Clinical trials: Low; Birthweight
Hemodynamic Instability
Dobutamine Versus Placebo for Low Superior Vena Cava Flow in Newborns
Low systemic flow as measured by Doppler-echocardiography has been associated with poor neurological outcome. Yet, it has not been systematically evaluated whether the treatment of this hemodynamic condition is beneficial or not.
- Trial name
- NCT01605279
- Testing
- Dobutamine
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Adelina Pellicer
Malaria, Pregnancy Malaria
LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial
Objective: The aim of this study is to evaluate the impact of enhanced malaria cases detection using molecular testing (LAMP) on maternal and infant morbidity and mortality in a prospective study design.
- Conditions
- Malaria, Pregnancy Malaria, Malaria in Pregnancy
- Trial name
- LAMPREG (NCT03754322)
- Testing
- LAMP, Microscopy/RDT
- Where
- 4 sites in Canada, Ethiopia
- Volunteers
- 2,424 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Necrotizing Enterocolitis, Sepsis
Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants
OBJECTIVES: I. Compare the incidence of late onset sepsis and/or necrotizing enterocolitis and duration of hospitalization in low birth weight infants fed with fortified mother's milk supplemented with either fortified…
- Trial name
- NCT00005888
- Testing
- Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Center for Research Resources (NCRR)
Meconium Obstruction of Prematurity
Intestinal Fatty Acid Binding Protein in Very Low Birth Weight Infants With Meconium Obstruction
Urinary intestinal fatty acid binding protein (i-FABP), a marker of intestinal mucosal cell damage, has recently been proposed as a clinically useful measure in the early detection of necrotizing enterocolitis (NEC).
- Trial name
- NCT02864446
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Newborn Morbidity, Newborn Complication
Cord Blood Preptin Levels in Infants
In this study, cord blood preptin levels in infants with high or low birth weight will be compared to those in infants with normal birth weight.
- Trial name
- NCT06880003
- Testing
- During delivery, blood samples will be collected from the umbilical cord
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Stillbirth, Infant Mortality
Impact of Smoke-free Legislation on Early-life Mortality and Low Birth Weight in England
The purpose of this study is to investigate whether there has been a change in low birth weight and perinatal and infant mortality following the July 2007 introduction of a ban on smoking in public places and workplaces in…
- Conditions
- Stillbirth, Infant Mortality, Sudden Infant Death, Infant, Low Birth Weight
- Trial name
- NCT02039583
- Testing
- Smoke-free legislation
- Where
- United Kingdom
- Volunteers
- 10,291,118 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Birth Defect, Spontaneous Abortions
Nplate® Pregnancy Exposure Registry
US study to estimate the prevalence at birth of major birth defects (ie, those that cause significant functional or cosmetic impairment, require surgery, or are life-limiting) in children born to mothers who have received Nplate®…
- Conditions
- Birth Defect, Spontaneous Abortions, Low Birth Weight
- Trial name
- NPER (NCT02090088)
- Testing
- Not applicable- observational study
- Volunteers
- 4 people
- Sponsor
- Amgen
Preterm Infant, Very Low Birth Weight Infant
Lactoferrin Infant Feeding Trial - LIFT_Canada
This is a multicentre, phase III, 2-arm, masked randomized controlled trial. The primary hypothesis is that oral bovine lactoferrin (bLF), through its antimicrobial, antioxidant and anti-inflammatory properties, will reduce the…
- Conditions
- Preterm Infant, Very Low Birth Weight Infant, Morbidity;Newborn
- Trial name
- NCT03367013
- Testing
- Bovine Lactoferrin, No Bovine Lactoferrin added
- Where
- 9 sites in Canada
- Volunteers
- 453 people
- Sponsor
- Dr. Elizabeth Asztalos
Preterm
Early Childhood (2-year) Outcomes Among Former VLBW From the ReDiMOM Trial
The goal of this study is to determine the long-term outcomes associated with an economic intervention that was provided to encourage mother's of very premature infants to provide mother's own milk.
- Trial name
- NCT07702318
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- Rush University Medical Center
Low Birth Weight
Probiotics-Supplemented Feeding in Extremely Low Birth Weight Infants
The overall purpose of this research is to test whether adding a supplement to the feeding of extremely low birth weight infant (infants weighing less than 2 pound 2 oz at birth) will help him/her achieve full feeding faster and…
- Trial name
- PAS (NCT01164124)
- Testing
- Probiotic supplementation (Lactobacillus rhamnosus GG and Bifidobacterium infantis)
- Where
- 3 sites in United States
- Volunteers
- 101 people
- Sponsor
- Vermont Oxford Network
Low Birthweight, Preterm
Enhancing the Survival of Low Birth Weight Infants in Low-Resource Settings
Kangaroo Care, which includes skin-to-skin contact, exclusive breastfeeding, and timely follow-up, is a proven method to reduce neonatal morbidity and mortality in low-resource settings where the risks of prematurity, neonatal…
- Conditions
- Low Birthweight, Preterm, Kangaroo Mother Care
- Trial name
- NCT06937580
- Testing
- Peer Support and Baby Box
- Where
- 2 sites in Ghana
- Volunteers
- 328 people
- Sponsor
- University of South Carolina
Preterm Infant, Early-Onset Neonatal Sepsis
Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants
This study evaluates the utility of placental/umbilical cord blood (PUCB) to perform the baseline workup testing for EONS in Very Low Birth Weight Infants: CBC (Complete Blood Count) with differential, Immature/Total ratio (I/T…
- Conditions
- Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
- Trial name
- NCT03694613
- Testing
- Placental/Umbilical Cord Blood sample
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Very Low Birth Weight Infants
Oropharyngeal Colostrum for Immune Stimulation in Very Low Birth Weight Infants
Colostrum, mothers' early breastmilk, contains multiple factors that provide immune protection to very low birth weight (VLBW) infants, a population at high risk for hospital-acquired infections.
- Trial name
- NCT01443091
- Testing
- application of mother's own colostrum, application of sterile water
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Low Birth Weight Among Neonates
Randomized, Controlled Trial of Kangaroo Mother Care in Increasing the Rate of Weight Gain Among Neonates
A randomized, controlled trial of Kangaroo Mother Care (KMC) to determine the effectiveness in increasing the rate of weight gain among low birth weight neonates.
- Trial name
- NCT02085382
- Testing
- Kangaroo Mother Care, Conventional Mother Care
- Where
- Philippines
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of the Philippines