Clinical trials: Long-term Care
Frailty, Sedentary Behavior
Stand if You Can: A Standing Intervention in Long Term Care
It is currently unknown if reducing sitting time, an activity that is highly prevalent in frail older adults living in long term care (LTC) facilities, is associated with an improvement in physical capacity such as walking speed.
- Conditions
- Frailty, Sedentary Behavior, Physical Disability
- Trial name
- NCT03796039
- Testing
- Standing
- Where
- Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Urinary Tract Infection
Cranberry for UTI Prevention in Residents of Long Term Care Facilities
Urinary tract infections (UTIs) affect over 7 million men and women per year and cost the health care industry over 1 billion dollars annually.
- Trial name
- PACS (NCT00596635)
- Testing
- Once Daily Cranberry Capsule, Twice Daily Cranberry Capsules
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Yale University
Glabellar Lines, Lateral Canthal Lines
Long-term Treatment of Moderate to Severe Glabellar Lines and Lateral Canthal Lines
This is a phase 3, multicenter, open-label study to evaluate the safety of QM1114-DP for the long term treatment of moderate to severe Glabellar (Frown) Lines (GL) and Lateral Canthal Lines (Crow's Feet and LCL).
- Trial name
- READY-4 (NCT04225260)
- Testing
- botulinum toxin neuromodulator
- Where
- 30 sites in United States, Puerto Rico
- Volunteers
- 902 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Incontinence-associated Dermatitis
Prevention of Incontinence-associated Dermatitis
Incontinence-associated dermatitis (IAD) is an inflammation of the skin caused by prolonged direct contact of the skin with urine and/or stool. Elderly and care-dependent people are often affected by this type of inflammation.
- Trial name
- PID (NCT05403762)
- Testing
- ESENTA™ Skin Barrier Spray (ConvaTec, UK), Hydrophobes Basisgel DAC
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Influenza
Randomized Trial of High Dose Influenza Vaccine in Long Term Care Setting
The purpose of the study is to compare the performance of two currently available influenza (flu) vaccines. This study will try and determine if the high dose flu vaccine provides protection that is the same or better than that…
- Trial name
- NCT01654224
- Testing
- High Dose Inactivated Influenza Vaccine, Standard Dose Inactivated Influenza Vaccine
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Novel Influenza A/H1N1
Surveillance for Adverse Events Following Pandemic H1N1 Immunization
Influenza vaccines are continuously modified to adjust to the virus antigenic shifts or drifts, and its safety profile may vary.
- Trial name
- NCT01289418
- Volunteers
- 6,525 people, healthy volunteers welcome
- Sponsor
- PHAC/CIHR Influenza Research Network
Obesity
Evaluating the Effectiveness of a Stepped-Care Approach to Long-Term Weight Loss (The Step-Up Study)
The number of overweight and obese adults in the United States is increasing at a rapid rate. A "stepped-care" weight loss program, which at key times increases the frequency of contact between an individual trying to lose weight…
- Trial name
- Step-Up (NCT00714168)
- Testing
- Standard Behavioral Weight Loss Program, Stepped-Care Weight Loss Program
- Where
- 2 sites in United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nicotine Dependence
Cessation Screening Project
This project will use the Multiphase Optimization Strategy (MOST) to guide the development of optimized treatment strategies for the two most effective smoking cessation medications (Combination Nicotine Replacement [C-NRT] and…
- Trial name
- NCT04188873
- Testing
- Preparation Varenicline and Standard Duration Varenicline, Preparation Varenicline and Extended Duration Varenicline, Standard Duration Varenicline
- Where
- 2 sites in United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
COVID-19
CONFIDENT: Supporting Long-term Care Workers During COVID-19
The CONFIDENT Study is an online three-arm randomized trial that aims to help long-term care workers in the United States feel more confident about the Coronavirus Disease 2019 (COVID-19) vaccines.
- Trial name
- NCT05168800
- Testing
- Dialogue-Based Webinar, Social Media Website, Enhanced Usual Practice
- Where
- United States
- Volunteers
- 2,634 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Xerosis Cutis
Skin Health and Effectiveness of Standardized Skin Care Regimens in Nursing Home Residents
Residents of institutional long-term care facilities are at high risk for developing skin and tissue diseases, e.g. xerosis cutis (including pruritus), infections (e.g., tinea pedis, candidiasis), chronic wounds or neoplastic…
- Trial name
- NCT02216526
- Testing
- Cetaphil® Restoraderm, Excipial
- Where
- Germany
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Dementia, Caregivers
VA Cultivating Access to Resources, Education, and Skills for Dementia Caregivers
The purpose of this study is to study the effects of an education and skill-building intervention on family caregivers of Veterans with dementia.
- Conditions
- Dementia, Caregivers, Neurodegenerative Diseases, Brain Diseases
- Trial name
- VACARES (NCT02106065)
- Testing
- Education and Skill-Building Rehabilitation (ESBR), Supplemental Education Materials
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alzheimer Disease, Dementia
Utilizing Senior Companions to Enhance Dementia Care
The inability of healthcare systems to effectively manage Alzheimer's disease and related dementias (ADRD) often results in families remaining unaware of important community-based, long-term services and supports (LTSS) that…
- Trial name
- NCT03667924
- Testing
- PorchLight Project
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stress and Burnout
Certified Nursing Assistants' Wellbeing
Certified nursing assistants (CNAs), who provide the majority of care to persons with chronic disease and/or cognitive impairment from Alzheimer's disease and related dementias, face tremendous job and home stress, and as a…
- Trial name
- CNA (NCT03720652)
- Testing
- 8-Week Mindful Self-Compassion (MSC), 6-Week Mindful Self-Compassion (MSC)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Long-Term Care, Long-term Care Facility
Effect of Empathy-Based Program on Nursing Assistants in Long-term Care Facilities
This randomized controlled trial aims to explore the impact of an Empathy-Based Program on the level of empathy among nursing assistants in a long-term care facility.
- Trial name
- NCT07044492
- Testing
- Virtual Reality (VR) with Debriefing
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Dementia, Depression
Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients
This study is designed to test the hypothesis that an intervention increasing exposure to daylight indoors will reduce depression and other neuropsychiatric symptoms among people living with dementia in long term care facilities.
- Conditions
- Dementia, Depression, Behavior Disorders
- Trial name
- NCT03483896
- Testing
- Daylight Intervention
- Where
- 8 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Respiratory Syncytial Virus (RSV)
Immunogenicity of RSV Vaccines in Residents of Long-Term Care Facilities (LTCF)
This clinical trial is studying the newly licensed RSV vaccines in adults over age 60 years living in long-term care facilities (nursing homes) by comparing the immune response to their vaccine to adults over age 60 years living…
- Trial name
- NCT06077149
- Testing
- RSV vaccine
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Stroke, Balance; Distorted
Explorations of the Benefits of the ZeroG TRiP System to Improve Balance in Patients Following Stroke
Strokes are neurological events that can lead to devastating physical and cognitive deficits, such as the inability to ambulate, impaired balance regulation, and loss of coordination.
- Trial name
- NCT04919161
- Testing
- Body weight support system control group, Body weight support system with balance perturbations
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Gaylord Hospital, Inc
Loneliness
Reducing Loneliness of Older Adults in Long Term Care Facilities Through Collaborative Augmented Realities
The goal of this clinical trial is to test the use of head-mounted display (HMD) augmented reality (AR) in older adults residing in communities or assisted care facilities.
- Trial name
- NCT06179225
- Testing
- HMD AR, 2-D AV
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University