wound infusion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Fibromyalgia
Phrenic Nerve Infiltration in Fibromyalgia
It is known that nociceptive afferences in visceral pain and visceral disorders increase sensitization in subjects suffering from fibromyalgia. These patients use to present visceral comorbidities.
- Trial name
- NCT05792774
- Testing
- Bupivacain
- Where
- 4 sites in Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Appendectomy, Laparoscopic, Appendicitis Acute
Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic Appendectomy
The aim of this prospective, randomized study is to evaluate the effects of two different specimen extraction sites (periumbilical versus left lower quadrant) and the routine application of port-site local anesthesia infiltration…
- Conditions
- Appendectomy, Laparoscopic, Appendicitis Acute, Pain Management
- Trial name
- NCT07824908
- Testing
- Port-site local anesthesia infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- YUNUS YÜKSEL
Bowel Disease
Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy
This study will be a single center, prospective triple blinded randomized controlled study, comparing the use of liposomal bupivacaine (Exparel) to regular bupivacaine with adjuncts in bilateral mid-abdominal transverse abdominis…
- Trial name
- TAPLIP (NCT05224089)
- Testing
- Liposomal Bupivicaine/Bupivacaine Admixture, Bupivacaine HCL
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Hartford Hospital
Regional Anesthesia, Pain, Postoperative
Analgesic Efficacy of Single-shot Erector Spinae Block for Thoracic Surgery
The erector spinae plane (ESP) block is a novel regional anesthetic technique for the treatment of thoracic, cervical, and abdominal pain.
- Trial name
- AnESTh (NCT03419117)
- Testing
- ESP block
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dental Pain and Sensation Disorder, Anesthesia, Local
Impact of Tramadol Addiction On Dental Anesthesia Success
The aim is to investigate and to find a correlation between tramadol addiction misuse among Algerian males and Dental Local Anesthesia success while performing dental care and oral surgeries.
- Conditions
- Dental Pain and Sensation Disorder, Anesthesia, Local, Addiction, Opioid
- Trial name
- NCT05908305
- Testing
- articaine@ (4% 1:100000 epinephrine) dental anesthesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Algiers
Anxiety
Virtual Reality to Reduce Intraoperative Anxiety in Vasectomies Under Local Anesthesia
Vasectomy is an elective and ambulatory surgery, typically performed under local anaesthesia. The most common problem that we have found among patients is the anxiety and the apprehension to face the procedure.
- Trial name
- NCT06749353
- Testing
- Virtual reality
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Hospital Mutua de Terrassa
Breast Cancer, Postoperative Pain
PECS Block in Partial Mastectomy for Postoperative Pain Control
The aim of this study is to evaluate patients who are undergoing partial mastectomy or removal of breast tissue and see if a pectoralis nerve block (PECS) can provide a meaningful improvement in postoperative pain control over…
- Conditions
- Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
- Trial name
- PECS (NCT04086394)
- Testing
- Pectoral Nerve Block, Surgery without Nerve Block
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Main Line Health
Hernias Inguinal Reducible, Local Anaesthesia
Comparison Between Desarda and Lichtenstein's Technique for Inguinal Hernia Repair Under Local Anaesthesia
Inguinal hernia repair is done by two methods. The conventional method uses a prosthetic mesh for strengthening the defect but has been associated with complications.
- Trial name
- NCT03512366
- Testing
- Desarda's technique, Lichtenstein's technique
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Orthopedic Disorders, Foot Diseases
Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), requires a shorter time to develop surgical anesthesia of the lower leg.
- Conditions
- Orthopedic Disorders, Foot Diseases, Injuries, Leg, Injuries, Foot
- Trial name
- NCT01999647
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Parma
Sevoflurane Consumption
Pre-emptive Local Anesthesia and Sevoflurane Consumption in Pediatric Dental Anesthesia
This study will evaluate whether pre-emptive local anesthesia reduces sevoflurane consumption during pediatric day-case dental treatment performed under general anesthesia.
- Trial name
- PEDSEVOLA (NCT07608900)
- Testing
- Pre-emptive Local Anesthesia, Articaine With Epinephrine, Sevoflurane
- Volunteers
- 80 people
- Sponsor
- TC Erciyes University
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