Clinical trials: Long-Haul COVID-19
Long COVID
Effect of Lithium Therapy on Long COVID Symptoms
This study will assess low-dose lithium's effects on several different symptoms experienced by long COVID patients.
- Trial name
- NCT05618587
- Testing
- Lithium
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- State University of New York at Buffalo
Covid19
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells to Treat Post COVID-19 "Long Haul" Pulmonary Compromise
This is a Phase 2a randomized, placebo-controlled study designed to investigate the efficacy, safety and tolerability of COVI-MSC in treating post COVID-19 "long haul" pulmonary compromise.
- Trial name
- BR (NCT04992247)
- Testing
- COVI-MSC
- Sponsor
- Sorrento Therapeutics, Inc.
Chronic Cough, Long COVID
Etiology Analysis of Chronic Cough After COVID-19 Infection and Research on the Efficacy of ICS or ICS/LABA
In this real-world study, we retrospectively classified the causes of chronic cough in patients, analyzed the prevalence of cough-variant asthma, and prospectively evaluated and compared the improvement of cough symptoms and…
- Trial name
- NCT06503939
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Xiangya Hospital of Central South University
COVID-19
Effect of Virtual Reality in Patients With Long Covid-19
SARS-CoV-2 was first detected in Wuhan, Hubei Province, China, in late 2019. It is a highly contagious virus that has been reported to occur in humans and is said to cause pneumonia.
- Trial name
- NCT06374446
- Testing
- Classical Treatment, Virtual Reality Combined with Classical Treatment, Virtual Reality
- Volunteers
- 56 people
- Sponsor
- Istinye University
Post-Acute COVID-19, Post COVID-19 Condition
Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection
Prospective cohort study to evaluate the utility of quantitative CT analysis to assess ventilation and perfusion defects in patients with Post-acute Sequelae of SARS-CoV-2 (PASC) and functional limitations
- Conditions
- Post-Acute COVID-19, Post COVID-19 Condition, Post Viral Fatigue, Dyspnea
- Trial name
- PASC VQ (NCT05866952)
- Testing
- Computed Tomography of the Chest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Chronic Fatigue Syndrome, COVID-19, Long Haul
Investigation of Treating Chronic Fatigue Syndrome After COVID With Pharmacotherapy (Pregabalin) or Complex Rehabilitation
This is a single-center, prospective, randomized, double-blind (pharmacotherapy), placebo-controlled, and comprehensive rehabilitation phase II clinical trial to determine the usefulness of pregabalin in a new indication…
- Trial name
- POSTCOVID (NCT05967052)
- Testing
- Pregabalin, Independent walking training, Gradual movement therapy in the ward
- Where
- Poland
- Volunteers
- 23 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Long Covid19, Pulmonary Rehabilitation
Combined Pulmonary Rehabilitation and PMR for Long-Term COVID-19 Symptoms: A RCT
Our study aimed to evaluate the effectiveness of a 21-day program combining pulmonary rehabilitation (PR) with progressive muscle relaxation (PMR) in patients experiencing long-term symptoms of COVID-19.
- Conditions
- Long Covid19, Pulmonary Rehabilitation, Progressive Muscle Relaxation
- Trial name
- NCT06492577
- Testing
- Pulmonary rehabilitation protocol, Progressive muscle relaxation protocol
- Where
- Romania
- Volunteers
- 61 people
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara
Post COVID-19 Condition (PCC)
Basel Long COVID-19 Cohort Study and Digital Long COVID Substudy
The Basel Long COVID Cohort Study (BALCoS) is a registry-based cohort study that focuses on the patients' present health status, symptoms, the course of these symptoms, and potential mechanisms involved.
- Trial name
- BALCoS/DiLCoS (NCT05781893)
- Testing
- Digital intervention (DiLCoS), Data collection
- Where
- Switzerland
- Volunteers
- 196 people
- Sponsor
- University Hospital, Basel, Switzerland
Covid19, Sequelae of; Infection
Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
The study will assess whether Niagen, a safe dietary supplement, improves recovery of COVID-19 related symptoms in individuals who were infected at least 2 months prior to study entry ("Long-COVID" "Long-haulers").
- Conditions
- Covid19, Sequelae of; Infection, Cognitive Symptom
- Trial name
- NCT04809974
- Testing
- Niagen
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Long Covid, Covid19
Clinical and Haematological Phenotypes in Long COVID
Analysis of the relationship between clinical characteristics and haematological parameters in long COVID. The novel coronavirus (Covid19) pandemic declared by the World Health Organisation in March 2020 has had an enormous huge…
- Trial name
- NCT04659889
- Testing
- Blood sampling (venesection)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- HCA International Limited
COVID-19
Exploring Gas Transfer and the Utility of Dynamic Chest Radiography in Long Covid Patients
This study aims to identify if breathless patients with Long COVID have reduced transfer factor on pulmonary function testing and if the degree of transfer factor reduction is correlated with the symptom severity and…
- Trial name
- LoCTDC (NCT05862896)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Post-COVID-19 Syndrome
Feasibility of a Well-being Promotion Self-management Intervention in Post-COVID-19 Patients
A training comprised of positive psychological interventions set out to improve mental well-being was developed for post-COVID-19 patients. This study aims to evaluate the feasibility and acceptability of this training.
- Trial name
- NCT06658340
- Testing
- Positivity in Post-COVID
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- University of Twente
Long COVID, Long Covid19
Symptom Tracking in Long COVID Patients Using Formula C™ Sublingual Drops
This is a digital symptom tracking study of Formula C™, a full cannabis flower formulation, rich in cannabinoids and terpenes, that has been shown to improve symptoms in people with Long COVID.
- Conditions
- Long COVID, Long Covid19, Post-Acute COVID-19, Post-Acute COVID-19 Syndrome
- Trial name
- NCT06163690
- Testing
- Endourage Targeted Wellness Formula C™, a full hemp flower extract
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endourage, LLC
Long COVID, COVID-19
Five-year Follow-up After Sars-CoV-2 Infection: Prevalence and Evolution of Post-acute Sequalae of COVID-19 (PASC)
This multicenter, observational, retrospective-prospective study aims to evaluate the prevalence and trajectory of Post-Acute Sequelae of COVID-19 (PASC) approximately 5 years after SARS-CoV-2 infection.
- Conditions
- Long COVID, COVID-19, Post-Acute COVID-19 Syndrome, Post-Acute COVID-19 Infection
- Trial name
- PASC-5Y (NCT07766512)
- Testing
- Post-Acute Sequelae of COVID-19 (PASC) Assessment
- Volunteers
- 900 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Long COVID
Biosound Therapy as a Treatment for Long COVID Patients
This study aimed to explore the impact of the Biosound Therapy Systerm on long COVID symptoms while determining feasibility of a future full-scale Randomized Controlled Trial.
- Trial name
- NCT05848401
- Testing
- Biosound Therapy System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Anxiety Relief Center
Long Covid19, Dietary Supplements
IMMUNERECOV CONTRIBUTES TO IMPROVEMENT OF RESPIRATORY AND IMMUNOLOGICAL RESPONSE IN POST-COVID-19 PATIENTS.
Background: COVID-19 left consequences in different organs from months to years requiring different types of rehabilitation. In fact, a severe loss in the lung function, and in the respiratory and peripheral muscle strength is…
- Conditions
- Long Covid19, Dietary Supplements, Respiratory Tract Infections, Inflammation
- Trial name
- IRPC (NCT06166030)
- Testing
- Nutritional blend (ImmuneRecov).
- Where
- 2 sites in Brazil
- Volunteers
- 58 people
- Sponsor
- Federal University of São Paulo
Long COVID Syndrome
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?
Millions have developed Long COVID (LC), and recent findings show an association between taurine deficiency (an amino acid) and symptoms in LC.
- Trial name
- NCT07312409
- Testing
- Taurine supplementation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- York University
Long COVID, Long Covid19
Stellate Ganglion Block to Treat Long COVID 19 Case Series
An assessment of the effectiveness of Stellate Ganglion Block in alleviating symptoms of Long COVID-19.
- Conditions
- Long COVID, Long Covid19, Post-COVID-19 Syndrome, Post Acute COVID-19 Syndrome
- Trial name
- NCT05812209
- Testing
- Stellate Ganglion Block
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Metamorphosis LTD
Cardiovascular Diseases, Long Covid19
High-definition Transcranial Direct Current Stimulation and Chlorella Pyrenoidosa to Reduce Cardiovascular Risk
Recent investigations have shown that of the patients who were affected by SARCov2 have remained with persistent symptoms in a high proportion.
- Trial name
- HD-TDCS (NCT06255600)
- Testing
- High Definition-transcranial Direct Current Stimulation, Chlorella Pyrenoidosa
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Tinnitus
DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury
The goal of this clinical trial is to test a compounded dimethyl sulfoxide (DMSO)-based dual-route therapy for adults with refractory subjective tinnitus linked to long-COVID (post-acute sequelae of SARS-CoV-2) or post-COVID-19…
- Trial name
- DART-TINN (NCT07567274)
- Testing
- DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Leading Edge Clinic