Clinical trials: Low Back Disorder
Chronic Pain, Intractable Pain
Study to Evaluate Automated Intensity Management in Patients Undergoing a BSC SCS Temporary Trial
The purpose of the study is to assess the feasibility of using information extracted from physiologic signals to automatically adjust stimulation in patients undergoing Spinal Cord Stimulation (SCS).
- Conditions
- Chronic Pain, Intractable Pain, Low Back Pain, Pain, Neuropathic
- Trial name
- AIM (NCT04909593)
- Testing
- Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston Scientific Corporation
Low Back Pain
Duration of Spinal Manipulation Effects as Influenced by Orthotics
Purpose of study: To assess the effects of wearing custom orthotics as opposed to placebo foot inserts on the duration of chiropractic correction of spinal fixations and muscle imbalances using applied kinesiology techniques.
- Trial name
- NCT01704807
- Testing
- foot orthotics
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Logan College of Chiropractic
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Low Back Pain
A 12-week Pilates Programme for Low Back Pain: Perceived and Actual Outcomes
Pilates has emerged as a prominent exercise therapy gaining recognition among healthcare professionals for its potential benefits in managing low back pain (LBP).
- Trial name
- NCT06395493
- Testing
- Pilates Group, Exercise Group, Control Group
- Volunteers
- 90 people
- Sponsor
- University of Malta
Postpartum Depression, Pregnancy Related
Clinical Pilates and Prenatal Education on Perinatal Depressive Symptoms
This study evaluated whether a combined program of supervised Clinical Pilates Exercise and structured Prenatal Education, added to routine antenatal care, reduces perinatal depressive symptoms compared with routine antenatal…
- Conditions
- Postpartum Depression, Pregnancy Related, Low Back Pain, Labor Pain
- Trial name
- CPE-PE (NCT07647809)
- Testing
- Clinical Pilates Exercise, Prenatal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Neck Pain, Low Back Pain
Turkish Version of the Usefulness, Satisfaction, and Ease of Use Questionnaire (USE): Reliability and Validity
In recent years, numerous technological products and devices have been developed in rehabilitation through advances in biomedical technology.
- Conditions
- Neck Pain, Low Back Pain, Biomedical Technology, Validation
- Trial name
- NCT07159724
- Testing
- back up, mollii-suit, compex, tens
- Volunteers
- 220 people
- Sponsor
- Hacettepe University
Spinal Stenosis, Low Back Pain
The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Fusion The IVANOS-study
The average life expectancy in Denmark is increasing resulting in an increasing part of the population having age-related disease, ex lumbar spinal stenosis (LSS).
- Trial name
- IVANOS (NCT02895555)
- Testing
- i-FACTOR, Allograft
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Spine Centre of Southern Denmark
Conditions
Association Between TMD and LBP Back Pain
Investigate the relationships between temporomandibular disorder and low back pain
- Trial name
- NCT03139175
- Testing
- balance assessment with Biodex balance system
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Chronic Low Back Pain
Chronic Low Back Pain Research Project
The purpose of this study is to determine whether gabapentin is efficacious as an analgesic for chronic low back pain.
- Trial name
- NCT00108550
- Testing
- gabapentin
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- US Department of Veterans Affairs
Low Back Pain
Internet App to Self-Manage Occasional Low Back Pain
Nonspecific low back pain (NLBP) is the diagnosis for 85% of low back pain sufferers with no underlying medical cause (e.g., herniated disc, spinal stenosis) that requires physician care.
- Trial name
- BackPain2 (NCT01950091)
- Testing
- FitBack on-line intervention, Alternative Website Control
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Chronic Low Back Pain
Treatment of Low Back Pain in Patients With End-stage Renal Disease on Hemodialysis
The purpose of this study is to determine whether a physiotherapeutic intervention is effective in the treatment of low back pain in hemodialysis patients
- Trial name
- NCT01095783
- Testing
- physiotherapeutic intervention, control
- Where
- Brazil
- Sponsor
- Federal University of São Paulo
Low Back Pain, Neuralgia
Primary Care Identification Of Patients With Chronic Neuropathic Low Back Pain Study
A0081256 is a prospective, open-label, multi-centre European study designed to raise awareness and enhance the diagnosis of patients with chronic low back pain with a neuropathic pain component in primary care who are refractory…
- Trial name
- PINPOINT (NCT01298466)
- Testing
- Pregabalin
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Degenerative Disc Disease
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain
The primary purpose of this study is to evaluate the efficacy of rexlemestrocel-L+HA compared to control in reducing low back pain at 12 months post-treatment and safety of a single injection of rexlemestrocel-L+HA injected into…
- Trial name
- HyaluronicAcid (NCT06325566)
- Testing
- Rexlemestrocel-L + HA mixture, Saline
- Where
- 40 sites in United States
- Volunteers
- 300 people
- Sponsor
- Mesoblast, Ltd.
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Persistent Lower Back Pain, Sleep Disturbance
What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physiotherapy Setting?
The goal of this qualitative is to understand the views and opinions of patients with persistent lower back pain patients who are awaiting physiotherapy treatment with regards sleep their sleep health.
- Conditions
- Persistent Lower Back Pain, Sleep Disturbance, Lower Back Pain, Chronic Low-back Pain
- Trial name
- NCT06094517
- Testing
- Interview
- Volunteers
- 10 people
- Sponsor
- Sheffield Hallam University
Sprain of Sacroiliac Ligament, Low Back Pain
Ultrasound-guided Sacroiliac Joint Radiofrequency Ablation: A Pilot Study
The sacroiliac (SI) joint is a common source of low back pain. Radiofrequency ablation (RFA) can be used to treat low back pain from the SI joint , and is often recommended by physicians to provide long lasting pain relief.
- Conditions
- Sprain of Sacroiliac Ligament, Low Back Pain, Osteoarthritis Nos, of Sacroiliac Joint
- Trial name
- NCT02335190
- Testing
- Radiofrequency ablation, Sensory block, Lidocaine
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Western University, Canada
Chronic Low-back Pain, Insomnia
Mobile App-delivered Sleep Therapy (SleepFix) for Individuals With Chronic Low Back Pain and Insomnia
The goal of this clinical trial is to assess the efficacy of a digital behavioral therapy for insomnia (dBTi) in people with chronic low back pain and insomnia.
- Trial name
- SleepBack (NCT05846087)
- Testing
- sleep retraining therapy, sleep health education modules
- Where
- Australia
- Volunteers
- 106 people
- Sponsor
- Woolcock Institute of Medical Research
Prevalence of Germs, Spinal Surgery
Evaluation of the Prevalence of Germs Slow Growth in the Intervertebral Disc (IVD) During Spinal Surgery
Low back pain is one of the most frequent reasons for consultation in rheumatology. There is a strong correlation between low back pain, and the presence of a type of Modic 1 signal on MRI.
- Conditions
- Prevalence of Germs, Spinal Surgery, Anterior Disc Disease, Modic 1
- Trial name
- DISCO-PROP (NCT02892617)
- Testing
- Bacteriological analysis of disc
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sciatica
Energy Specific Far Infrared Radiation Treatment for Sciatica
A preliminary study to determine the use of far infrared radiation for the treatment of back pain
- Trial name
- NCT00573807
- Testing
- Far Infrared Radiation (5μm to 20μm wavelength)
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- GAAD Medical Research Institute Inc.
Pain, Chronic Pain
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in subjects suffering from severe chronic low back pain (LBP) who are taking WHO Step III…
- Conditions
- Pain, Chronic Pain, Low Back Pain, Neuropathic Pain
- Trial name
- NCT00986258
- Testing
- Tapentadol Prolonged Release
- Where
- 27 sites in Belgium, Czechia and 6 more
- Volunteers
- 136 people
- Sponsor
- Grünenthal GmbH