Clinical trials: Loss of Consciousness
Loss of Consciousness
Remimazolam Bolus for General Anesthesia
It is important to estimate the adequate dose of remimazolam intravenous bolus injection to induce the loss of consciousness. We will determine the ED50 and ED95 of remimazolam intravenous bolus on the loss of consciousness in…
- Trial name
- NCT04901871
- Testing
- 0.02 mg/kg, age<65, 0.07 mg/kg, age<65, 0.12 mg/kg, age<65
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Gangnam Severance Hospital
Electroencephalogram, Consciousness, Loss of
The Electroencephalogram and Clinical Effect of Ketamine
The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain.
- Trial name
- NCT03679390
- Testing
- Ketamine
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- National Taiwan University Hospital
Traumatic Brain Injury With Prolonged Loss of Consciousness, Stroke
Evaluation of Consciousness by Brain-computer Interface in Severely Brain Damaged Patients
The objective of this study is to show that the measurement of auditory and vibro-tactile evoked potentials, or the recording of the EEG signal during a motor imaging task, can be used in routine clinical situations to explore…
- Conditions
- Traumatic Brain Injury With Prolonged Loss of Consciousness, Stroke, Brain Hypoxia
- Trial name
- AWAKE (NCT03998930)
- Testing
- Clinical evaluation of consciousness by the Coma Recovery Scale Revised (CRS-R)
- Where
- 4 sites in France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Arrhythmia, Hemorrhage
Suitability of Unobtrusive Bed Monitoring and Wrist-worn Heart Rate Monitor for Patient Monitoring
Novel technology enables it to monitor noninvasively the vital signs of a patient. Such a monitoring is immediately required to improve patient safety and to reduce hospital readmissions.
- Conditions
- Arrhythmia, Hemorrhage, Septic Shock, Consciousness, Loss of
- Trial name
- BedMon (NCT03572751)
- Testing
- Bed-, wrist- and ECG-sensor monitoring
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Tampere University Hospital
Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms
Purpose of this study is to investigate the mechanisms of action of hyperbaric oxygen therapy for persistent post-concussive symptoms after mild tramatic brain injury
- Trial name
- BIMA (NCT01611194)
- Testing
- Hyperbaric oxygen (HBO2) at 1.5 atms
- Where
- 5 sites in United States
- Volunteers
- 71 people
- Sponsor
- U.S. Army Medical Research and Development Command
Traumatic Brain Injury With Prolonged Loss of Consciousness
A Trial to Determine the Feasibility and Effectiveness of Early Multisensory Stimulation Intervention in Patients in the Trauma-Neurosurgical Intensive Care Unit (TNICU) Following Severe Acquired Brain Injury
St. Michael's Hospital (SMH) provides service to individuals with some of the most severe brain injuries and intensive care needs in Canada.
- Trial name
- NCT02589223
- Testing
- Multisensory Stimulation, Control
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Unity Health Toronto
Loss of Consciousness
Sufentanil Bispectral Index Elderly
We compared BIS values during propofol stepwise induction with or without concomitant sufentanil in patients ≥ 65 years .
- Trial name
- NCT02831101
- Testing
- Sufentanil
- Volunteers
- 71 people
- Sponsor
- University Hospital, Geneva
Traumatic Brain Injury With Brief Loss of Consciousness
Multidisciplinary Treatment in Patients With Mild Traumatic Brain Injury
The aim of the study is to compare a multidisciplinary examination and follow up by rehabilitation program with a multidisciplinary examination, good advice and follow up by the family doctor.
- Trial name
- NCT00869154
- Testing
- primary care follow up, Multidisciplinary follow up
- Where
- 2 sites in Norway
- Volunteers
- 151 people
- Sponsor
- Haukeland University Hospital
Loss of Consciousness
The Effects of Different Doses of Dexmedetomidine on Propofol Requirement for Loss of Consciousness Undergoing Bispectral Index: a Double-blinded, Placebo-controlled Trial
The purpose of this study is to evaluate the effects of different dexmedetomidine on the propofol requirement for loss of consciousness undergoing bispectral index.
- Trial name
- NCT02783846
- Testing
- normal saline, dexmedetomidine 0.5 µg/kg, dexmedetomidine 1.0 µg/kg
- Volunteers
- 73 people
- Sponsor
- General Hospital of Ningxia Medical University
Traumatic Brain Injury With Brief Loss of Consciousness
The Clinical Research on the Relationship Between Depression and Gut Microbiota in TBI Patients
Microbiome studies may be highlighted as crucial in the development of depression for TBI patients. The microbiota-gut-brain connection may further provide an opportunity for microbiota manipulation to treat the TBI patients with…
- Trial name
- NCT02874027
- Testing
- The TBI patients with depression
- Where
- China
- Volunteers
- 50 people
- Sponsor
- General Hospital of Ningxia Medical University
Motor Vehicle Accidents, TBI (Traumatic Brain Injury)
Concussion in Motor Vehicle Accidents: The Concussion Identification Index
The primary goal of this study is to provide clinicians with a brief, patient self-administer instrument yielding a single composite score that reliably correlates with objective findings on standardized neurocognitive assessment…
- Conditions
- Motor Vehicle Accidents, TBI (Traumatic Brain Injury), Brain Contusion, Brain Injuries
- Trial name
- CIDI (NCT02858544)
- Testing
- The Concussion Identification Index, ImPACT
- Where
- United States
- Volunteers
- 1,790 people
- Sponsor
- Clionsky Neuro Systems Inc.
Loss of Consciousness of Unspecified Duration, Cerebral Laceration and Contusion
The Clinical Research on the Relationship Between Circadian Rhythm and Gut Microbiota in TBI Patients
Microbiome studies may be highlighted as crucial in the development of sleep disorder for TBI patients. The microbiota-gut-brain connection may further provide an opportunity for microbiota manipulation to treat the TBI patients…
- Conditions
- Loss of Consciousness of Unspecified Duration, Cerebral Laceration and Contusion, Traumatic Brain Injury
- Trial name
- NCT02849028
- Testing
- sleep disorder
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Loss of Consciousness
Alteration of Temporal Organization of EEG Microstate Sequences During Propofol-induced Loss of Consciousness
Temporal dynamics of the EEG microstates show scale-free monofractal properties. This means that information is encoded in the same way at different scales.
- Trial name
- Fractal (NCT02125214)
- Testing
- Target Controlled Infusion system (Orchestra Base Primea, Fresenius, France)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Julien Maillard
Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With No Loss of Consciousness
The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury
The objective of this trial is to evaluate the effectiveness of cognitive rehabilitation in OIF/OEF service members with a history of mild traumatic brain injury and persistent (3-24 months post injury) cognitive complaints.
- Trial name
- SCORE (NCT01339806)
- Testing
- Cognitive Rehab, Brainworks, Informational Handout/Provider Visits
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Brooke Army Medical Center
General Anesthesia, Propofol Pharmacodynamics
Neuronal Inertia in Propofol Anesthesia
Loss and recovery of consciousness during propofol anesthesia seem to be mediated by different mechanisms beyond the actual effect-site concentration of anesthetic drug.
- Conditions
- General Anesthesia, Propofol Pharmacodynamics, Propofol Target Controlled Infusion, Loss of Consciousness and Recovery of Consciousness
- Trial name
- INERTIA (NCT01962285)
- Testing
- propofol targel controlled infusion
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Hydration, Loss of Consciousness
Effect of Chronic Oral Hydration in Patients With Recurrent Unexplained Syncope
Beneficial effect of chronic hydration with salt supplementation in patients with recurrent unexplained syncope is not established.
- Conditions
- Hydration, Loss of Consciousness, Neurocardiogenic Syncope
- Trial name
- NCT00143754
- Testing
- Hydration
- Sponsor
- University Hospital, Angers