Clinical trials: Locoregional Anaesthesia
Lidocaine
Effect of Different Concentrations of Lidocaine in Relieving Pain in Wide Awake Hand Surgery Using Tumescence
Lidocaine has been used along with adrenaline in tumescent anesthesia for a variety of procedures. This has been quite popular especially in wide awake surgery of the hand with no tourniquet.
- Trial name
- NCT04692896
- Testing
- lidocaine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- King Edward Medical University
Hip Arthropathy, Hip Arthrosis
Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery
Pain after total hip replacement (THR) surgery is severe. The target population is elderly and comorbid. Level III analgesics are responsible for significant side effects in this population.
- Trial name
- PENGORINF (NCT06257160)
- Testing
- Surgical infiltration, PENG Block ultrasound-guided
- Where
- France
- Volunteers
- 224 people
- Sponsor
- CHU de Reims
Anesthesia, Local
Peribulbar Block: Lidocaine-bupivacaine vs Lidocaine-bupivacaine-fentanyl
Ophthalmological procedures such as cataract extraction can be carried out with a peribulbar block (PBB). The advantages of this anesthetic technique include a lower incidence of coughing, unwanted movements and emesis during…
- Trial name
- NCT03713762
- Testing
- peribulbar block 1 lidocaine/bupivacaine, peribulbar block 2 lidocaine/bupivacaine/fentanyl
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centro Medico Docente la Trinidad
Pain After Shoulder Surgery
Does a Low Volume Ultrasound-Guided Technique Reduce Common Complications of Interscalene Brachial Plexus Block?
Peripheral nerve blocks provide many advantages for patients (excellent pain control and reduction in nausea) undergoing upper and lower limb surgery however several commonly occurring complications can produce annoying but…
- Trial name
- NCT00497354
- Testing
- Variation in volume of local anesthetic, Ultrasound-guided interscalene brachial plexus block
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hip Dislocation, Congenital, Postoperative Pain
Quadratus Lumborum Block for Pediatric Hip Surgery
Caudal blockade (CB) is one of the most frequently performed regional anaesthetic techniques in children. It's an efficient way to offer perioperative analgesia for painful sub-umbilical interventions but with high incidence of…
- Conditions
- Hip Dislocation, Congenital, Postoperative Pain, Anesthesia
- Trial name
- NCT04292782
- Testing
- anterior Quadratus lumborum block, caudal block
- Where
- Tunisia
- Volunteers
- 40 people
- Sponsor
- University Tunis El Manar
Abscess
Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage
Cutaneous abscesses (boils) are collections of pus or infection in the skin, and are a frequent reason for emergency department visits.
- Trial name
- NCT01673061
- Testing
- Lidocaine, Vapocoolant
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Albert Einstein Healthcare Network
Arthroscopic Shoulder Surgery
Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block
Interscalene brachial plexus block (ISBPB) is a common nerve block given to patients who are undergoing shoulder surgery. This block has a low, but still significant, rate of complications.
- Trial name
- NCT00731146
- Testing
- Ultrasound Minimum Effective Anesthetic Volume, Nerve Stimulator Minimum Effective Anesthetic Volume
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Spinal Anesthesia
Chloroprocaine for Inguinal Herniorrhaphy
This study is to determine the minimum effective dose for intrathecal chloroprocaine in inguinal herniorrhaphy in outpatients using a Combined Spinal Epidural (CSE) anesthesia.
- Trial name
- NCT03805503
- Testing
- Chloroprocaine 1% Injectable Solution
- Volunteers
- 12 people
- Sponsor
- University Hospital, Ghent
Anesthesia, Local
Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block Approaches
This randomized, double-blinded volunteer study compares two ways of performing the adductor canal (AC) nerve block at the mid-thigh to see which approach more reliably numbs the anteromedial knee.
- Trial name
- NCT07444827
- Testing
- Traditional adductor canal block, NVM (nerve to vastus medialis) targeted adductor canal block, Chloroprocaine Injection
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block
Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery
Interscalene block is still the gold standard in shoulder surgery analgesia. The most important side effect is diaphragm paralysis due to the phrenic nerve being affected.
- Conditions
- Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block, Analgesia, Arthroscopic Shoulder Surgery
- Trial name
- NCT04626869
- Testing
- Evaluation of Diaphragm Movement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alper Tunga Dogan
Regional Anesthesia
Ultrasound-guided Peripheral Nerve Blocks - a Database
Peripheral nerve blocks are often used in anaesthesia. They can be used as the only method of anaesthesia during surgery or in combination with other methods, e.g., general anaesthesia and sedation.
- Trial name
- Blockbase (NCT06460792)
- Testing
- Ultrasound-guided peripheral nerve block
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- Nordsjaellands Hospital
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Postamputation Pain, Lower Limb Amputation
Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury
Acute post-amputation pain remains a significant clinical challenge in patients with combat-related lower limb injuries and may negatively affect early rehabilitation, mobility, and opioid consumption.
- Conditions
- Postamputation Pain, Lower Limb Amputation, Combat Trauma
- Trial name
- APAPMACRLLI (NCT07863921)
- Testing
- Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia
- Where
- Ukraine
- Volunteers
- 36 people
- Sponsor
- Kharkiv National Medical University
Dental Implants, Local Anesthesia
Comparison of Anesthetic Efficacy and Safety Between Nerve Block and Infiltrative Technique for Mandibular Posterior Implant Placement.
The goal of this triple blind randomized clinical trial is to compare the safety, efficacy and postoperative pain between the inferior dental nerve block (IDNB) and the infiltrative technique (TINF) in the placement of mandibular…
- Trial name
- NCT06641232
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for mandibular posterior implant placement.
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Mastectomy; Lymphedema, Chronic Pain
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy.
- Conditions
- Mastectomy; Lymphedema, Chronic Pain, Regional Anesthesia Morbidity, Opioid Use
- Trial name
- NCT07561411
- Testing
- Paravertebral block, Erector Spinae block
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Intensive Care Unit
Regional Anaesthesia in Intensive Care Unit
Pain is a major problem in Intensive Care Unit (ICU). Adequate pain management not only means decreasing the pain intensity, but also improving the functionality and allowing the early mobilization that is a prerequisite for…
- Trial name
- Week'ALR (NCT05131633)
- Where
- 19 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Learning Curve, Suprainguinal Fasya Iliaca Block
Learning Curve of Ultrasound-Guided Suprainguinal Fascia Iliaca Block: A Prospective Observational Study
Competence in ultrasound-guided regional anesthesia (UGRA) requires practitioners to acquire cognitive and technical skills. Various difficulties have been identified in anesthesia residents' learning UGRA skills.
- Conditions
- Learning Curve, Suprainguinal Fasya Iliaca Block, Ultrasound-guided Regional Anesthesia (UGRA)
- Trial name
- NCT06708598
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Senay Canikli
Anesthesia
Virtual Reality Hypnosis Distraction Utility to Improve Tolerance to Regional Anaesthesia
Regional anaesthesia has many advantages but it might be a stressful and painful experience. Usually, the anesthetist administers a pharmacologic intravenous sedation to achieve patient's comfort.
- Trial name
- NCT04024904
- Testing
- OncomfortTM device
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Erasme University Hospital
Regional Anesthesia, Computed Tomography
Radiological Study of PENG Block Depth
This study evaluates the depth of anatomical landmarks required in regional anaesthesia to perform either Femoral Nerve Block or PENG Block.
- Conditions
- Regional Anesthesia, Computed Tomography, Anatomical Description
- Trial name
- Tomo-PENG (NCT04337164)
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Peribulbar Anesthesia
Dexmedetomidine Adjuvant in Retinal Surgery
During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl .
- Trial name
- NCT02282787
- Testing
- DEXMEDETOMIDINE
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- King Saud University
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