Clinical trials: Long-Haul COVID-19
Long Covid-19
LOng COvid COmorbidities: Andrological, Reproductive, Sexual Dysfunctions in Patients Recovered From COVID-19
Considering the compelling amount of studies focused on patients in the active phase of COVID-19 disease and the scarcity of studies focused on patient cured from disease aimed at evaluating the sequelae of Severe Acute…
- Trial name
- NCT05379556
- Testing
- Assessment of andrological profile of LO-COCO-ANDRO male patients, Assessment of reproductive function of LO-COCO-ANDRO male patients, Assessment of sexual function of LO-COCO-ANDRO male patients
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Long COVID, Long COVID Syndrome
Immunoadsorption in Autoimmune Long COVID
Some people continue to have serious symptoms long after COVID-19, such as extreme fatigue and feeling worse after activity. In some patients, this may happen because the immune system is attacking the body by mistake.
- Conditions
- Long COVID, Long COVID Syndrome, Long COVID-19 Syndrome, Post COVID Syndrome
- Trial name
- TURNLongCOVID (NCT07316127)
- Testing
- Immunoadsorption
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle
Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Long COVID or Postacute sequelae of COVID-19 infection (PASC) are increasingly recognised complications, defined by lingering symptoms, not present prior to the infection, typically persisting for more than 4 weeks.
- Conditions
- COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle, Remodeling, Vascular, Left Ventricular Dysfunction
- Trial name
- MYOFLAME-19 (NCT05619653)
- Testing
- Prednisolone, Losartan
- Where
- 5 sites in Austria, Germany
- Volunteers
- 279 people
- Sponsor
- Valentina Puentmann
COVID-19, COVID-19 Respiratory Infection
Low-field Magnetic Resonance Imaging in Pediatric Post Covid-19
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a new coronavirus and identified causative agent of COVID-19 disease.
- Conditions
- COVID-19, COVID-19 Respiratory Infection, Long COVID
- Trial name
- FASCINATE (NCT05445531)
- Testing
- Low-field magnetic resonance imaging, Nailfold capillaroscopy, Spiroergometry
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
COVID-19
Disability Following Hospitalization in People of Working-age Surviving SARS-CoV-2 Infection - COVID-19
The purpose of the study is to describe disability following hospitalization in people of working-age surviving COVID-19.
- Trial name
- DisCOVID (NCT04724395)
- Testing
- Hospitalization
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-Acute COVID-19 Syndrome
Role of OMT in the Management of the Persistent Post-COVID-19 Symptoms
The goal of this observational study is to determine the feasibility of conducting a large-scale study on the effect of using osteopathic manipulative treatment (OMT) to treat patients with post-COVID-19 symptoms.
- Trial name
- ROMPS (NCT06016543)
- Testing
- osteopathic manipulative treatment (OMT)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- A.T. Still University of Health Sciences
Post COVID-19 Condition, Post-COVID-19 Syndrome
Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments
Over 500 million people have been infected with COVID-19, and to date, more than 6 million people have died. Many individuals who have recovered from COVID-19 continue to experience symptoms even after they have been "cured" of…
- Conditions
- Post COVID-19 Condition, Post-COVID-19 Syndrome, Post-COVID Syndrome, COVID-19
- Trial name
- PCS-HBOT (NCT06082518)
- Testing
- Monoplace Hyperbaric Chamber (Class III medical device).
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Fatigue, Cognitive Deficit
Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients
The study explore the efficacy of PEA-LUT in patients suffering from neurological symptoms of Long-Covid
- Conditions
- Fatigue, Cognitive Deficit, COVID-19, Neurophysiologic Abnormality
- Trial name
- PL-PC19 (NCT05311852)
- Testing
- palmitoylethanolamide co-ultramicronized with antioxidant flavonoid luteolin (PEA-LUT)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Department of Neurorehabilitation, Hospital of Vipiteno-Sterzing (BZ) Italy
COVID Long-Haul, COVID-19
Neural and Cognitive Consequences of COVID-19 Survival
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021).
- Conditions
- COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog
- Trial name
- NCT06208943
- Testing
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Post-Viral Fatigue Syndrome
Low-dose Naltrexone for Post-COVID Fatigue Syndrome
This study aims to determine if low-dose naltrexone (LDN) reduces fatigue, improves related symptoms, and reduces inflammatory markers in peripheral blood in cases with Post-COVID-19 Fatigue Syndrome (PCFS) from COVID-19 (i.e.
- Trial name
- NCT05430152
- Testing
- Low-Dose Naltrexone
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Luis Nacul
PASC Post Acute Sequelae of COVID 19, Long COVID
From Inflammation to Remodelling Towards Personalized Diagnosis in Post-acute Sequelae of COVID-19
Rationale: The diagnosis and pathogenesis of long COVID remains unknown. We have previously shown that [68Ga]FAPI Positron Emission Tomography-Computed Tomography (PET/CT) imaging shows potential for diagnosis and molecular…
- Conditions
- PASC Post Acute Sequelae of COVID 19, Long COVID, Long Covid-19, PASC
- Trial name
- LIBERATE (NCT06911476)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Long COVID, Long Covid19
Understanding the Long-term Impact of COVID-19 in Adults
Long COVID (LC) affects an estimated 5-10% of individuals with SARS-CoV-2 causing a persistent physical, cognitive, and functional impairment with potentially severe socioeconomic consequences.
- Trial name
- NCT07498504
- Where
- United States
- Volunteers
- 5,205 people
- Sponsor
- NYU Langone Health
Post-Acute COVID19 Syndrome, COVID-19
FMT for Post-acute COVID-19 Syndrome
In recovered COVID-19 patients, emerging global data have reported the presence of long COVID, that is, at least one symptom that an alternative diagnosis cannot explain has been persistent for four or more weeks after the…
- Trial name
- FMT-PACS (NCT05556733)
- Testing
- Faecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Stroke, Multiple Sclerosis
Design and Validation of Innovative Strategies Based on Dual-Task Approach
People affected by Stroke, Multiple Sclerosis (MS), and Parkinson's disease (PD) share severe and complex disabilities. Widespread neuro-inflammatory processes represent an important pathogenetic component in all three…
- Conditions
- Stroke, Multiple Sclerosis, Parkinson Disease, Dual Task Exercises
- Trial name
- START (NCT07254377)
- Testing
- Dual Task exercise, Physical therapy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Post COVID Syndrome Long Covid, Post COVID Syndrome
Whole-Body Electrostimulation for Functional Recovery in Post-COVID Syndrome
Post-COVID syndrome is a condition that affects some people after recovering from the acute phase of COVID-19. Common symptoms include persistent fatigue, reduced physical capacity, and difficulties performing everyday…
- Conditions
- Post COVID Syndrome Long Covid, Post COVID Syndrome, Long COVID Fatigue, Long Covid
- Trial name
- WB-EMS PostCOV (NCT07312357)
- Testing
- Whole-Body Electromyostimulation Suit
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Post-acute Sequelae of SARS-CoV-2 Infection
Cognitive-Sensorimotor Function in Long-COVID
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance.
- Trial name
- NCT06850350
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
COVID-19 Respiratory Infection
Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
The objective of this project is to assess the effects of a 2-month cardiopulmonary rehabilitation program on cardiorespiratory fitness in long COVID19 patients.
- Trial name
- COVID-Rehab (NCT05035628)
- Testing
- Cardiopulmonary exercise training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louis Bherer
Long COVID, Post Acute Sequelae of COVID-19
Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Therapy for the Treatment of Post COVID Condition
The RECLAIM study platform will be used to explore whether the use of Hyperbaric Oxygen therapy (HBOT) improves the symptoms of post covid cognitive dysfunction. Hyperbaric oxygen therapy is a well-established medical treatment.
- Conditions
- Long COVID, Post Acute Sequelae of COVID-19, Post-COVID-19 Condition
- Trial name
- RECLAIM-HBOT (NCT06452095)
- Testing
- Hyperbaric Oxygen therapy
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Long Covid19
Non-pharmacological and TCM-based Treatment for Long COVID Symptoms
Cognitive impairment is one of the commonly reported Long COVID symptoms, mainly in terms of memory, attention, and executive function.
- Trial name
- NCT06042777
- Testing
- Acupuncture and TCM-based lifestyle management
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Long COVID
Sauna for Long Covid
Research suggests that Whole Body Hyperthermia in a sauna-like environment can reduce symptoms related to post-acute sequelae of SARS-CoV-2 (PASC), or Long Covid.
- Trial name
- NCT05931497
- Testing
- whole body hyperthermia
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Massachusetts General Hospital