Clinical trials: Locoregional Anaesthesia
Chronic Pain
Effect of Intraoperative Infiltration With Bupivacain on the Development of Chronic Pain After Inguinal Hernia Repair
The effect of intraoperative infiltration of the operation site with bupivacain on the development of chronic pain is the object of our trial.
- Trial name
- NCT00484731
- Testing
- Infiltration with Saline, Infiltration with Bupivacaine
- Where
- Switzerland
- Volunteers
- 404 people
- Sponsor
- Luzerner Kantonsspital
Chronic Subdural Hematoma
Outcome of Single Burr Hole Under Local Anaesthesia in the Management of Chronic Subdural Hematoma
Aim of the work: Is to evaluate the prognosis of single burr hole under local anesthesia in management of CSDH according to clinical picture, risk factors, and age.
- Trial name
- NCT03447327
- Testing
- single burr hole
- Volunteers
- 67 people
- Sponsor
- Zagazig University
Pain, Pain Management
Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia.
Breast cancer is the malignant neoplasm with the highest incidence in women in Brazil, with the exception of non-melanoma skin tumors.
- Conditions
- Pain, Pain Management, Anesthesia
- Trial name
- pain (NCT06889870)
- Testing
- Pectoral Nerve Block, Local Anesthesia
- Where
- Brazil
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Postoperative Pain, Surgery
Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control
To determine if Exparel (Liposomal Bupivacaine, an FDA approved drug) use in ultrasound guided Transversus Abdominis Plane (TAP) blocks may reduce opioid requirement use postoperatively, reduce pain scores postoperatively, reduce…
- Conditions
- Postoperative Pain, Surgery, Anesthesia, Local
- Trial name
- NCT03878888
- Testing
- Exparel 266 MG Per 20 ML Injection
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Analgesia, Acute Pain
Comparison of the Effects of TFPB and Anterior QLB on Postoperative Analgesia in Cesarean Section Surgery
This study evaluates the postoperative analgesic effects of transversalis fascia plane block and anterior quadratus lumborum block in patients having cesarean section under general anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT05408403
- Testing
- Regional anesthesia TFPB, Regional anesthesia QLB
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Ondokuz Mayıs University
Tonsillectomy, Ropivacaine
Analgesic Efficacy of Peritonsillar Ropivacaine Infiltration After Tonsillectomy in Children
Tonsillectomy is one of the most frequently performed surgical procedures in children and is commonly associated with significant postoperative pain.
- Conditions
- Tonsillectomy, Ropivacaine, Analgesia, Local Anesthesia
- Trial name
- NCT07825922
- Testing
- Peritonsillar infiltration with ropivacaine, Peritonsillar infiltration with normal saline, Normal Saline
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital, Mahdia
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Breast Cancer Female
USG PECS vs LIA for Breast Cancer Surgery
Breast cancer is the most common cancer for which women in the UK (United Kingdom) undergo surgery. A novel ultrasound guided regional anaesthetic technique called the 'Pecs 2' block has recently been described.
- Trial name
- NCT03555227
- Testing
- USG PECS2 with Drug A (active), Wound infiltration with Drug A (active)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- National Health Service, United Kingdom
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Chronic Subdural Hematoma
Propofol Target-Controlled Infusion Versus Dexmedetomidine for Sedation During Chronic Subdural Hematoma Surgery Under Local Anesthesia
Chronic subdural hematoma is a collection of old blood on the surface of the brain that mainly affects older adults. It is often treated by draining the blood through a small hole in the skull (burr hole), under local anesthesia…
- Trial name
- NCT07912203
- Testing
- Dexmedetomidine, Propofol (Astra-Zeneca)
- Volunteers
- 60 people
- Sponsor
- National Institute of Neurology, Tunisia
Anesthesia
Gaze Training on Task Performance Regional Anaesthesia
Regional anaesthesia is the performance of spinal, epidural or peripheral nerve blocks to allow patients to undergo surgery awake and to provide post-operative pain relief.
- Trial name
- NCT04426227
- Testing
- Gaze training, Discovery learning
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Patient With Bronchial Endoscopy
Contribution of Hypnotic Analgesia to Local Anesthesia During Bronchial Endoscopy.
Bronchial endoscopy (or bronchial fibroscopy) is an invasive diagnostic examination performed extremely frequently in the Pneumology department of the Dijon University Hospital, with an average of 1200 procedures per year.
- Trial name
- HypnoFibro (NCT03703960)
- Testing
- hypnotic analgesia, music
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Femoroacetabular Impingement
Regional Anesthesia in Hip Arthroscopy
The purpose of this research is to determine differences in outcomes in patients who receive regional anesthesia (a fascia iliaca block) versus placebo prior to undergoing hip arthroscopy with labral repair and/or debridement and…
- Trial name
- NCT02674113
- Testing
- regional anesthesia bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Hyperhidrosis, Axillary Hyperhidrosis
miraDry Post Market Tumescent Anesthesia Study
This clinical trial will collect data on the safety and efficacy of the miraDry treatment when High Volume Anesthesia (Tumescent Anesthesia) is used as an alternate method of anesthetizing the axilla prior to the miraDry System…
- Trial name
- NCT05546710
- Testing
- miraDry treatment
- Volunteers
- healthy volunteers welcome
- Sponsor
- miraDry, Inc.
Head and Neck Cancer
Regional Anaesthesia and Substance P in Head and Neck Cancer
In the clinical trial the investigators will observe the impact of regional anesthesia in addition to a general anesthesia on the expression of substance P in patients with unilateral Head or Neck cancer undergoing unilateral…
- Trial name
- SPRANC (NCT03081897)
- Testing
- SPRANC Block group, SPRANC Control group
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Regional Anesthesia, Anesthesia, Local
Analgesia in Minimally Invasive Direct Coronary Artery Bypass Grafting: Programmed Intermittent Bolus Infusions of Erector Spinae Plane Block Versus Paravertebral Block
Paravertebral block (PVB) has been regarded as effective regimen for pain control after cardiac surgery. As a novel analgesia technique, erector spinae plane block (ESPB) has been reported to provide effective analgesia after…
- Conditions
- Regional Anesthesia, Anesthesia, Local, Surgery
- Trial name
- NCT05320718
- Testing
- Ropivacaine
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University Third Hospital
Breast Cancer
Regional Anesthesia for Breast Surgery
Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block.
- Trial name
- NCT03941223
- Testing
- PECSII and paravertebral blocks
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Pain, Postoperative
The Effect of Local Anesthesia on Postoperative Pain in Vaginal Hysterectomy
The investigators aim is to study the effect of pre-operative local anesthetic on post vaginal hysterectomy pain.
- Trial name
- NCT03268525
- Testing
- Marcaine 0.5 % Injectable Solution, Sodium Chloride 0.9%
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Anesthesia, Local, Office Hysteroscopy
Intrauterine Anesthesia in Operative, Awake, Office Hysteroscopy. A Randomized Double-blind Placebo-controlled Trial
Objective: to evaluate intrauterine lidocaine infusion effectiveness in reducing pain associated with operative, awake office hysteroscopy Methods: A total of 100 patients will be randomized for this study The control group…
- Trial name
- NCT05610371
- Testing
- Lidocaine, Saline
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assuta Ashdod Hospital
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