Clinical trials: Loss of Muscle Strength
Low Muscle Mass, Low Muscle Strength
Nutrition Ameliorates the Muscle Loss of Pre-sarcopenia in Elderly
This study evaluates the effects of a 12-week leucine-enriched protein supplementation in adults aged 60 years and more. Participants will undergo assessments of muscle mass and function, as well as metabolic profiles in blood…
- Conditions
- Low Muscle Mass, Low Muscle Strength, Low Physical Function
- Trial name
- NCT07309120
- Testing
- Participants consume two sachets daily over a 12-week intervention period.
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Internet-Based Cognitive Behavioral Therapy
Efficacy of Internet-Based Cognitive Behavioral Therapy for Back Muscle Strength Loss, Chronic Pain, and Poor Patient Recovery Perceptions After Lumbar Fusion
This study aims to develop an Internet-based Cognitive Behavioral Therapy protocol for core muscle training, based on an understanding of factors impeding postoperative core muscle training in lumbar surgery patients.
- Trial name
- NCT07030582
- Testing
- Internet-delivered cognitive behavioral therapy, Basic Postoperative Care, Conventional Postoperative Care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Cancer, Hospitalizations
Multidomain Bedside Assessment of Short-Term Mortality and Readmission in Hospitalized Patients With Metastatic Cancer
This prospective observational study evaluated whether simple bedside assessments performed during an unplanned hospitalization were associated with short-term outcomes in adults with metastatic solid cancer.
- Conditions
- Cancer, Hospitalizations, Sarcopenia, Cachexia; Cancer; Sarcopenia
- Trial name
- PRO-HAND (NCT07167082)
- Testing
- Handgrip Strength Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 233 people
- Sponsor
- Ankara Etlik City Hospital
Cancer, Cancer Cachexia
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular…
- Conditions
- Cancer, Cancer Cachexia, Inflammation
- Trial name
- PROTECT (NCT04065815)
- Testing
- Resistance Training, WB-EMS, High-intensity interval training (HIIT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Muscle Loss, Physical Disability
Effects of High Protein Diet on Muscle Mass, Strength, and Physical Performance in Postmenopausal Women
Despite the importance of preventing muscle mass loss during senescence, only a few studies have investigated the relationship between diet and muscle mass in postmenopausal women.
- Trial name
- NCT03652584
- Testing
- High Protein Diet, Control Diet
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength
Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life
The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are: Is it feasible to measure hand grip strength as part of a clinic…
- Trial name
- PanFit (NCT07255001)
- Testing
- Hand grip strength assessments using a dynamometer
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Prostate Cancer
Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation
This is a study of HMB plus amino acids in older men with prostate cancer starting androgen deprivation therapy (ADT). The investigators hypothesize that the use of this nutritional supplementation will decrease the loss of…
- Trial name
- NCT01607879
- Testing
- Standard of care ADT + (HMB + arginine + glutamine), Standard of care ADT
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical College of Wisconsin
Muscle Loss, Muscle Weakness
Impact of Increased Protein Density Diet to Muscle Mass and Strength Among Mid-aged and Older Adults
The subjects of this intervention program are mainly based on community-dwelling mid-aged and older adults. The investigator's program will provide meals containing different proportionated protein.As this project is a double…
- Conditions
- Muscle Loss, Muscle Weakness, Fragility
- Trial name
- NCT03784456
- Testing
- 25% protein, 15% protein
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Diseases, Obesity
Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee
The purpose of this study is to determine whether a home-based exercise and weight control program applied to elderly overweight individuals with painful osteoarthritis of the knee, would result in pain reduction.
- Conditions
- Chronic Diseases, Obesity, Osteoarthritis, Pain
- Trial name
- NCT00126737
- Testing
- Weight Control Nutritional Program, Home-based exercise program
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- US Department of Veterans Affairs
Chronic Obstructive Pulmonary Disease
The Granheim COPD Study - Vitamin D and Strength Training
This study evaluates the effect of vitamin D supplementation on outcomes of 10 weeks progressive strength training in 100 ageing subjects (>45 years of age).
- Trial name
- NCT02598830
- Testing
- Vitamin D3
- Where
- Norway
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Muscle Mass
Strength Training Response of Muscle in GLP-1 Users
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function.
- Trial name
- STRONG-GLP (NCT07104539)
- Testing
- Strength Training, Wait first, then strength training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
End Stage Liver DIsease, Chronic Liver Failure
The Early Strength Training Program in Post-transplant Liver Cases
Liver transplantation (LT) is a current life-saving procedure performed as an open-abdominal surgery for patients with end-stage liver diseases (ESLD).
- Conditions
- End Stage Liver DIsease, Chronic Liver Failure, Liver Transplant Disorder, Muscle Loss
- Trial name
- NCT04546048
- Testing
- Strength Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Memorial Hospital Groups
Muscle Hypertrophy, Bone Mineral Density Loss
Combined Whey Protein and Collagen Supplementation in Resistance-Trained Men
This study tested whether taking whey protein together with collagen peptides would provide greater benefits for muscle and bone health compared to whey protein alone, collagen alone, or a placebo.
- Conditions
- Muscle Hypertrophy, Bone Mineral Density Loss, Resistance Training Adaptation
- Trial name
- NCT07171411
- Testing
- Whey Protein + Collagen, Whey Protein, Collagen Peptides
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Lower-Limb Strength, Muscular Endurance
Study of 15% Versus 30% Velocity Loss Thresholds During Bodyweight Squats and Their Effects on Strength and Endurance in Young Women
The goal of this clinical trial is to learn how two different velocity loss thresholds (15% and 30%) during bodyweight squats affect strength and endurance in non-athletic young women aged 18-25 years.
- Conditions
- Lower-Limb Strength, Muscular Endurance, Velocity-Based Resistance Training
- Trial name
- NCT07461701
- Testing
- Body-weight squat training (15% velocity loss threshold), Body-weight squat training (30% velocity loss threshold)
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
PreDiabetes, Older Adult
Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.
This is a 12-week randomized, controlled trial that seeks to examine the effect of Vivo on 1) change in lower extremity strength defined as number of chair stands done in 30 seconds and 2) change in average glycemic level (HbA1c)…
- Conditions
- PreDiabetes, Older Adult, Muscle Loss, Muscle Weakness
- Trial name
- NCT06458530
- Testing
- Vivo
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Impactiv, Inc.
Muscle Wasting, Obesity & Overweight
Testing the Efficacy, Safety, and PK of 20E in Patients With Obesity Who Are Starting Treatment With the GLP-1 Agonist Semaglutide for Weight Loss.
The goal of this clinical trial is to learn if BIO101 treatment can improve the muscle strength of participants males and females, aged 18 to 84 years old, suffering from obesity (BMI≥30) or overweight (BMI ≥ 27) with one or more…
- Conditions
- Muscle Wasting, Obesity & Overweight, Obesity
- Trial name
- OBA (NCT07411378)
- Testing
- BIO101, Semaglutide
- Volunteers
- 164 people
- Sponsor
- Biophytis