Clinical trials: Long Term Antibiotics
Urinary Tract Infections
Reducing Antibiotic Prescriptions for Urinary Tract Infection in Long-Term Care Facilities
This cluster randomized controlled study evaluates the effect of a tailored observation, reflection and communication tool on used by long-term care facility staff on antibiotic prescription for urinary tract infection in…
- Trial name
- NCT03715062
- Testing
- Dialogue tool
- Where
- Denmark
- Volunteers
- 1,491 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Prosthetic Joint Infection (PJI)
A Phase 2b Study to Evaluate the Efficacy, Safety, and PK Profiles of TNP-2092 Administered Via IA Injection in PJI Participants
This is a Phase 2b, randomized, controlled, open-label clinical study evaluating the efficacy, safety, and local PK profiles of TNP-2092 administered via IA injection on a background of antibiotic treatment in participants with…
- Trial name
- NCT07858916
- Testing
- TNP-2092 for injection, Vancomycin Hydrochloride for Injection, Oral antibiotics
- Where
- China
- Volunteers
- 40 people
- Sponsor
- TenNor Therapeutics (Zhongshan) Limited
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Long Term Antibiotic Therapy on Exacerbation Rate in Stable COPD Patients
This study investigates if long term use of the antibiotic doxycycline can reduce exacerbations in COPD patients. Half of the patients will receive doxycycline which the other half will receive a placebo.
- Trial name
- NCT02305940
- Testing
- Doxycycline
- Where
- 3 sites in United Kingdom
- Volunteers
- 222 people
- Sponsor
- Imperial College London
Multi-antibiotic Resistance
Pathway From Functional Disability to Antimicrobial Resistance in Nursing Home Residents
Multidrug-resistant organisms (MDROs) are endemic in nursing homes (NHs) with prevalence rates surpassing those in hospitals. The aim of the study is to design and evaluate the effectiveness of a multi-component intervention to…
- Trial name
- NCT02909946
- Testing
- Multi-modal Infection Control Program
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- University of Michigan
Clostridioides Difficile Infection
Long-Term Outcomes After CDI: FMT Versus Antibiotic-Only Treatment
The goal of this observational study is to learn about the long-term effects of fecal microbiota transplantation (FMT) compared with antibiotic-only treatment in adults who were treated for Clostridioides difficile infection…
- Trial name
- LTO-CDI (NCT07569380)
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Umeå University
Antibiotic Initiation, Antibiotic Duration
Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care
There is a high rate of inappropriate antibiotic use in long-term care (LTC) facilities, with both unnecessary initiation and prolongation of treatments.
- Trial name
- FIRST AID-LTC (NCT03807466)
- Testing
- Dynamic/Interactive vs. Static/Paginated Report, LTC Physicians Enrolled vs. Not Enrolled in Reports
- Where
- Canada
- Volunteers
- 356 people
- Sponsor
- Institute for Clinical Evaluative Sciences
Chronic Obstructive Pulmonary Disease (COPD).
Development of an Optimal Antibiotic Regime for Long-term Therapy in Stable Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) is the cause of considerable deaths, and exacerbations (flare up of symptoms) are a major cause of hospital admission in the UK.
- Trial name
- NCT01398072
- Testing
- Moxifloxacin, Azithromycin, Doxycycline
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University College, London
Urinary Tract Infection, Antibiotic Use
Optimizing Antibiotic Use in Long Term Care
The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic…
- Trial name
- NCT00243360
- Testing
- diagnostic and treatment clinical algorithms
- Where
- Canada
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Catheter-related Bloodstream Infection (CRBSI) Nos
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
The purpose of the investigation is to compare two catheter lock solutions (TaurolockTMHep100 and Heparin 100 IE/ml), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a central…
- Trial name
- NCT01948245
- Testing
- TaurolockTMHep100, Heparin 100 IE/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Palle Bekker Jeppesen
Long Term Antibiotics, Chemotherapy
FX vs. ECG Guidance for PICC Insertion
The aim of this study is to compare two techniques of placing a peripherally inserted central venous catheter (PICC). The first technique, uses ECG based electromagnetic guidance (ECG-EM).
- Conditions
- Long Term Antibiotics, Chemotherapy, Total Parenteral Nutrition
- Trial name
- NCT03652727
- Testing
- ECG-EM Guidance, FX Guidance
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Salah D. Qanadli
Respiratory Tract Infections
Long Term Effect of General Practitioner Education on Antibiotic Prescribing
Respiratory tract infections are the most common indication for antibiotic prescribing in primary care. Several studies have shown a strong relationship between antibiotic use and bacterial resistance.
- Trial name
- PAAIR2 (NCT01107223)
- Testing
- Experimental: Training to antibiotic prescription, No education on antibiotic prescription rules.
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Henri Mondor University Hospital
Obesity
Short- and Long-Term Effects of Antibiotics on Childhood Growth
The objectives of the proposed study are to assess the effects of different types, timing, and amount of antibiotic use in the first two years of life with (Specific Aim 1) body mass index (BMI) and obesity at ages 5 and 10 years…
- Trial name
- ABX (NCT02744846)
- Testing
- Antibiotics exposure
- Volunteers
- 681,739 people
- Sponsor
- Harvard Pilgrim Health Care