Clinical trials: Locoregional Anaesthesia
Gastric Cancer, Postoperative Pain
Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy
This study is a single-center, prospective, randomized controlled trial designed to compare two established postoperative analgesic strategies in adult patients undergoing laparoscopic gastrectomy under general anesthesia.
- Trial name
- TAP-WELPASS (NCT07452471)
- Testing
- Ultrasound-guided Transversus Abdominis Plane (TAP) Block, Ropivacaine-Poloxamer 407 Hydrogel (Welpass®)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gyeong-Jo Byeon, MD, PhD
Anesthesia, Adductor Canal Block
Location of Injection of Local Anesthetics in the Adductor Canal Block
The adductor canal block (ACB) is the standard of care for analgesia after Anterior Cruciate Ligament (ACL) repair. ACB is performed by injecting local anesthetic (freezing) in the subsartorial canal in the thigh which is about…
- Trial name
- LILAC (NCT02554864)
- Testing
- lidocaine, ropivacaine
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Women's College Hospital
Regional Anesthesia, Regional Anesthesia Morbidity
Impact of Communication Delays on Anesthesia Response to Medical Emergencies and Ultrasound-Guided Regional Anesthesia
Hypotheses The investigators hypothesize that a communication delay of 80 seconds compared to no delay will be associated with longer procedural times and decreased quality during brachial plexus block scanning.
- Conditions
- Regional Anesthesia, Regional Anesthesia Morbidity, Regional Anesthesia Success, Remote Consultation, Teleconsultation
- Trial name
- ICARUS (NCT07675863)
- Testing
- Real-time communication, Delayed communication
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Regional Anesthesia
Duration of Analgesia in Bier Block for Patients Undergoing Hand Surgery
Intravenous regional anesthesia (Bier block) is widely used as an anesthetic technique for operations of short duration of the distal upper or lower extremities Today, IVRA is still popular in many countries being used in the…
- Trial name
- NCT05578885
- Testing
- Bier block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Michael Bishay Shehata Keroles
Cutaneous Sensory Blockade
Effects of Injection Volume and Site on Sensory Distribution After Rectus Sheath Block
This randomized controlled study aims to evaluate the effects of local anesthetic injection volume and injection site on cutaneous sensory distribution following ultrasound-guided rectus sheath block (RSB).
- Trial name
- RSB-SENSE (NCT07876297)
- Testing
- Ultrasound-Guided Upper Rectus Sheath Block (20 mL), Ultrasound-Guided Upper Rectus Sheath Block (30 mL), Ultrasound-Guided Middle Rectus Sheath Block (20 mL)
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Lower Eyelid Bags
The Effect of Inhalation Aromatherapy on Intraoperative Fear in Patients Undergoing Lower Blepharoplasty Under Local Anesthesia: A Randomized Controlled Trial
This study is a single-center, randomized, controlled, open-label clinical trial designed to evaluate the intervention effect of inhaled aromatherapy on intraoperative fear in patients undergoing lower blepharoplasty (eyelid bag…
- Trial name
- NCT07766902
- Testing
- inhaled aromatherapy
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Aortic Valve Stenosis
RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation
Open-label, 2 x 2 factorial, prospective, randomized, national, multicenter study to compare latest-generation self-expanding valves and a minimalist approach versus standard of care in transcatheter aortic valve implantation.
- Trial name
- DOUBLE-CHOICE (NCT05036018)
- Testing
- ACURATE neo2, minimalist approach, CoreValve Evolut Pro, Pro+ and FX
- Where
- 10 sites in Germany
- Volunteers
- 836 people
- Sponsor
- Leipzig Heart Science gGmbH
Local Anaesthesia
Comparison of the Effects of Two Different Local Anesthetics Used in Spinal Anesthesia
Objective: This study aimed to compare the effects of two different local anesthetics with different baricity used in spinal anesthesia on thermoregulation.
- Trial name
- NCT06763510
- Testing
- Chirocaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Anesthesia, Anesthesia , Analgesia
Artificial Intelligence vs. Automated Messaging for Continuous Regional Analgesia Follow-up
Effective postoperative analgesia is critical for patient recovery, satisfaction, and the reduction of hospital stay duration. Continuous peripheral nerve blocks (CPNB) via catheter placement represent a cornerstone in achieving…
- Conditions
- Anesthesia, Anesthesia , Analgesia, Regional Anesthesia, Regional Anesthesia Success
- Trial name
- NCT07510425
- Testing
- AI-driven follow-up platform, Satisfaction, Adherence to the follow-up protocol
- Where
- Chile
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Carotid Stenosis
Cardiac Output and Duplex Sonography in Carotid Endarterectomy
The aim of this study is to investigate the differences between the cardiac output and the cerebral blood-flow between a regional anesthesia (RA) and a general anesthesia (GA) in a randomized, controlled, single center study at…
- Trial name
- NCT02230358
- Testing
- Regional anesthesia, General anesthesia, Transcranial Doppler ultrasonography
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University Innsbruck
Pain
Topical Local Anaesthesia and Cooling During Capsaicin 8% Patch Application
Aim of the study is to demonstrate superiority of a continuous cooling of the skin over topical EMLA or placebo in reducing the burning pain during the application of capsaicin 8% patch ("Qutenza").
- Trial name
- LACCA (NCT01523951)
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Wide Excision, Postoperative Pain
Local Anesthetic Infiltration for Pain Control After Orthopedic Wide Excision
This study evaluates whether injecting a local anesthetic mixture (ropivacaine, morphine, ketorolac, and epinephrine) under the skin at the incision site before wound closure reduces pain after orthopedic wide excision surgery…
- Trial name
- NCT07753629
- Testing
- Ropivacaine-Morphine-Ketorolac-Epinephrine-Cefuroxime Mixture, Cefuroxime-Saline Mixture
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Thoracic Herpes Zoster
Rhomboid Intercostal and Subserratus Plane Block Versus Paravertebral Block for Thoracic Herpes Zoster
Postherpetic neuralgia (PHN) is a common and debilitating complication of herpes zoster, characterized by persistent and severe pain.
- Trial name
- NCT06751680
- Testing
- Rhomboid Intercostal and Subserratus Plane Block, PVB block
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xiaguang Duan
Arthroscopic Shoulder Surgery
Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block
Interscalene brachial plexus block (ISBPB) is a common nerve block given to patients who are undergoing shoulder surgery. This block has a low, but still significant, rate of complications.
- Trial name
- NCT00731146
- Testing
- Ultrasound Minimum Effective Anesthetic Volume, Nerve Stimulator Minimum Effective Anesthetic Volume
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Airway, Anesthesia, Local
Soft Mist Spray Device for Airway Anaesthesia During Awake Videolaryngoscopy
Rationale: Effective and fast topical anaesthesia of the upper airway is of paramount importance in awake (conscious) videolaryngoscopy of the airway in order to avoid patient discomfort.
- Trial name
- CT2Trachospray (NCT05478122)
- Testing
- Trachospray for awake videolaryngoscopy
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Total Knee Arthroplasty
Comparison of Analgesic Efficiency Between IPACK Block and Surgical Infiltration After Total Knee Arthroplasty
The purpose of this retrospective study is to compare the analgesic efficiency of IPACK block (Interspace between the Popliteal Artery and the Capsule of the posterior Knee) with surgical infiltration after total knee…
- Trial name
- IPACK (NCT03704831)
- Testing
- Injection of local anesthetics during total knee arthroplasty by a locoregional anesthesia named IPACK block, Injection of local anesthetics during total knee arthroplasty by surgical infiltration
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Tuberculosis
Local Anesthesia and Tuberculin Skin Test in Infants and Children
The use of local anaesthesia efficiently reduces pain due to needle puncture. However, when tuberculin skin test is performed it is the skin reaction to tuberculin injection that is studied.
- Trial name
- NCT00309673
- Testing
- lidocaine / Prilocaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Anesthesia, Local, Hand Surgery
Bicarbonate Addition to Lidocaine-Epinephrine in Surgery Under WALANT
Distal upper limb and distal lower limb surgery performed under local anesthesia using the WALANT technique (Wide Awake Local Anesthesia No Tourniquet) has become standard practice in ambulatory orthopedic surgery.
- Conditions
- Anesthesia, Local, Hand Surgery, Foot Surgery, Walant Surgery
- Trial name
- ROPIWA-2 (NCT07342010)
- Testing
- Ambulatory surgery under Lidocaine with epinephrine alone, Ambulatory surgery under lidocaine with epinephrine plus bicarbonate
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
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