Clinical trials: Locoregional Anaesthesia
Cognitive Impairment, Frail Older Adults
Cognitive Fraility and Biomarkers in Older Patients
this study aimed to investigate the association between cognitive fraility and selected plasma and cerebrospinal fluid biomarkers related to neurodegenetaion and neuroinflammation in older adult patients undergoing elective…
- Conditions
- Cognitive Impairment, Frail Older Adults, Orthopaedic Surgery
- Trial name
- NCT07184073
- Testing
- assessment Mini mental state examination, assessment FRAIL scale, collecting cerebrospinal fluid during regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Baskent University
Nerve Block, Herniorrhaphy
IINB vs. QLB for Elective Open Inguinal Herniorrhaphy
Open inguinal herniorrhaphy is a common outpatient surgical procedure. Post-operative pain can be a significant hindrance to discharge from the post anesthesia care unit.
- Conditions
- Nerve Block, Herniorrhaphy, Regional Anesthesia
- Trial name
- NCT03007966
- Testing
- Ilioinguinal / Iliohypogastric Block, Quadratus Lumborum Block, Bupivacaine 0.25%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Arrythmia
Assessment of Adverse Cardiac Events Using Local Anesthesia With Adrenaline
The use of vasopressor supplement materials to local anesthetics is commonly used in procedures in various fields of dentistry, ENT (ear, nose, and throat), Plastic Surgery, Hand surgery and gastroenterology.
- Trial name
- NCT02738567
- Testing
- patients undergoing surgery or medical procedure
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Anesthesia, Local, Nerve Pain
SEQ Block for Perioperative Analgesia in Acetabular Surgery
The study will evaluate ultrasound guided SEQ block: single puncture combined lumbar erector spinae plane block and paraspinous sagittal shift (PSSS) quadratus lumborum block when compared with conventional intravenous morphine…
- Conditions
- Anesthesia, Local, Nerve Pain, Pain, Postoperative, Acetabular Fracture
- Trial name
- NCT04688814
- Testing
- Single puncture combined lumbar erector spinae plane block and quadrates lumborum block, Morphine Sulfate
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Alexandria University
COVID-19-Induced Parosmia
Stellate Ganglion Block for COVID-induced Parosmia
Chronic olfactory dysfunction, both hyposmia and parosmia, from the COVID-19 pandemic is a growing public health crisis with up to 1.2 million people in the United States affected.
- Trial name
- SGB (NCT06253806)
- Testing
- Stellate Ganglion Block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain, Anesthesia, Local
Continuous TQL Block for Elective Cesarean Section
The aim of this study is to investigate whether it is possible to prolong time to first opioid with the TQL block by inserting catheters bilaterally, providing continuous analgesia, in patients undergoing elective CS.
- Trial name
- NCT03663478
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Zealand University Hospital
Hernia, Inguinal
Spinal Versus Local Anesthesia for Hernia Repair
patients underwent inguinal hernia repair; Group A patients received Subarachnoid anesthesia; Group B Patients underwent surgery with local anesthesia (Mepivacaine 2%) performed by the surgeon; Pain assessment was performed using…
- Trial name
- SPINOFAST (NCT05136534)
- Testing
- spinal anesthesia, local anesthesia
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Campus Bio-Medico University
Primary Total Knee Arthroplasty
Quadriblock Versus "IPACK + Femoral Triangle Block + Obturator Nerve Block" in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- QuITO (NCT04499716)
- Testing
- IPACK, Femoral triangle block, Obturator nerve block
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Clinique Medipole Garonne
Hip Fractures, Surgery
SiFi vs FNB Local Anesthesia for Hip Fracture Surgeries
The goal of this clinical trial is to compare two commonly used local/regional anesthesia techniques in adults patients undergoing hip fracture surgery.
- Conditions
- Hip Fractures, Surgery, Anesthesia, Local
- Trial name
- NCT06296758
- Testing
- Regional anesthesia
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of Alberta
Postoperative Pain
COMPARISON OF INTRAOPERATIVE LOCAL ANESTHETIC APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS
Since 1987, laparoscopic cholecystectomy has become the standard procedure for gallbladder stones and lesions. Complications due to improvements in laparoscopy and increased surgical experience have decreased day by day, but…
- Trial name
- NCT03790007
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Inguinal Hernia
Local Anesthetic Infiltration VS Trasversalis Fascia Block VS Spinal Anesthesia
Propose to comparison effectiveness of blind local anesthetic infiltration with ultrasound guided Transversals Fascia Block and Spinal Anesthesia in patients undergoing to inguinal hernia repair surgery.
- Trial name
- NCT03128216
- Testing
- Blind Local Anesthetic infiltration, Transversals Fascia Block, Spinal Anesthesia
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Istituti Ospitalieri di Cremona
Anesthesia, Local, Shoulder Surgery
The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two local anaesthetics..
- Trial name
- NCT00801138
- Testing
- saline, Dexamethasone, ropivacaine
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- The Cleveland Clinic
Anesthesia, Local
Split Face Study of the Duration of Local Anesthetics - Fourth Arm
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT06694714
- Testing
- 0.5 ml lidocaine + epinephrine 1:100,000, 1.0 ml lidocaine + epinephrine 1:100,000
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Arthropathy of Knee, Anesthesia
IPACK Nerve Block for Total Knee Arthroplasty
Double-blind, randomized controlled clinical trial to test the efficacy of IPACK on postoperative opioid consumption, patient satisfaction, pain scores, mobility, and several other secondary outcomes in adults undergoing primary…
- Trial name
- NCT03921034
- Testing
- Ropivacaine, Saline
- Volunteers
- 72 people
- Sponsor
- Ochsner Health System
Pain
Comparison of Two Different Methods of Delivering Local Analgesia During Intra-articular Corticosteroid Injections in Children With Juvenile Idiopathic Arthritis
Chronic arthritis (inflammation of joints) in children is known as Juvenile Idiopathic Arthritis (JIA). Often, to control the swelling and to help reduce the pain in the joint, medications (steroids) are injected into the joint.
- Trial name
- NCT00465504
- Testing
- iontophoresis
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Hip Fracture, Analgesia Post Fracture
PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture
Pericapsular Nerve Group Block (PENG) is an effective regional anaesthesia modality in providing analgesia following neck of femur fracture.
- Trial name
- NCT07046052
- Testing
- continuous infusion of levobupivacaine, Programmed Intermittent Bolus of Levobupivacaine
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- University College Cork
Regional Anesthesia
Visualizing Peripheral Nerves Using Ultrasound-Guided Approach
Peripheral nerve blocks of the limbs are very useful in providing anesthesia and pain relief for orthopedic procedures in the limbs (elbows, arms, knees, and legs).
- Trial name
- NCT00221949
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Catheterization, Peripheral
The Main Content of This Study is to Use Virtual Reality Technology Combined With Local Anesthesia With Lidocaine Injection at Different Times to Reduce the Pain of PICC in School-age Children
We try to through the use of virtual reality technology in combination with lidocaine in different injection time to reduce the pain of PICC catheter school-age children.
- Trial name
- NCT06562829
- Testing
- Virtual reality technology, different timing of lidocaine injection
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Qi Yu
Cardiovascular Surgery, Regional Anaesthesia
Fascial Plane Blocks In Cardiac Surgery
The aim of the present study is to evaluate the effects of the recto-intercostal fascial plane block (RIFPB) or the rectus sheath block (RSB) combined with the pectoral-intercostal fascial plane block (PIFPB) on postoperative…
- Conditions
- Cardiovascular Surgery, Regional Anaesthesia, Postoperative Analgesia
- Trial name
- NCT07622823
- Testing
- PIFPB + RIFPB, PIFPB + RSB, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Antalya Health Sciences University
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