Clinical trials: Long-Term Memory
Chronic Phase Stroke Patients
Exploring the Long-term Effects of Cognitive Exercise on Cognition After Stroke
This project will investigate the effectiveness of an intensive and focused working memory training program for chronic stroke patients.
- Trial name
- NCT01948089
- Testing
- Variable Structured Cognitive Exercise, Constant Structured Cognitive Exercise
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Nova Scotia Health Authority
HIV Infection
Observation of HIV-Infected Children Receiving Protease Inhibitor and Reverse Transcriptase Inhibitor
This study will continue to follow children who participated in an earlier National Cancer Institute trial of HIV treatment with a protease inhibitor.
- Trial name
- NCT00001826
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Mild Cognitive Impairment, Memory Impairment
Diminishing Accelerated Long-term Forgetting in Mild Cognitive Impairment
This study is designed as a prospective, double-blind, placebo-controlled, randomized parallel-group study that will be completed at the clinical research facility at St. James' Hospital and at Trinity College Dublin, Ireland.
- Conditions
- Mild Cognitive Impairment, Memory Impairment, Memory Disorders in Old Age
- Trial name
- NCT05289804
- Testing
- NITESGON, Lidocaine / Prilocaine Topical Cream, C5/C6 stimulation
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- University of Dublin, Trinity College
Mild Cognitive Impairment (MCI), Amnestic Mild Cognitive Impairment - aMCI
Auditory Stimulation During Sleep to Enhance Long-Term Memory in Amnestic MCI
This study aims to evaluate the efficacy and safety of Elevvo AudiStim, a sleep auditory stimulation device, as a symptomatic treatment for patients with amnestic mild cognitive impairment (aMCI).
- Conditions
- Mild Cognitive Impairment (MCI), Amnestic Mild Cognitive Impairment - aMCI, Alzheimer or Mild Cognitive Impairment
- Trial name
- NCT07402590
- Testing
- Auditory Stimulation
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Bitbrain
Neurocognitive Disorders, Dementia
Major Memory 2: A Long-term Group Cognitive Stimulation Program
This study aims to evaluate the effect of a long-term group cognitive stimulation (CS) program on the cognitive function of institutionalized elderly people with neurocognitive disorders.
- Conditions
- Neurocognitive Disorders, Dementia, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT04178564
- Testing
- Cognitive Stimulation
- Where
- 8 sites in Portugal
- Volunteers
- 70 people
- Sponsor
- Rsocialform - Geriatria, Lda
Cognitive Development
Fatty Acid Levels and Memory in Breastfed Children
Purpose: To explore the relation between breastmilk nutrients and the cognitive abilities of breastfed infants. Phase 1: Near 3 months of age child and mother saliva samples for DNA obtained with breast milk sample.
- Trial name
- NCT01942434
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
COVID-19, Neuro-Degenerative Disease
Randomised Clinical Trial to Evaluate the Efficacy of an Online Cognitive Rehabilitation Programme (COPERIA-COG) for Patients With Persistent COVID-19
The pandemic caused by SARS-CoV-2 infection has led to the emergence of diffuse and heterogeneous persistent symptoms in addition to the well-known acute symptoms, which have come to be referred to as persistent COVID.
- Conditions
- COVID-19, Neuro-Degenerative Disease, Psychological, SARS CoV 2 Infection
- Trial name
- COPERIA-COG (NCT05629897)
- Testing
- Sessions of cognitive stimulation
- Where
- 2 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Pain, Traumatic Memory
Traumatic Long-term Memory of Pain in Humans
Few studies have focused on understanding the mechanisms underlying pain memory in humans. Thus, this project aims to investigate the link between pain memorisation and memorisation of the associated context by addressing the…
- Trial name
- TRAUMADOL (NCT04189965)
- Testing
- Validation of virtual environment and auditive stimulation with virtual reality glasses (Pilot phase), Electrical cutaneous stimulation and auditive stimulation (Principal Experimental phase), Electrical cutaneous stimulation and auditive stimulation (Secondary Experimental phase)
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Impaired Cognition, Geriatric Disorder
The Efficacy of Using Volunteers to Implement a Cognitive Stimulation Program in Two Long-Term Care Homes
Many volunteers visiting seniors make socially-based "friendly visits". This study investigated the efficacy of volunteers making visits focused on stimulating cognition.
- Conditions
- Impaired Cognition, Geriatric Disorder, Learning Disorders, Age-Related Memory Disorders
- Trial name
- VolCogStim (NCT01818778)
- Testing
- Cognitive stimulation program, Standard Friendly Visit
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cerebrovascular Disorders, Memory
Roflumilast to Treat Cognitive Sequela After Stroke
The aim of the current project is to validate the effects of chronic rolflumilast treatment (12 weeks) on cognitive functions (i.e.
- Conditions
- Cerebrovascular Disorders, Memory, Functional Recovery, Drug Intervention
- Trial name
- ROSTMEMA (NCT04854811)
- Testing
- Roflumilast Oral Tablet
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University
Alzheimer's Disease
A Study of Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease
The purpose of this study is to compare the effectiveness and safety of 2 years of treatment with galantamine as compared with placebo of patients who have mild to moderately severe Alzheimer's disease (AD).
- Trial name
- NCT00679627
- Testing
- Galantamine
- Where
- 95 sites in Czechia, Estonia and 10 more
- Volunteers
- 2,051 people
- Sponsor
- Janssen Research & Development, LLC
Age-related Memory Disorders, Mood Disorders
Omega-3 and Blueberry Supplementation in Age-Related Cognitive Decline
The aim of this study is to determine the efficacy of 6 months' dietary supplementation with omega-3 fatty acids and whole freeze dried blueberry powder in improving cognition in older adults.
- Trial name
- NCT01746303
- Testing
- Omega-3 fatty acid, Blueberry powder
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Diabetes Mellitus, Type 2 Diabetes
Validation of Insulin Dose Prediction Model Based on Artificial Intelligence Algorithm
The present study aims to conduct a prospective controlled trial comparing an LSTM-based artificial intelligence (AI) prediction model and clinicians' experience in the efficacy and safety of blood glucose control in hospitalized…
- Trial name
- NCT07066891
- Testing
- CSII in the prediction model group, CSII in the empirical group
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Sun Yat-sen University
Dementia, Caregiver Burden
MIND: Care Coordination for Community-living Person With Dementia
This is a 24-month, prospective, single- blind, randomized controlled trial evaluating the MIND at Home-streamlined dementia care coordination intervention (called MIND-S) in a cohort of 300 community-living persons with dementia…
- Trial name
- MIND at Home (NCT02396082)
- Testing
- MIND-S Intervention, Augmented Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Infections, Streptococcal
Long-term Follow-up Study of Children Previously Primed With GSK Pneumococcal Vaccine (GSK1024850A) and of Unprimed Children
The objective of this study is to evaluate the immune memory through the administration of an additional dose of GSK Biologicals' pneumococcal conjugate vaccine GSK1024850A, the antibody persistence and long-term effect on…
- Trial name
- NCT00950833
- Testing
- Pneumococcal vaccine GSK1024850A
- Where
- 10 sites in Czechia
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Effects of cogniVida™ on Learning and Memory and in Comparison to Placebo After Long-term Supplementation
The purpose of the study is to examine the efficacy of cogniVida™ on learning and memory performance (executive function, associative, spatial and verbal memory) as well as on mood and attention parameters after four, eight and…
- Trial name
- MemIprov (NCT01647919)
- Testing
- cogniVida™ 100 mg/day
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Refractory Epilepsy
Acute and Long Term Effects of VNS on Memory in Patients With Refractory Epilepsy
Refractory epilepsy patients implanted with a vagus nerve stimulator perform a memory test at baseline in three conditions: invasive vagus nerve stimulation (VNS), transcutaneous vagus nerve stimulation (taVNS) and sham…
- Trial name
- NCT05031208
- Testing
- Memory task
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- University Hospital, Ghent
Brain Mapping, Language Disorder
Brain Areas Involved in Sound and Spoken Word Memory
Background: Studies have shown that animals such as monkeys and dogs have excellent sight and touch memory but perform poorly on sound memory tasks.
- Conditions
- Brain Mapping, Language Disorder, Adult, Healthy
- Trial name
- NCT01375595
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Children Born Extremely Premature, Disturbance of Visuo-spatial Working Memory
Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial
Prematurity tends to increase in France in recent years and more children born extremely premature infants survive. If severe impairments have stabilized, the majority of former extremely premature children have…
- Trial name
- EPIREMED (NCT02757794)
- Testing
- computerized cognitive remediation program, standard remediation
- Where
- 18 sites in France
- Volunteers
- 166 people
- Sponsor
- Assistance Publique Hopitaux De Marseille