Clinical trials: Locoregional Anaesthesia
Endodontic Inflammation
Comparison of Osteocentral Versus Locoregional Anesthesia in Case of Mandibular Molar Pulpitis
The irreversible acute pulpitis is the most common emergency at the hospital during dental consultation. Pulpitis are characterized by intense and spontaneous oro-facial pains.
- Trial name
- COQ (NCT03802305)
- Testing
- computerized intraosseous technique (Quicksleeper™), loco-regional anesthesia (IANB technique)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Nantes University Hospital
Regional Anesthesia Morbidity
Safety of Regional Anesthesia in Ukraine: the Survey
The common using of ultrasound navigation makes an opportunity to develop the regional anesthesia. Regional anesthesia reduces the length of stay in the hospital, reduces the intensity of perioperative pain and decrease opioid…
- Trial name
- NCT05478629
- Testing
- Survey
- Where
- Ukraine
- Volunteers
- 182 people
- Sponsor
- Bogomolets National Medical University
Breast Cancer, Pain, Postoperative
Erector Spinae Plane Block Versus Paravertebral Block
This study aims to compare the effectiveness of paravertebral block and erector spinae plane block after mastectomy. The primary objective of this randomized controlled trial is to demonstrate equivalent dermatomal spread for…
- Conditions
- Breast Cancer, Pain, Postoperative, Anesthesia, Local
- Trial name
- NCT03471442
- Testing
- Paravertebral block, Erector spinae plane block, General anesthetic
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Shoulder Surgery, Regional Anesthesia Morbidity
Comparison Between Interscalene and Combined Costoclavicular-suprascapular Blocks for Arthroscopic Shoulder Surgery
Postoperative analgesia for shoulder surgery is typically achieved by providing an interscalene brachial plexus block. However, a very common side effect of this block is hemi-diaphragmatic paralysis, a state which may not be…
- Trial name
- NCT04224766
- Testing
- Suprascapular Nerve Block with 5ml bupivicaine 0.5%, costoclavicular Block 10ml bupivicaine 0.5%, Interscalene Brachial Plexus Block 15ml bupivicaine 0.5%
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Primary Spontaneous Pneumothorax
Comparative Study of Nonintubated Anesthesia Versus Intubated General Anesthesia in Single Port Thoracoscopic Bullectomy
Investigators compared the patients' subjective postoperative symptoms and complications between the double lumen endotracheal intubated patients under general anesthesia and non-intubated patients under sedation and local…
- Trial name
- NCT02109510
- Testing
- nonintubated sedation anesthesia with dexmedetomidine IV, ketamine IV and intercostal nerve block with lidocaine infiltration, intubated general anesthesia with propofol IV, rocuronium IV ,sevoflurane and N2O gas, single port thoracoscopic bullectomy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University
Anesthesia, Local
Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine
Assess the clinical impact of Buffered 1% lidocaine with epinephrine as compared to the Non-buffered 1% lidocaine with epinephrine in dental and oral surgical procedures.
- Trial name
- NCT03127943
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Local Anesthesia, Dental Anesthesia
Effect of Pre-Warming of Local Anesthesia in Reducing Pain Perception During Injection in Children
The aim of the current study was to evaluate the pain perception upon injection of pre-warmed dental anesthetic solution (at 370C and 400C) versus that at room temperature (Average 23 degrees) during Maxillary Infiltration and…
- Trial name
- NCT06519838
- Testing
- Local anesthesia solution at room temperature, Local anesthesia solution pre-warmed to 37°C, Local anesthesia solution pre-warmed to 40°C
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Andrew Emad
Anesthesia, Local
A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution
A Phase 3, randomized, placebo-controlled, double-masked, parallel study in healthy subjects. It is designed to evaluate the ocular safety of a single topical ocular administration of AG-920 sterile topical ophthalmic solution…
- Trial name
- NCT05501860
- Testing
- AG-920
- Where
- 2 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Virtual Reality Simulation, Virtual Reality
RA Anatomy - VRvST Study
Primary Objective: Score out of 44 on a validated test of anatomy and sono-anatomy Secondary Objective: Before training Handedness (Edinburgh Handedness Inventory) Subjective sleepiness (Karolinska scale) Motor reaction time…
- Conditions
- Virtual Reality Simulation, Virtual Reality, Education, Medical
- Trial name
- NCT07361913
- Testing
- 3D virtual reality anatomy teaching, Standard anatomy model teaching
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Primary Inguinal Hernia
The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP)
The study is devoted to the impact of preemptive regional Transversus abdominal plane block on the postoperative acute and chronic pain after elective Transabdominal preperitoneal (TAPP) inguinal hernia repair.
- Trial name
- ERA-TAPP (NCT06406959)
- Testing
- Transversus abdominal plane block (TAP block)
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- Pirogov Russian National Research Medical University
Regional Anesthesia
Retrospective Evaluation of Effect of Anterior Iliac Block
In this study, the investigators aimed to evaluate the effect of ultrasound-guided anterior iliac block which was performed preoperatively. Anterior iliac bone harvesting is associated with severe postoperative pain.
- Trial name
- NCT06295224
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Kocaeli University
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Regional Anesthesia, Carotid Endarterectomy
Hemi-diaphragmatic Paresis After Erector Spinae Plane Block
To assess the incidence of hemi-diaphragmatic paresis following ultrasound-guided erector spinae plane (ESP) block
- Trial name
- NCT04706780
- Testing
- ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Antalya Training and Research Hospital
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Obstetric Anaesthesia With Cardiac Complications
A Superior Anesthetic Technique for the Cesarean Section From a Hemodynamic Perspective.
Cesarean section operations are increasing in rates worldwide. A proper anesthetic technique is required to maintain the safety of both the mother and the fetus.
- Trial name
- NCT04989270
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Oman
- Volunteers
- 2,500 people
- Sponsor
- Sultan Qaboos University
Dental Anxiety, Pain
Pain and Anxiety Levels of Sleeperone Electronic Anesthesia System in Pediatric Patients
The conventional method used for dental anesthesia in children is the administration of a local anesthetic solution by injection.
- Trial name
- NCT06340022
- Testing
- Children's Fear Survey Schedule-Dental Subscale (CFSS-DS) scale, Face Image Scale (FIS) scoring system, Visual Analogue Scale (VAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Chronic Pain, Recurrences
Comparison of Three Meshes in Lichtenstein Hernia Repair
Chronic pain may be a long-term problem after inguinal Lichtenstein hernioplasty. The aim of this study was to compare long-term results of hernioplasty using three different meshes (partly absorbable, lightweight polypropylene…
- Trial name
- Lichtenstein (NCT01295437)
- Testing
- Vypro II mesh, Premilene LP, Premilene mesh
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Anesthesia, Local
Risk Factors of Inferior Alveolar Nerve Block Failure: a Dental Student-centered Study
Inferior alveolar nerve block anesthesia is one of the most commonly used regional block anesthesia in dentistry. The factors that determine the success of this type of anesthesia which is applied so frequently, are not reported…
- Trial name
- NCT05681546
- Where
- Turkey (Türkiye)
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Postdural Puncture Headache
Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache
PDPH is a common problem after either intentional or unintentional Dural puncture. It is especially common in young female patients and in patients undergoing Lumbar Puncture using the typical kit containing large 20 gauge…
- Trial name
- PDPH (NCT02394457)
- Testing
- Cosyntropin, Epidural Blood Patch
- Volunteers
- 29 people
- Sponsor
- United States Naval Medical Center, San Diego
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
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