Clinical trials: Locoregional Anaesthesia
Diaphragmatic Excursion, Hemidiaphragmatic Paralysis
Diaphragmatic Effects of Combined Infraclavicular Brachial Plexus Block and Suprascapular Nerve Block
This prospective observational study was conducted to evaluate the effects of a combined infraclavicular brachial plexus block and anterior suprascapular nerve block on diaphragmatic function in patients undergoing arthroscopic…
- Conditions
- Diaphragmatic Excursion, Hemidiaphragmatic Paralysis, Arthroscopic Shoulder Surgery
- Trial name
- ICB-SNB (NCT07640464)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Gazi University
Anesthesia, Tubal Ligation
Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
This study compares general anesthesia and spinal anesthesia for vNOTE tubal sterilization. A direct comparison of these methods has not been done before for this surgical approach.
- Trial name
- NCT05688943
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Anesthesia, General
Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly
Laryngeal mask airway (LMA) is currently the most widely used supraglottic airway device with advantages of simple and fast placement, reduced anesthesia drug use, more stable hemodynamics, and less throat discomfort after…
- Trial name
- LMA (NCT05310110)
- Testing
- 10% lidocaine spray, Cisatracurium, Propofol
- Where
- Taiwan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Transversus Abdominis Plane Block, Quoadratus Lumborum Block
Transversus Abdominis Plane Block Versus Quoadratus Lumborum Block on Infants
we aimed to compare the effects of TAPB and QLB on postoperative pain score and analgesic consumption in infants who underwent unilateral inguinal hernia surgery.
- Trial name
- NCT04927624
- Testing
- transversus abdominis plane block, quoadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Arthroplasty, Knee Osteoarthritis
Suprainguinal Fascia Iliaca Block vs. Adductor Canal Block for Analgesia After Total Knee Arthroplasty
This study evaluates the analgesic efficacy and motor-sparing properties of ultrasound-guided Suprainguinal Fascia Iliaca Block (S-FIB) compared with Adductor Canal Block (ACB) in patients undergoing primary total knee…
- Trial name
- NCT07739108
- Testing
- PCA
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pain
The Effects of Injection Site Cooling and Solution Buffering on Perceived Pain During Local Anesthesia Administration
Participants will have local anesthesia administered to the palmar aspect of both forearms using 4 different injection methods in order to determine which method provides the best results in terms of perceived pain, overall…
- Trial name
- NCT04991597
- Testing
- Cold Compress Pack, Room Temperature Compress Pack, Lidocaine Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nicholas Bastidas
Cesarean Section
Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section
The purpose of this randomized double-blind study is to evaluate in which anatomical layer (AF versus BF) continuous wound infusion of local anesthetics combined with NSAIDs through a multiorifice catheter has the best…
- Trial name
- NCT01160913
- Testing
- Continuous wound infusion, Continuous wound
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Association pour la Recherche et la Formation en Anesthésie Analgésie Réanimation
Analgesia
IPACK or Selective Tibial Nerve Block for ACL Reconstruction With an Adductor Canal Block
The purpose of this study is to compare the analgesic efficacy of the combination of an adductor canal and selective tibial nerve blocks versus adductor canal block and IPACK after ACL reconstruction under general anaesthesia.
- Trial name
- TIPACK (NCT05303233)
- Testing
- Selective tibial nerve block, IPACK
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Diabetic Polyneuropathy
Peripheral Nerve Stimulation in Diabetic Patients
The prevalence of diabetes mellitus (DM) in industrialized countries is estimated to be about 7.3% and its incidence has been growing in recent years.
- Trial name
- NCT01488474
- Testing
- peripheral nerve stimulation
- Where
- Austria
- Volunteers
- 124 people
- Sponsor
- Medical University of Graz
Oral Lichen Planus, Periodontal Diseases
Periodontal Initial Treatment Combined With Glucocorticoid Therapy for Erosive Oral Lichen Planus
The purpose of this clinical trial is to understand whether the combination of periodontal initial treatment under local anesthesia and glucocorticoids can improve the effectiveness of treatment for erosive oral lichen planus.
- Trial name
- NCT06498180
- Testing
- Periodontal initial treatment under local anesthesia, Glucocorticoid Therapy, oral hygiene instruction
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Rectal Prolapse
Endoluminal and Needlescopic Assisted Repair of Rectal Prolapse
The purpose of this study is to evaluate the safety and feasibility of endoluminal rectal prolapse repair under sedation and local anesthesia using CO2 colonoscopy to fix the rectum with sutures to the abdominal wall under…
- Trial name
- NCT01980043
- Testing
- endoluminal rectal prolapse repair under sedation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weill Medical College of Cornell University
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Post Operative Pain
Evaluation of Adding Magnesium Sulfate to (Fentanyl/Bupivacaine)Bi-mixture in Caudal Block
this is a randomized controlled study ,patients will be randomly divided into 2 groups , Group A will receive caudal block using 1ml/kg Bupivacaine +0.5u/kg fentanyl, Group B will receive caudal block 50 mg magnesium sulfate…
- Trial name
- NCT06162806
- Testing
- ultrasound guided caudal epidural block using 1ml/kg of Bupivacaine 0.25% + 0.5microgram/kg of Fentanyl, ultrasound guided caudal epidural block using 50 mg of Magnesium sulfate added to(1ml/kg of Bupivacaine 0.25% + 0.5microgram/kg of Fentanyl)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative Pain, Thyroid Diseases
Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery
The purpose of this study is to compare the efficacy of Bupivicaine and Lidocaine for postoperative pain control in thyroid surgery.
- Conditions
- Postoperative Pain, Thyroid Diseases, Anesthesia, Local
- Trial name
- NCT04427904
- Testing
- Bupivacaine 0.5% with 1:200 000 epinephrine, Lidocaine 2% with 1:100 000 epinephrine
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Labor Pain, Delivery Complication
Effect of Epidural Analgesia on Labour, Neonatal and Maternal Outcomes.
Lumbar epidural analgesia is the most used method for reducing labour pain, but its impact on the duration of the second stage of labour and on neonatal and maternal outcomes remains debated.
- Conditions
- Labor Pain, Delivery Complication, Regional Anesthesia Morbidity
- Trial name
- NCT05579808
- Testing
- Epidural Analgesia
- Where
- Italy
- Volunteers
- 21,808 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diseases of Mitral Valve, Aortic Valve Disorder
Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery
The purpose of this study is to examine the wound infusion of articaine for treatment of acute post-sternotomy pain in a placebo-controlled manner using a prospective and randomized design and an active control (bupivacaine)
- Conditions
- Diseases of Mitral Valve, Aortic Valve Disorder, Atrial Septal Defects, Intracardiac Myxoma
- Trial name
- NCT01536717
- Testing
- Articaine hydrochloride 2% solution, Sodium Chloride
- Where
- 2 sites in Finland
- Volunteers
- 36 people
- Sponsor
- Helsinki University Central Hospital
Regional Anesthesia
Evaluation of ChatGPT-4's Success Sonoanatomy
Aim and Importance: Regional anesthesia techniques have advanced significantly with the advent of ultrasound guidance. Peripheral nerve blocks and fascial plane blocks can now be performed safely and effectively under ultrasound…
- Trial name
- NCT06642389
- Testing
- Sonoanatomical Structure Identification, Block Type Prediction, Block Success Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
Limb Deformity
Analgesic Efficacy of Two Doses of Dexmedetomidine as Adjuncts to Lidocaine for Intravenous Regional Anesthesia
Intravenous Regional Anesthesia (IVRA) was first used by August Bier in 1908. This technique is easy to administer, reliable and cost-effective for short surgical procedures of the extremities performed on an ambulatory basis…
- Trial name
- NCT03399474
- Testing
- Lidocaine Hydrochloride 2%, Dexmedetomidine 0.5 ug/kg, Dexmedetomidine Injection 0.25 ug/kg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
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