Clinical trials: Locoregional Anaesthesia
Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications
Perineal Local Infiltration Study
The prevalence of birth canal lacerations is more than 70% of all deliveries in Canada. The repair of such lacerations is usually done using a pre-existing epidural analgesia.
- Conditions
- Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications, Anesthesia, Local
- Trial name
- PLIS (NCT03672500)
- Testing
- Bupivacaine 0.5%+Epinephrine 50mc
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Flutter, Atrial, Over 18 Years Old
Hypnosis in Interventional Electrophysiology
Hypnosis has already shown to decrease pain and anxiety in different surgical specialities. Nevertheless, its input has never been studied in cardiology.
- Trial name
- PAINLESS (NCT03250871)
- Testing
- Hypnosis
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Poitiers University Hospital
Elective Circumcision Surgery
A Comparison of the Efficacy of Sacral Erector Spinae Plane Block and Penile Block in Circumcision Surgery
Effective perioperative analgesia is crucial for reducing hospital stay in pediatric surgical patients. Opioid-based analgesia, although effective, may lead to respiratory depression in the postoperative period.
- Trial name
- SACRAL ESP (NCT07097844)
- Testing
- 0.8 mL/kg of 0.25% bupivacaine
- Volunteers
- 62 people
- Sponsor
- Siirt Training and Research Hospital
Intraoperative Nausea-retching-vomiting Episodes, Nausea Scores Will be Evaluated on the Verbal Analog Scale (VAS)
Antibiotic Prophylaxis and Nausea and Vomiting in Cesarean Section Under Regional Anesthesia.
The incidence of intraoperative nausea and vomiting in patients who undergo caesarean section (C/S) under regional anesthesia is approximately 30-80%.
- Trial name
- NCT04697277
- Testing
- Antibiotic prophylaxis timing (before skin incision and after cord clamping) for caesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Baskent University Ankara Hospital
Prostate Cancer
Feasibility of Virtual Reality Assistance in Prostate Biopsy Under Local Anesthesia.
The goal of this clinical trial is to test the impact of Virtual Reality (VR) assistance for anxiety management of patients undergoing prostate biopsies in local anaesthesia.
- Trial name
- NCT06274684
- Testing
- Use of Virtual Reality Assistance during prostate biopsies
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Head-Down Tilt Following Spinal Anesthesia
Cephalic Spread of Block With Head Down Tilt in Spinal Anaesthesia - A Randomised Controlled Study
Subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgeries. Several factors determine the spread of local anaesthetic solutions in CSF.
- Trial name
- NCT03491319
- Testing
- Group X - head low tilt, Group Y - head low tilt, Group C - neutral
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nitte University
Flexor Tendon Injury
Wide-Awake Local Anesthesia For Flexor Tendon Repair
Primary repair for flexor tendon lacerations remain the standard of care. However, despite recent advances in knowledge of tendon healing, suture material, and post-operative protocols, outcomes have been reported as fair or poor…
- Trial name
- NCT03752957
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Regional Anesthesia Morbidity, Cholecystitis, Chronic
Erector Spinae Plane Block as a Rescue Pain Therapy in Patients Undergoing Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy, one of the most commonly performed abdominal surgeries, is a gold standard therapy for surgical treatment of benign biliary diseases.
- Trial name
- NCT05706233
- Testing
- Erector Spina Plane Group, IV analgesic intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Istanbul Saglik Bilimleri University
Local Anesthesia
Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal
Double-blind, randomized, placebo-controlled trial to assess the efficacy of Lambdalina (lidocaine cream) in reducing pain associated with laser hair removal in women.
- Trial name
- NCT01360749
- Testing
- Lambdalina® (Lidocaine 4% cream)
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ISDIN
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Postoperative Pain, Analgesia
Comparison of Erector Spina Plan Block and Rhomboid Intercostal Block in Breast Surgery
In this study, the investigators compared ultrasound-guided erector spinae plane (ESP) block and rhomboid intercostal block (RIB) on postoperative analgesic effect in unilateral breast surgery.
- Trial name
- NCT06177665
- Testing
- Erector Spinae Plane Block, Rhomboid Intercostal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Kocaeli University
Suprainguinal Fascia Iliaca Block, Varicose Veins
Regional Anesthesia and Recovery After Varicose Vein RFA
This prospective observational study aims to compare the effects of spinal anesthesia and supra-inguinal fascia iliac block (SIFIB) on the quality of postoperative recovery in endovenous radiofrequency ablation (RFA) of varicose…
- Conditions
- Suprainguinal Fascia Iliaca Block, Varicose Veins, Radiofrequency Ablation, Regional Anaesthesia
- Trial name
- NCT07514000
- Testing
- Spinal anesthesia (heavy bupivacaine), SUPRAINGUINAL FACIA ILIACA BLOCK
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zonguldak Bulent Ecevit University
Intravenous Anesthetic Agent Overdose, Hand Injury Wrist
A Comparative Study Between Arm Intravenous Regional Anesthesia Versus Forearm Intravenous Regional Anesthesia in Patients Undergoing Hand and Wrist Surgery
The technique of intravenous regional analgesia using a tourniquet consisting of two cuffs over the upper arm is a well-known procedure, With the tourniquet being conventionally placed over the upper arm, a relatively high dose…
- Trial name
- NCT06448845
- Testing
- Arm intravenous regional anesthesia, Forearm IVRA block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Radial Artery Injury
Effect of Local Anesthesia Position of Lidocaine Injection on the Success Rate of Radial Artery Puncture Tube
Objective: To investigate the effect of lidocaine injection location on the success rate of ultrasound-guided radial artery catheterization in a single-center, randomized, controlled clinical trial.
- Trial name
- NCT06424145
- Testing
- Superior radial artery, Right side of radial artery
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ting Xu
Infection
PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy
Approximately one million transrectal prostate biopsies are performed annually in the U.S., and the risk of post- biopsy infection is increasing due to greater antibiotic resistance of rectal flora.
- Trial name
- PREVENT (NCT04843566)
- Testing
- Transperineal MRI-guided prostate biopsy, Transrectal MRI-guided prostate biopsy, Antibiotic (prophylaxis)
- Where
- 10 sites in United States
- Volunteers
- 687 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Neck Pain
Local Anesthetics in Cervical Epidural Injection
This study aims to evaluate the efficacy of local anesthetic drugs in cervical epidural injections for chronic neck pain.
- Trial name
- NCT07263672
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mustafa Kurçaloğlu
Postoperative Pain
QL Block Versus EO Plane Block for Analgesia After Open Nephrectomy
This prospective randomized clinical trial aims to compare two ultrasound-guided regional anesthesia techniques, the transmuscular quadratus lumborum (QL) block and the external oblique (EO) plane block, for pain relief after…
- Trial name
- NCT07787221
- Testing
- Quadratus Lumborum Block (QLB), External Oblique Plane Block
- Where
- 2 sites in Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Video-assisted Thoracoscopic Surgery, Paravertebral Block
TPVB or SPSIPB in Pain Management After VATS
The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic…
- Conditions
- Video-assisted Thoracoscopic Surgery, Paravertebral Block, Serratus Posterior Superior Intercostal Plane Block, Regional Anesthesia Morbidity
- Trial name
- NCT06426706
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Koç University
Benign Prostatic Hyperplasia
UroLift System TOlerability and ReCovery When Administering Local Anesthesia
The purpose of the study is to evaluate procedure tolerability and surgical recovery following the UroLift® system procedure when conducted with local anesthesia in subjects with symptomatic benign hyperplasia (BPH).
- Trial name
- LOCAL (NCT01876706)
- Testing
- UroLift® System
- Where
- 7 sites in United States
- Volunteers
- 51 people
- Sponsor
- NeoTract, Inc.
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