Clinical trials: Low Back Pain, Chronic, open to volunteers
Chronic Non-Specific Low Back Pain, Chronic Non-specific Neck Pain
Predictive Variables of Outcome in Subjects With Chronic Rachialgia Referred to Different Pathways of Physiotherapy.
The aim of this study is to investigate the predictive value of various biopsychosocial variables on the outcomes of subjects with chronic spinal pain undergoing public health rehabilitation pathways.
- Trial name
- PRE-CBP (NCT06915896)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Low Back Pain, After Lumbar Spine Surgery
Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery
Chronic low back pain after spinal surgery is a complex and disabling condition influenced by biopsychosocial factors. Cognitive Functional Therapy (CFT) is a promising intervention targeting these multidimensional aspects.
- Conditions
- Chronic Low Back Pain, After Lumbar Spine Surgery, Failed Back Surgery Syndrome (FBSS)
- Trial name
- NCT07576062
- Testing
- CFT
- Volunteers
- 90 people
- Sponsor
- Centro Universitário Augusto Motta
Overweight or Obesity, Chronic Low-back Pain
Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT
Chronic low back pain (CLBP) is the most expensive cause of workrelated disability: it causes the highest number of years lived with disability.
- Trial name
- BO2WL (NCT05811624)
- Testing
- Physiotherapy intervention, including behavioral weight reduction program combined with pain neuroscience education and cognition-targeted exercise therapy., Physiotherapy intervention, including pain neuroscience education and cognition-targeted exercise therapy alone.
- Where
- 2 sites in Belgium, Switzerland
- Volunteers
- 252 people
- Sponsor
- Vrije Universiteit Brussel
Low Back Pain, Chronic Low Back Pain
Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome
The aim of the study is to evaluate the effects of biofeedback-assisted stabilization training and conventional therapy on pain perception, balance, spinal mobility, functional performance, physical activity, stress level, and…
- Trial name
- NCT07463729
- Testing
- Standard Rehabilitation, Biofeedback Ultrasonography
- Where
- Poland
- Volunteers
- 110 people
- Sponsor
- University of Rzeszow
Chronic Sacroiliac Joint Pain
Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain
This is a single-center, randomized, open-label, pilot study in adult subjects with chronic sacroiliac joint (SIJ) pain. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº…
- Trial name
- NCT06935539
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Low Back Pain, Chronic Low-back Pain (cLBP)
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)
This study tests whether a virtually delivered integrated tai chi, qigong, and meditation program, added to usual care, improves chronic low back pain, disability, quality of life, and healthcare costs compared with usual care…
- Trial name
- NCT07772154
- Testing
- Virtually Delivered Integrated Tai Chi, Qigong, and Meditation (VDTQM)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- New York Medical College
Chronic Nonspecific Low Back Pain
Effects of SIS Therapy in Individuals With Chronic Nonspecific Low Back Pain
Brief Summary - buraya yapıştırın Chronic nonspecific low back pain is a common condition that can cause pain, limitations in daily activities, and reduced quality of life.
- Trial name
- NCT07839169
- Testing
- SIS Therapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Chronic Low Back Pain, Foot Reflexology
Foot Reflexology for Chronic Low Back Pain
The aim of this 2-year randomized, double-blinded clinical trial is to investigate the effect of 6 or 12 sessions of weekly 45-minute to 1-hour foot reflexology interventions on physical function and symptoms, pain…
- Trial name
- NCT06828016
- Testing
- foot reflexology, usual foot care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Fu Jen Catholic University Hospital
Low Back Pain, Functional Reach
The Relationship Between Transversus Abdominis Muscle Architecture and Upper Extremity Function in Patients With Chronic Low Back Pain
Core stability is the ability to control the position and movement of the trunk for optimal production, transfer, and control of forces in the upper and lower extremities during functional activities.
- Conditions
- Low Back Pain, Functional Reach, Scapular Dyskinesis, Core Muscles
- Trial name
- NCT07474610
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ilayda Dilan Isik
Chronic Low Back Pain (CLBP), Low Back Pain
Chronic Low Back Pain and Osteopathic Manipulation Treatment
The goal of this clinical trial is to learn if adding Osteopathic Manipulative Therapy (OMT) to the usual medical care provided at the VA (usual VA care) improves treatment outcomes in individuals with chronic low back pain…
- Trial name
- NCT07161661
- Testing
- Usual VA Care, Osteopathic manipulative treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Edward Hines Jr. VA Hospital
Chronic Low-back Pain, Vertebrogenic Pain Syndrome
Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
Compile real-world outcomes of commercially approved Intracept™ Intraosseous Nerve Ablation Systems in the treatment of patients diagnosed with vertebrogenic pain.
- Trial name
- IMPROVE (NCT06827262)
- Testing
- Intracept™ Intraosseous Nerve Ablation
- Where
- 22 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Scientific Corporation
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Low Back Pain, Opioid Use
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based…
- Trial name
- NCT05607381
- Testing
- Meditation, Usual care
- Where
- 2 sites in United States
- Volunteers
- 188 people
- Sponsor
- University of Utah
Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction
Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain
This single-blind randomized controlled trial will aim to determine the effectiveness of a connective tissue dry needling (CTDN) technique, in reducing pain and improving function in individuals with chronic mechanical low back…
- Conditions
- Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction, Mechanical Low Back Pain
- Trial name
- NCT07345871
- Testing
- Connective tissue dry needling, Exercise therapy
- Volunteers
- 42 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Chronic Low Back Pain (CLBP)
A Superiority Trial of Radiofrequency Ablation for Low Back Pain
The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure.
- Trial name
- ASTRAL (NCT07222462)
- Testing
- Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Washington
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
End-Stage Renal Disease
The Effect of Magnetic Stimulation on Low Back Pain Relief and Muscle Mass Maintenance in Patients With ESRD
To determine the effectiveness of magnetic stimulation application on alleviating back pain and maintaining muscle mass in patients with end-stage renal disease.
- Trial name
- NCT06982573
- Testing
- Effects of applying magnetic stimulation
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Bundang CHA Hospital
Lumbago
Treatment of Mechanical Low Back Pain With High-Intensity Focused Ultrasound (HIFU)
High-intensity focused ultrasound (HIFU) is an emerging technology that allows for the targeted thermal ablation of deep tissues in a non-invasive manner, by concentrating acoustic energy on the target nerve, whilst preserving…
- Trial name
- NCT07467408
- Testing
- High-Intensity Focused Ultrasound of the medial lumbar branch
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Consorci Sanitari de Terrassa
Chronic Low-back Pain, Back Disorder
Movement Performance in Persons With Chronic Back Pain
The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance…
- Trial name
- NCT06891625
- Testing
- SMT, ET, OLP
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet