Clinical trials: Locoregional Anaesthesia
Pain, Postoperative
Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study
The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound…
- Trial name
- NCT00508092
- Testing
- local anesthetic administration
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Royal Berkshire NHS Foundation Trust
Pain, Postoperative, Pain, Acute
External Oblique Intercostal Block in Laparoscopic Cholecystectomy
Adequate postoperative pain management is essential for improving patient comfort and recovery after laparoscopic cholecystectomy.
- Conditions
- Pain, Postoperative, Pain, Acute, Opioid Use
- Trial name
- NCT07164664
- Testing
- External Oblique Intercostal Block, Port-Site Infiltration, ıv morphine PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Equally of Delivery Systems of Local Anesthesia in Bronchoscopy
Topical Anesthesia / Bronchoscopy
The primary aim of this study is to compare a simplified single-use product (LMA® MAD Nasal™ Intranasal Mucosal Atomization Device, Teleflex medical, Kernen Germany) for topical nasopharyngeal anesthesia in comparison to a…
- Trial name
- TNA (NCT02237651)
- Testing
- topical anesthesia multi-use device, topical anesthesia Intranasal Mucosal Atomization
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- Hannover Medical School
Neoplasm of Lung, Thoracic Surgery, Video-Assisted
Postoperative Analgesia With a Catheter Under the Erector Spinae Muscle for Videothoracoscopic Lung Surgery
The purpose of the research is to prove the analgesic efficacy of a novel technique in regional anaesthesia, i.e. the catheter under the erector spinae muscle (ESC).
- Trial name
- ESCAV (NCT04665531)
- Testing
- Erector Spinae Catheter, Intercostal block, Ropivacaine 0.2% Injectable Solution
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- Surgery Bitenc
Adjuvants, Anesthesia
Neostigmine Versus Dexamethasone as Adjuvants to Lidocaine During Intravenous Local Anesthesia
Intravenous regional anesthesia (IVRA) is described firstly in 1908 by August Bier. It is simple, safe, reliable, less cost, efficient method in forearm surgery.
- Trial name
- NCT03021772
- Testing
- Neostigmine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Colon Carcinima
The Application of the ELFI-TECH Monitor for Perioperative Hemodynamic Measurements
The elfitor device is a small non invasive device that uses dynamic light scattering to measure skin bloodflow, blood velocity, coagulation and hemodynamic parameters.
- Trial name
- NCT02628431
- Testing
- Elfi tech monitor
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Early Confirmation of Epidural Catheterization
Early Detection of Epidural Onset by Temperature Change
Traditionally, placement of the epidural catheter is based on hand feel of passing through the ligamentum flavum as well as "loss of resistance" while injecting the air through the needle.
- Trial name
- NCT02838056
- Testing
- epidural injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University WanFang Hospital
Regional Anesthesia Morbidity, Postoperative Pain
Retrolaminar Thoracic Paravertebral Block
This clinical study will be conducted on female patients admitted to The General Surgery Department of Tanta Faculty of Medicine for a period of 9 months.
- Trial name
- NCT04162951
- Testing
- Ordinary approach paravertebral block, Retrolaminar paravertebral block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
End Stage Renal Disease
Local Anaesthesia vs Regional Block for Arteriovenous Fistulae
End stage renal failure (ESRF)describes an irreversible loss in renal function. The majority of these patients will opt for haemodialysis (HD)as their chosen method of renal replacement therapy (RRT).
- Trial name
- NCT01706354
- Testing
- Local Anaesthetic, Regional anaesthetic
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- Emma Aitken
Local Anesthesia of the Skin
Fractional Laser Assisted Delivery of Anesthetics III
The purpose of this study is to compare the effect of pretreatment with two different ablative laser modalities, a CO2 laser and an Er:YAG laser, and to assess the role of laser density in fractional laser assisted topical…
- Trial name
- NCT02938286
- Testing
- Fractional CO2 laser, 2.5 mJ, 5% density, Fractional CO2 laser, 2.5 mJ, 15% density, Fractional Er:YAG laser, 9 mJ, 5% density
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
Anesthesia, Analgesia
Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT05191966
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Knee Osteoarthritis, Postoperative Pain Management
Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty
This prospective, randomized, double-blind clinical trial aims to compare the effects of two different posterior knee analgesia techniques-iPACK block (Interspace Between the Popliteal Artery and the Capsule of the posterior…
- Conditions
- Knee Osteoarthritis, Postoperative Pain Management, Total Knee Arthroplasty
- Trial name
- BiFeS-TKA (NCT07248072)
- Testing
- Adductor Canal Block (ACB) Only, IPACK block, BiFeS Block
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ataturk University
Quality of Recovery (QoR-15), Sphenopalatine Ganglion Block
Effect of Bilateral SPG and Infraorbital Nerve Blocks on Recovery After Septorhinoplasty
This prospective, randomized, double-blind controlled study aims to compare the effects of bilateral sphenopalatine ganglion and infraorbital nerve blocks on postoperative recovery quality in patients undergoing elective…
- Conditions
- Quality of Recovery (QoR-15), Sphenopalatine Ganglion Block, Infraorbital Nerve Block
- Trial name
- NCT06929429
- Testing
- Bilateral Sphenopalatine Ganglion Block, Bilateral Infraorbital Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Konya City Hospital
Anesthesia, Local
A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population
A Phase 3, randomized, active-controlled, study in pediatric subjects. It is designed to evaluate the safety and anesthetic efficacy of one dose of AG-920 ophthalmic solution compared to Proparacaine Hydrochloride Ophthalmic…
- Trial name
- NCT05325853
- Testing
- AG-920, Proparacaine Ophthalmic
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Carpal Tunnel Syndrome
Pain in Carpal Tunnel Release Wide-awake Local Anesthesia With no Tourniquet vs Local Anesthesia With Tourniquet
The aim of this study is to compare pain, satisfaction, and experience between patients who underwent Carpal Tunnel Release with wide-awake local anesthesia no tourniquet technique and local anesthesia with a tourniquet.
- Trial name
- NCT05747846
- Testing
- Carpal tunnel release, WALANT technique, Carpal tunnel release using a tourniquet
- Where
- Argentina
- Volunteers
- 82 people
- Sponsor
- Hospital Italiano de Buenos Aires
Dental Anxiety, Anesthesia, Local
Dental Anaesthesia Affects Pain Level
Background: Needles are the most feared tools, making anaesthetic injection a worrying practice. Aim: To compare intraosseous (IOA) and needle-free dental anaesthesia (NFA) methods that painless anaesthesia.
- Trial name
- NCT05002673
- Testing
- DENTAL LOCAL ANESTHESİA
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pain, Postoperative, Opioid Use
ESP Block Versus Wound Infiltration for Laminectomy
Spinal surgery is often burdened by perioperative pain and its treatment presently represents a challenge for anesthetists. An inadequate intra and postoperative analgesic therapy leads to a delay in the mobilization of the…
- Conditions
- Pain, Postoperative, Opioid Use, Anesthesia, Local, Surgery
- Trial name
- NCT05271331
- Testing
- ESP block with saline, Wound infiltration with saline, ESP block with local anesthetic
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- University of Padova
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Spinal Anesthesia Evaluation, Cesarean Delivery
Preoperative Data and the Spinal Spread of Local Anesthetic in Cesarean Section
This study is designed to assess possible relation between the anthropometric data of pregnant women at term, as well as their babies, and the maximal level of sensory blockade following spinal anesthesia for cesarean section.
- Trial name
- NCT07197398
- Testing
- Spinal block level analysis, Data collection, Sub-group analysis
- Where
- Poland
- Volunteers
- 183 people
- Sponsor
- Centre of Postgraduate Medical Education
Arterio-venous Fistula
The Use of NIRS in Brachial Plexus Block
The study is planed on ASA I-III, 18-80 years old 60 patients developing chronic renal failure and needing arteriovenous fistula surgery for dialysis program in Istanbul Medeniyet University Goztepe Research Hospital.
- Trial name
- NCT04177901
- Testing
- Near infrared spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
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