Clinical trials: Locoregional Anaesthesia
Anesthesia
Evaluation of Regional Blocks Efficacy in Orthognathic Surgery
The proposed study, which will be carried out on 72 male and female patients, who have reached bone maturity, are younger than 50 years and underwent orthognathic surgical procedures.
- Trial name
- NCT07133048
- Testing
- Levobupivakain 0.25 %, NaCl 0.9 %
- Where
- Croatia
- Volunteers
- 72 people
- Sponsor
- Clinical Hospital Center Rijeka
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT05447455
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Fracture Fixation, Internal, Metacarpal Fracture
The Effect of Forearm Nerve Blocks on Pain-free Tourniquet Time Compared to Local Anesthetic for Awake Hand Surgery
Wide-awake surgery with local anesthesia is a widely described approach to performing numerous minor hand procedures, such as tendon repairs and percutaneous fracture pinning, but is less frequently used for longer procedures…
- Conditions
- Fracture Fixation, Internal, Metacarpal Fracture, Finger Fracture, Anesthesia, Local
- Trial name
- NCT04787835
- Testing
- Forearm nerve block, Local anesthetic infiltration
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Lacerations, Wound Repair
Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults
This prospective comparative study evaluates pain experience in adult patients undergoing laceration repair in the emergency department using either topical lidocaine-adrenaline-tetracaine (LAT) gel or lidocaine infiltration as…
- Conditions
- Lacerations, Wound Repair, Acute Traumatic Wounds, Pain Management
- Trial name
- NCT07480135
- Testing
- Lidocaine-Adrenaline-Tetracaine (LAT) Gel, Lidocaine infiltration
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Vrije Universiteit Brussel
Arthroplasty, Replacement, Knee
Testing Regional Anesthesia Techniques for Up and Early Discharge Following Knee Arthroplasty - A Feasibility Study
To assess feasibility of a a trial investigation postoperative patient-reported quality of recovery after total knee arthroplasty (TKA) with periarticular joint injection (PAI) ± single shot adductor canal block with or without…
- Trial name
- TRUE KnORTH 2 (NCT06054750)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Sponsor
- McMaster University
Analgesic Adverse Reaction
Psoas Compartment Block (PCB) Versus L.A Infiltration and Remifentanil Infusion During EVAR
Endovascular aneurysm repair (EVAR) was introduced in 1990 for the first time as a minimally invasive procedure instead of the conventional open surgical repair, with the aim to decrease morbidity and mortality .
- Trial name
- NCT03443518
- Testing
- Psoas Compartment Block (PCB), Local Anesthesia infiltration, Normal saline 0.9% IV infusion
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Dr. Erfan and Bagedo General Hospital
Anesthesia
Low Fresh Gas Flow in Prone Position
Low flow anesthesia in the prone position was safe in terms of systemic hemodynamics and did not reduce cerebral oxygenation compared to normal flow.
- Trial name
- NCT05462327
- Testing
- Low Fresh Gas Flow in Prone Position, Normal Fresh Gas Flow in Prone Position
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Abdominal Muscles/Ultrasonography, Adult
Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair
Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage
- Trial name
- NCT01589796
- Testing
- TAP block
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stamford Anesthesiology Services, PC
Knee Replacement, Total, Pain, Postoperative
Two Different Blocks for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty
The frequency of femoral nerve block and adductor canal block for analgesia after TKA(total knee arthroplasty) increases with the use of ultrasonography in regional anesthesia.
- Conditions
- Knee Replacement, Total, Pain, Postoperative, Anesthesia, Regional
- Trial name
- NCT04286035
- Testing
- Bupivacaine Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Anesthesia, Local
Changes in Tissue Oxygenation Following Regional Anesthesia
Adequate tissue oxygenation is required for effective white blood cell function and bactericidal activity. Decreased tissue oxygenation is a risk factor for perioperative wound infections.
- Trial name
- NCT01418690
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Nationwide Children's Hospital
Primigravida in Labour Pains
Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia
The purpose of this study is to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia.
- Trial name
- NCT01205360
- Testing
- Bupivacaine-Fentanyl Mixture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Ropivacaine, Laparoscopic Cholecystectomy
Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain
Pain still remains a limiting factor in early discharge of patients undergoing laparoscopic cholecystectomy. Almost all earlier studies done to compare the efficacy of local anaesthetics used intraperitoneally as compared to…
- Conditions
- Ropivacaine, Laparoscopic Cholecystectomy, Pain
- Trial name
- NCT03265223
- Testing
- 0.2% ropivacaine
- Volunteers
- 353 people
- Sponsor
- Jawaharlal Nehru Medical College
Video Assisted Thoracoscopy, Anesthesia
Double Regional Anesthesia in Video Assisted Thoracoscopy
Monocentric, randomized, controlled, single-blind study who's aim is to demonstrate the efficacy of the association of paravertebral block and serratus plane block with paravertebral block alone
- Trial name
- DRAVATS (NCT03852862)
- Testing
- Serratus plane block and paravertebral block, paravertebral block
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Rouen
Keratoplasty, Regional Block
Comparative Study Between Dexamethasone Versus Magnesium Sulfate in Medial Episcleral Technique in Keratopalsty Surgeries
The aim of this work is to compare between the effects of addition of Dexamethasone versus magnesium sulfate to local anesthetic mixture in medial episcleral technique in keratoplasty operations
- Trial name
- NCT07847489
- Testing
- Bupivacaine hydrochloride, Dexamethasone, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post Operative Pain, Regional Anesthesia Morbidity
Does ESP Block Reduce Pain and Opiates Consumption After Surgery
The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72…
- Conditions
- Post Operative Pain, Regional Anesthesia Morbidity, Opioid-Related Disorders, Chronic Pain
- Trial name
- NCT05512897
- Testing
- erector spinea plane block
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michael Dubilet MD
Analgesia, Acute Pain
Comparison of the Effects of TFPB and Anterior QLB on Postoperative Analgesia in Cesarean Section Surgery
This study evaluates the postoperative analgesic effects of transversalis fascia plane block and anterior quadratus lumborum block in patients having cesarean section under general anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT05408403
- Testing
- Regional anesthesia TFPB, Regional anesthesia QLB
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Ondokuz Mayıs University
Anesthesia, Abdominoplasty
Efficacy of Postoperative Epidural Anesthesia Following Abdominoplasty
Effective postoperative pain management is essential for patient satisfaction and therefore intraoperative regional nerve blocks have become more and more popular in abdominoplasties.
- Trial name
- EDA (NCT05822882)
- Testing
- Epidural anesthesia
- Where
- Germany
- Volunteers
- 112 people
- Sponsor
- Klinik Bogenhausen
Post-spinal Hypotension, Orthopedic Surgery
Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries…
- Conditions
- Post-spinal Hypotension, Orthopedic Surgery, Spinal Aneshtesia
- Trial name
- NCT06995690
- Testing
- Ketamine, Normal Saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Carotid Thrombendarterectomy, Cerebral Oxygenation
Cerebral Oximetry for Carotid EEA
Aim oft he study is to compare two different devices for cerebral oximetry (FORE-SIGHTTM Monitor (CAS Medical Systems, Branford, Connecticut, USA and INVOSTM Somanetics, Troy, Michigan, USA) in patients undergoing surgical…
- Conditions
- Carotid Thrombendarterectomy, Cerebral Oxygenation, NIRS, Regional Anesthesia
- Trial name
- NCT02203370
- Testing
- NIRS - Near-infrared spectroscopy
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Salzburger Landeskliniken
Therapy Animals, Dental Anxiety
Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?
The goal of this clinical trial is to assess whether the presence of a certified therapy dog during dental procedures that require an injection reduces anxiety and improves behavior in pediatric dental patients.
- Conditions
- Therapy Animals, Dental Anxiety, Child Behavior, Anesthesia, Local
- Trial name
- NCT06057090
- Testing
- Therapy Dog
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
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