Clinical trials: Low Back Disorder, open to volunteers
Low Back Pain, Spine Disease
Effect of an Interdisciplinary Spine Rehabilitation Program
The goal of this research project is to evaluate the effectiveness of the current interdisciplinary rehabilitation program (Revita) and follow-up trajectory for chronic lumbar spine disorders in the University Hospitals Leuven.
- Trial name
- PROGRESS (NCT06030570)
- Testing
- Rehabilitation program (Revita)
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Chronic Low-back Pain (cLBP), Non Specific Chronic Low Back Pain
TECAR Therapy in Chronic Back Pain
The goal of this clinical trial is to learn whether adding high-intensity electromyostimulation (Hi-EMS) to capacitive and resistive electric transfer (TECAR) therapy improves pain and functional performance in adults with…
- Trial name
- NCT07821021
- Testing
- TECAR Therapy plus Hi-EMS, Tecar therapy alone
- Volunteers
- 37 people
- Sponsor
- University of Hartford
Sciatica, Lumbosacral Radiculopathy
Three CT Signs of Nerve-root Suffering in Low-back Sciatica: a Study of Their Frequency in Patients Referred for CT-guided Nerve-root Infiltration.
Retrospective, observational, single-centre study conducted at Nice University Hospital (Pasteur 2), Department of Diagnostic and Interventional Radiology.
- Conditions
- Sciatica, Lumbosacral Radiculopathy, Low Back Pain
- Trial name
- NCT07690449
- Testing
- Pre-infiltration lumbar planning CT scan - reading of the three nerve-root signs
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP)
Comparing Non-Medicine Strategies for Improving Low Back Pain
The goal of this clinical trial is to help veterans manage high-impact chronic pain (HICP) in the lower back. The trial will use a program, ENCompaSS (Education, Navigated Care, and Supported Self-Management) designed to reduce…
- Trial name
- NCT07679178
- Testing
- ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care
- Where
- United States
- Volunteers
- 530 people
- Sponsor
- Duke University
Low Back Pain, Kinesiophobia (Fear of Movement)
Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain
Brief Summary The goal of this clinical trial is to learn if MUSIC CARE©, a music-based therapy tool, can improve the physical abilities of people with chronic low back pain (back pain that lasts more than 3 months).
- Conditions
- Low Back Pain, Kinesiophobia (Fear of Movement), Chronic Low-back Pain (cLBP)
- Trial name
- LOMBALZIC' (NCT07731204)
- Testing
- Receptive Music Therapy
- Where
- France
- Volunteers
- 34 people
- Sponsor
- LNA SANTE
Low Back Pain, Neck Pain
Pre-Visit AI Symptom-Checking and Shared Decision-Making in Spine Physical Therapy
Artificial intelligence (AI) symptom-checking tools, including large language models such as ChatGPT, are increasingly used by patients before they seek care.
- Conditions
- Low Back Pain, Neck Pain, Radiculopathy
- Trial name
- NCT07733752
- Testing
- re-visit AI symptom-checker use
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Myofascial Pain Syndrome - Lower Back, Myofascial Pain Syndrome - Neck
Low-Energy Ultrasound, Electrical and Magnetic Field Stimulation in Therapy-Resistant Myofascial Pain Syndrome
Sonodyn is an investigational device that within this clinical investigation is intended for use in patients suffering from low back pain, tension headache or neck pain, originating from therapy-resistant myofascial pain…
- Conditions
- Myofascial Pain Syndrome - Lower Back, Myofascial Pain Syndrome - Neck, Myofascial Pain Syndrome - Tension Headache
- Trial name
- NCT05851326
- Testing
- Active Sonodyn
- Where
- 6 sites in Austria, Switzerland
- Volunteers
- 126 people
- Sponsor
- Sobet AG
Diseases [C] - Musculoskeletal Diseases [C05
PRGF-ENDORET® Infiltrations in the Treatment of Low Back Pain.
The goal of this clinical trial is to evaluate the efficacy of PRGF in reducing pain and improving patients' quality of life. Researchers will compare an experimental drug (Plasma Rich in Growth Factors) to a control…
- Trial name
- NCT06715085
- Testing
- Plasma Rich in Growth Factors (PRGF), Corticosteroid solution (Celestone Cronodose suspension for injection) in saline solution.
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Biotechnology Institute IMASD
Chronic Low-back Pain (cLBP), Urinary Incontinence (UI)
Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence
Urinary incontinence (UI), Chronic low back pain (CLBP) in women are prevalent and often coexist. Multiple conditions when coexist, it leads to reduced Quality of life in turn causing physical and mental impairment.
- Conditions
- Chronic Low-back Pain (cLBP), Urinary Incontinence (UI), Pelvic External Myofascial Mobilisation, Myofascial Techniques
- Trial name
- NCT07351851
- Testing
- PEMM with Theragun, Active Comparator: Control
- Where
- Qatar
- Volunteers
- 200 people
- Sponsor
- Hamad Medical Corporation
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Degenerative Disc Disease, DDD
Biologic Injection For Adults With Lumbar Disc Herniation
The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation.
- Conditions
- Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar
- Trial name
- BMAC (NCT07386548)
- Testing
- Bone Marrow Aspirate Concentrate (BMAC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Weill Medical College of Cornell University
Non Specific Low Back Pain
Effects of Pain Neuroscience Education on Pain, Kinesiophobia in Patients With Non Specific Low Back Pain
Chronic non-specific low back pain (NSLBP) is a highly prevalent musculoskeletal condition and a leading cause of disability worldwide.
- Trial name
- NCT07460011
- Testing
- Core stabilization exercises, Pain neuroscience education + core stabilization
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Chronic Low Back Pain (CLBP), Nociplastic Pain
PRT for Chronic Low Back Pain
The goal of this clinical trial is to learn whether Pain Reprocessing Therapy (PRT) is a feasible and acceptable treatment to complete for working-age adults (ages 18-65) with chronic low back pain.
- Trial name
- NCT07696741
- Testing
- Pain Reprocessing Therapy, Monitoring and Education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Virtual Reality, Kinesiophobia
Can Virtual Reality Exercise Help Restore Both Body and Mind in Chronic Low Back Pain
The goal of this clinical trial is to learn if an immersive virtual reality (VR) exercise program can help reduce back pain and improve physical function and psychological well-being in adults with chronic low back pain.
- Conditions
- Virtual Reality, Kinesiophobia, Chronic Low Back Pain (CLBP), Central Sensitization
- Trial name
- NCT07207083
- Testing
- Immersive Virtual Reality-based Exercise (FitXR, Meta Quest 3s), Conventional Exercise Program (Matched Exercise, without VR)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- dongmin kang
Chronic Low Back Pain
Virtual Reality-Based Rehabilitation Versus Conventional Therapy in Patients With Chronic Low Back Pain
This study aims to evaluate the effectiveness of rehabilitation using virtual reality compared with conventional physiotherapy in patients with chronic low back pain.
- Trial name
- NCT07463105
- Testing
- Virtual Reality-Assisted Rehabilitation, Conventional Rehabilitation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- University of Rzeszow
Cervical Radiculopathy
Relationship Between Craniovertebral Angle, Lumbar Proprioception, and Trunk Muscle Strength in Cervical Radiculopathy
The study aimed to Investigate the relation of cranio-vertebral angle with lumbar proprioception in patients with cervical radiculopathy.
- Trial name
- NCT07240090
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Basma Ashraf Ali Mohamed
Chronic Low-back Pain, Chronic Pain
Chromatic Retinal Stimulation to Reduce Chronic Pain and Pain Sensitivity
Participants with chronic pain conditions including chronic low back pain and fibromyalgia may benefit from light stimuli presented to the retina to reduce chronic pain severity and pain sensitivity.
- Conditions
- Chronic Low-back Pain, Chronic Pain, Fibromyalgia
- Trial name
- NCT05956067
- Testing
- Green Light stimulation, Equal Energy White stimulation, S-cone modulating white light
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine