Clinical trials: Locoregional Anaesthesia
Virtual Reality, Anesthesia, Local
Efficacy of VR Distraction During Local Anesthesia in Children
The aim of this study is to compare between active distraction (video game) and passive distraction (cartoon video) using a Virtual Reality ( VR ) device, in reducing injection pain and anxiety associated with local anesthesia in…
- Conditions
- Virtual Reality, Anesthesia, Local, Pain
- Trial name
- NCT05129943
- Testing
- active distraction, passive distraction
- Where
- Syria
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Latakia University
Varicocele, Postoperative Pain
The Effect of Subcutaneous and Intraperitoneal Anesthesia on Post Laparoscopic Pain
Aim of this study is to examine the effects of subcutaneously applied local anesthetics at trocar site in combination with intraoperative intraperitoneal analgesia on duration and character of pain in pediatric patients…
- Trial name
- NCT05034406
- Testing
- 2% Lidocaine, 0.5% levobupivacaine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- KBC Split
Anesthesia, Local
Comparing Analgesic Effects of Caudal and Erector Spinae Plane Blocks in Pediatrics Undergoing Upper Abdominal Surgery
Upper abdominal surgeries are painful and pediatric patients who undergo these operations require effective postoperative pain control.
- Trial name
- NCT04204343
- Testing
- Bupivacaine 0.7 ml/kg, Bupivacaine 0.5 ml/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Comparison of Buffered Versus Non Buffered Local Anesthetic In Inflamed Tissues
"Comparison of Buffered Versus Non-Buffered Local Anesthetic in Patients With Inflamed Tissues for Pain Perception, Onset, Duration and Adverse Effects"
This study aims to determine whether buffered or non-buffered local anesthetic (LA) is more effective and safer for managing pain in patients with inflamed tissues undergoing surgical procedures.
- Trial name
- NCT07592143
- Testing
- Buffered Local Anesthesia
- Volunteers
- 68 people
- Sponsor
- King Edward Medical University
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Regional Anesthesia, Regional Anesthesia Block
Neurological Events and Unforeseen Risks After Locoregional-anesthesia
This is a multicenter, prospective, observational study aimed at determining the incidence of neurological and non-neurological complications following locoregional anesthesia procedures.
- Trial name
- NEURAL (NCT07238933)
- Testing
- Observational assessment after regional anesthesia
- Where
- 4 sites in Italy
- Volunteers
- 3,396 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Hernia, Anesthetics Adverse Reaction
Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial
This present randomized trial is designed to evaluate the postoperative pain,inflammatory marker, postoperative analgesic medication, length of hospital stay and the modifications of inflammatory mediators in patients undergoing…
- Conditions
- Hernia, Anesthetics Adverse Reaction, Inflammation
- Trial name
- NCT01845376
- Testing
- local anesthesia group, spinal anesthesia group, general anesthesia group
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Mingkwan Wongyingsinn, MD
Irreversible Pulpitis
Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars
The purpose of this trial is to study the ability of a frequently used dental anesthetic (articaine) to achieve complete numbness of a diseased tooth with the most commonly used injection technique in the lower jaw (inferior…
- Trial name
- ARTIC (NCT01496846)
- Testing
- IANB Articaine, SUP Articaine, SUP Lidocaine
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Michigan
Wisdom Teeth Extraction or Jaw Implant
Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia
Tooth extraction is one of the most common procedures in dentistry. Surgical extraction of damaged wisdom teeth involves bone resection and injury to the soft tissue.
- Trial name
- NCT06380608
- Testing
- Local anesthesia, General anesthesia
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Zoya Haitov Ben Zikri
Peripheral Artery Occlusive Disease, Percutaneous Transluminal Angioplasty
Regional Anesthesia for Percutaneous Transluminal Angioplasty
In this study, the effects of regional anesthesia method applied in patients who will undergo percutaneous transluminal angioplasty for lower extremity revascularization will be investigated comparatively.
- Trial name
- NCT05737225
- Testing
- Near Infrared Spectroscopy (NIRS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gazi University
Urinary Stress Incontinence
Safety and Efficacy Study on the Implantation of the Tension-Free Vaginal Tape (TVT-Secur) Under Local Anesthesia
The objective was to observe the satisfaction of local anesthesia during the implantation of the TVT-SECUR for the treatment of stress urinary incontinence, with the use of questionnaires completed by the patients, and to…
- Trial name
- NCT00904618
- Testing
- TVT-SECUR - 'Hammock' technique, TVT-SECUR - 'U-Method', Local anesthesia (30 to 40 ml of a mixture of 35 ml of lidocaine 2% and 5 ml of bicarbonate 3%).
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Anaesthesia, Cataract
A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at Kaduna, Nigeria
The aim of the study was to compare the efficacy and safety of single injection peribulbar anaesthesia against the classic double injection technique.
- Trial name
- NCT02150460
- Testing
- One-site peribulbar injection, Two- site peribulbar injection
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Eye Centre, Kaduna
Glaucoma
Dexmedetomidine as an Additive to Local Anaesthesia to Decrease Intraocular Pressure in Glaucoma Surgery
Nowadays, a number of cases with increased intraocular pressure and glaucoma have been shown a huge increase . This is because of the increase the geriatric population in the community and advanced medical care.
- Trial name
- NCT02846090
- Testing
- Dexmedetomidine to reduce the IOP
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Postoperative Pain, Surgery
Local Anesthesia Versus Saline Serum in Surgical Incision of Colorectal or Hepatic Surgery
The purpose of this study is to determine whether a continuous infusion of local anesthesia with a catheter in the surgical wound reduces patient consumption of opiates by 30% in the 48-hour postoperative period following surgery…
- Conditions
- Postoperative Pain, Surgery, Postoperative Complications
- Trial name
- CATROP-2007 (NCT01075646)
- Testing
- ropivacaine, saline solution
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Hospital Universitari de Bellvitge
Pain
Comparison of Physical Versus Visual Distraction in the Reduction of Pain During Local Anesthesia
The purpose of this study is to compare physical versus visual distractions to determine which technique reduces perceived pain better during local anesthesia injections.
- Trial name
- NCT04595721
- Testing
- Hidden object, Stress ball
- Sponsor
- Virginia Commonwealth University
Surgery
Analgesic Efficacy of Intravenous Dexmedetomidine for Supraclavicular Plexus Block
The goal of the study is to compare the duration of analgesia in patients undergoing forearm or hand surgery with a supraclavicular brachial plexus block, who receive either iv dexmedetomidine or placebo.
- Trial name
- TwoDex (NCT05389852)
- Testing
- Dexmedetomidine
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital du Valais
Opioid Use
Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery
This study aims to assess the impact of bilateral deep parasternal intercostal plane block on intraoperative opioid consumption in open heart surgery
- Trial name
- NCT05103787
- Testing
- deep parasternal intercostal plane block, control
- Where
- 2 sites in Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Prostate Cancer
Feasibility of Virtual Reality Assistance in Prostate Biopsy Under Local Anesthesia.
The goal of this clinical trial is to test the impact of Virtual Reality (VR) assistance for anxiety management of patients undergoing prostate biopsies in local anaesthesia.
- Trial name
- NCT06274684
- Testing
- Use of Virtual Reality Assistance during prostate biopsies
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Osteoarthritis, Knee
Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA
To evaluate the efficacy and safety of different doses of triamcinolone for local infiltration analgesia during total knee replacement
- Trial name
- LIA;TKA (NCT05997238)
- Testing
- without triamcinolone, 20mg triamcinolone, 40mg triamcinolone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Regional Anaesthesia, Transversus Abdominis Plane Block
Prospective, Randomized Comparative Study Between an Anesthesiological, Ultrasound-guided, and a Laparoscopic, Landmark-based Application of a "Transversus Abdominis Plane (TAP) Block" Based on Postoperative Pain Perception, Postoperative Analgesic Requirement, and Procedure Duration
The Transversus Abdominis Plane Block (TAP) has become one of the most established and frequently performed trunk wall blocks for perioperative analgesia in abdominal surgical procedures.
- Trial name
- NCT06876155
- Testing
- Arm 1: The anaesthesiologically performed, ultrasound-guided, 4 quadrant-TAP block ( a combination of a lateral with a subcostal TAP block bilaterally), Arm2: The surgically performed, laparoscopic landmark-based assisted TAP block
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Sana Klinikum Offenbach
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