Clinical trials: Loss of Control Eating
Pediatric Obesity, Binge-Eating Disorder
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and…
- Trial name
- NCT04701671
- Testing
- Observational (not including MRI scanning), Observational (including MRI scanning)
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, Weight Loss
Behavioral Mechanism of Energy Compensation With Exercise
Over 70% of Americans are either overweight or obese, putting them at risk for many chronic diseases including diabetes. Exercise is commonly used as a weight loss and weight loss maintenance strategy.
- Conditions
- Obesity, Weight Loss, Eating Behavior
- Trial name
- NCT04651218
- Testing
- exericse
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kyle Flack
Obesity; Impaired Glucose Regulation; Prediabetes; Type 2 Diabetes Mellitus
Time-Restricted Eating and Staple Food Reduction Combined With App-Supported Exercise for Weight and Glycemic Control
This multicenter, three-arm randomized controlled trial will evaluate the effects of early time-restricted eating and staple food reduction, each combined with an app-supported exercise intervention, on body weight and glycemic…
- Trial name
- TRE-SFR-EX (NCT07726615)
- Testing
- App-Supported Exercise Intervention, Staple Food Reduction, Early Time-Restricted Eating
- Volunteers
- 300 people
- Sponsor
- Peking University
Pediatric Obesity, Nutrition Disorders
The Intersection Between Loss of Control Eating and Obesity: The Role of Restriction and Food Reinforcement
This study aims to determine the relationships among loss of control eating, restriction, relative reinforcing value of high energy-dense food, and obesity risk.
- Conditions
- Pediatric Obesity, Nutrition Disorders, Binge Eating, Body Weight
- Trial name
- NCT05177705
- Testing
- Restricted access task, Structured Intake
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Subjective Well-being, Weight Loss
ME-WEL: eHealth Behaviour Change Intervention for Weight Management in Post-menopausal Women
In post-menopause, most women gain weight, and obesity rates are more prevalent in this particular group. In addition, there is an increased risk of cardiovascular disease, cancer, and diabetes.
- Conditions
- Subjective Well-being, Weight Loss, Self Esteem, Physical Activity
- Trial name
- ME-WEL (NCT05903157)
- Testing
- Control Group: Delivery of a health literacy flyer, Experimental Group: Weekly group sessions for weight management
- Where
- Portugal
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Obesity, Overweight
A Maintenance Program for the Be Fit Employee Wellness Program
This research study is being done: 1) to determine if the MGH Be Fit program helps employees to change their nutrition and exercise habits and lower their risk for chronic diseases, such as heart disease and diabetes and 2) to…
- Trial name
- NCT00707577
- Testing
- Internet-based maintenance program
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Loss of Control Eating
Loss of Control Eating Following Weight Loss Surgery
This study will test the effectiveness of two distinct behavioral treatments for loss of control eating following bariatric surgery: 1. Behavioral Weight Loss Treatment 2.
- Trial name
- NCT02259322
- Testing
- Standard-of-Care, Behavioral Weight Loss Treatment, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Loss-of-control Eating, Obesity/Overweight
Pharmacological and Behavioral Treatment After Bariatric Surgery: Acute (Stage 1)
This study will compare the effectiveness of behavioral and pharmacologic treatments, alone and in combination, for the treatment of loss-of-control eating and weight following bariatric surgery.
- Trial name
- NCT04599478
- Testing
- Naltrexone and Bupropion medication, Behavioral Weight Loss
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Yale University
Obesity, Eating Disorders
Efficacy and Safety of Rimonabant on Weight Loss and Frequency of Binge Episodes in Obese Patients
The primary objective is to assess the effect of rimonabant compared to placebo on weight loss over a period of 6 months when prescribed with a mild hypocaloric diet in obese patients with binge eating disorder.
- Trial name
- NCT00481975
- Testing
- rimonabant (SR141716)
- Where
- 7 sites in United States, Finland and 5 more
- Volunteers
- 289 people
- Sponsor
- Sanofi
Obesity
Effects of TRE With Lactobacillus Plantarum LP-KFY04 Supplementation on Overweight / Obese Individuals
With the improvement of the quality of life, multi-nutritional dietary intake today has provided people with a solid foundation for their health profiles.
- Trial name
- TRELO (NCT06423287)
- Testing
- Lactobacillus plantarum LP-KFY04
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Zhujiang Hospital
Overweight, Weight Loss
Study to Evaluate Benefit of ProbioSatys™ on Weight Reduction in Overweight Subjects
The study aims to evaluate the effects of ProbioSatys™ on body weight and related parameters in overweight subjects during a 12-week consumption period. In addition, tolerability and safety of ProbioSatys™ will be assessed.
- Trial name
- NCT03657186
- Testing
- ProbioSatys™
- Where
- 3 sites in Germany
- Volunteers
- 236 people
- Sponsor
- TargEDys
Binge Eating Behaviour, Eating Disorders
Biobehavioral Mechanisms of Activity and Loss of Control Eating in Children
Loss of control eating in children and adolescents is associated with a host of negative physical and psychological health outcomes and a prognostic marker for development of eating disorders.
- Conditions
- Binge Eating Behaviour, Eating Disorders, Physical Activity, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07823153
- Testing
- Go/No-go task, Visual food task, Emotion regulation task
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Obesity (Disorder), Bariatric Surgery
Impact of a Pro-diversity Gut Microbiota Diet After a Bariatric Surgery on Gut Microbiota, Eating Behaviour and Sensory Function
Bariatric surgery is the most effective treatment for long-term weight loss and reducing obesity-related health risks. It alters the gastrointestinal tract as well as metabolic and hormonal functions, influencing eating…
- Trial name
- BariaGut Taste (NCT07268508)
- Testing
- Nutritional counseling
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Obesity, Insulin Resistance
Study of Time-restricted Eating on Weight Loss.
This is a randomized controlled trial studying the effects of time-restricted eating (TRE) on weight loss in obese humans. Obesity is the number one risk factor for type 2 Diabetes Mellitus (T2DM), and numerous studies…
- Trial name
- TREAT (NCT03393195)
- Testing
- Time-restricted Eating plan, Consistent Meal timing plan
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Binge Eating Disorder, Binge Eating
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
The main purpose is to investigate the effectiveness of a 10-week multicomponent camp intervention to reduce BE behavior in children and adolescents and explore in a randomized controlled setting if a parent-based…
- Conditions
- Binge Eating Disorder, Binge Eating, Loss of Control Eating, Overweight , Obesity
- Trial name
- STOB (NCT07301541)
- Testing
- A 10-week multicomponent camp intervention for children, A BED intervention for parents
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 2 Diabetes Mellitus (T2DM), Hypertension
Eating Window and Sleep Disorders on Glycemic Control, Cardiovascular Risk, and Weight Loss
This project aims to offer a quantitative and qualitative nutritional approach, along with educational nutritional guidelines for participants with Non-Communicable Chronic Diseases.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Hypertension, Obesity and Type 2 Diabetes, Cardiovascular Diseases
- Trial name
- NCT06735859
- Testing
- Comparison of eating windows intervention
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Pregnancy Weight Gain, Eating Disorders
A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings in Pregnancy
Pregnancy is a time of heightened risk for disordered eating behaviors, which have been linked to adverse health outcomes in gestation, delivery, and the postpartum.
- Conditions
- Pregnancy Weight Gain, Eating Disorders, Perinatal Problems, Binge Eating
- Trial name
- NCT06129461
- Testing
- Single-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy
- Volunteers
- 130 people
- Sponsor
- University at Albany
Weight Loss
The Leeds Women's Wellbeing (LWW) Study
The purpose of this parallel design study is to assess the relative effects of two 12-week healthy eating dietary interventions: general healthy eating (Diet A) and general healthy eating combined with advice to increase fibre…
- Trial name
- LWW (NCT01539369)
- Testing
- Healthy eating diet (Diet A) or healthy eating diet combined with advice to increase fibre intake (Diet B) to at least 25g/day
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Loss of Control Eating, Attention Deficit/Hyperactivity Disorder
Effect of Stimulant Medication on Loss of Control Eating in Youth With Attention Deficit/Hyperactivity Disorder
Loss of control eating (LOC-E) in youth predicts the later development of full syndrome eating disorders, such as binge-eating disorder (BED), and therefore, could be a relevant target for prevention interventions.
- Trial name
- NCT05592119
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Nova Scotia Health Authority
Metabolic Health, Weight Loss
A Study to Evaluate the Effect of SlimBiotics L. Fermentum K8 Postbiotic on Weight Management and Metabolic Health Outcomes
This study is to evaluate the efficacy of a postbiotic supplement on weight management and metabolic health. This study will be conducted as a hybrid trial consisting of both in-person visits and virtual assessments.
- Conditions
- Metabolic Health, Weight Loss, Stress, Well-Being, Psychological
- Trial name
- NCT05912699
- Testing
- Slimbiotics Postbiotic
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Slimbiotics