Clinical trials: Low Back Pain, completed
Chronic Low-back Pain
Evaluation of the Benefit and Safety of Localized Tissue Hydration in the Management of Chronic Low Back Pain
The purpose of this study is to evaluate the benefit of Localized Tissue Hydration associated with standard management of chronic common low back pain, in terms of improvement in the numerical verbal scale score at 6 months.
- Trial name
- HTL-LOMB (NCT06471998)
- Testing
- Sodium Chloride injection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Acute Low Back Pain
A Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of DW340 in Patients With Acute Low Back Pain
A Single-Center, Randomized, Double-Blind, Parallel, Pilot Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Pelubiprofen/Eperisone in Patients with Acute Low Back Pain
- Trial name
- NCT03424707
- Testing
- DW340(pelubiprofen/eperisone), Pelubi(pelubiprofen)
- Volunteers
- 45 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Safety and Efficacy With NOVOCART® Disc Plus (ADCT) for the Treatment of Degenerative Disc Disease in Lumbar Spine
NOVOCART® Disc plus is being investigated to explore its clinical applicability, safety and efficacy in the repair of a herniated disc with an indication for an elective sequestrectomy, and of the adjacent degenerated disc, if…
- Trial name
- NDisc (NCT01640457)
- Testing
- NOVOCART® Disc plus, NOVOCART® Disc basic
- Where
- 10 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Tetec AG
Low Back Pain
Acupuncture in Acute Nonspecific Low Back Pain
Acute low back pain is a common disorder in general practice. Some general practitioners (GPs) treat acute low back pain (LBP) with acupuncture, despite lacking evidence of its effectiveness for this condition.
- Trial name
- Acuback (NCT01439412)
- Testing
- Acupuncture and standard treatment, Standard treatment in general practice
- Where
- Norway
- Volunteers
- 185 people
- Sponsor
- University of Oslo
Spondyloarthropathy
Rehabilitative Therapy and Pridinol in Patients With Lumbar Spondylarthrosis and Chronic Low Back Pain
Spondyloarthrosis is a degenerative disease involving the intervertebral disc, vertebral bodies, and adjacent soft tissues. Treatment aims to slow disease progression and manage symptoms through an interdisciplinary approach.It…
- Trial name
- NCT06252064
- Testing
- Rehabilitation + Drug therapy, Rehabilitation, Drug therapy
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Palermo
Back Pain, Balance
Examination of Pain in Individuals With Non-Specific Lack Pain
The aim of this study is to examine the relationship between pain, and balance, proprioception sensation in the knee, erector spinae and multifidus muscle strength in individuals with non-specific low back pain.
- Conditions
- Back Pain, Balance, Proprioception
- Trial name
- NCT05511805
- Testing
- Visual Analogue Scale (VAS),, Oswestry Low Back Pain and Disability Questionnaire, Functional Low Back Pain Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Saglik Bilimleri Universitesi
Physical Therapy, Chronic Low Back Pain
Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 1)
The purpose of this study is to investigate the effect on QoL, PI and the AROM° in patients with non-specific chronic low back pain.
- Conditions
- Physical Therapy, Chronic Low Back Pain, Quality of Life, Range of Motion
- Trial name
- CLBP (NCT03322956)
- Testing
- Physioterapy intervention
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Lumbar Disc Herniation, Lumbar Disc Disease
Effects of Kinesio Taping on Pain, Endurance, Proprioception, Mobility and Disability in Lumbar Disc Herniation
In addition to the physical therapy program, taping was applied to 90 patients diagnosed with lumbar disc herniation. 90 patients were randomized into 3 groups.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Chronic Pain
- Trial name
- NCT06777095
- Testing
- Routine Treatment + I Taping, Routine Treatment + Star Taping, Routine Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sevtap Günay
Chronic Pain, Lower Back Pain Chronic
Lumbar Injectrode Feasibility Evaluation
The goal of this non-significant risk study is to determine whether stimulation with transcutaneous waveforms applied on the outside of the body and subcutaneously conducted to the lumbar medial branch nerve elicits visible (via…
- Trial name
- LIFE (NCT06206356)
- Testing
- PNS Injectrode F1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuronoff, Inc
Chronic Low Back Pain
EFFects of EXPosure and Cognitive-behavioural Therapy for Chronic BACK Pain
The overall aim of the present study is to compare two different psychological methods, Cognitive Behavioural Therapy (CBT) and Graduated Exposure in vivo (EXP) in the treatment of chronic back pain with regard to effectiveness…
- Trial name
- EFFECT-BACK (NCT05294081)
- Testing
- Exposure therapy, Cognitive behavioral therapy
- Where
- 5 sites in Germany
- Volunteers
- 392 people
- Sponsor
- University of Kaiserslautern-Landau
Low Back Pain
Pain Experience in Individuals With Chronic Low Back Pain
Low back pain is a very common musculoskeletal condition that affects many people each year regardless of age, gender, and ethnicity.
- Trial name
- NCT03972332
- Testing
- Quantitative Sensory Testing
- Where
- United Kingdom
- Volunteers
- 97 people
- Sponsor
- University of Nottingham
Low Back Pain
Comparison of Egoscue Versus Pilates Exercises in Patient With Mechanical Low Back Pain
Mechanical low back pain arises intrinsically from the spine, intervertebral disc,or surrounding soft tissues.It is causes by muscular spasm, and other soft tissue injuries.
- Trial name
- NCT06461494
- Testing
- baseline treatment
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Facet Syndrome of Lumbar Spine
RAMBAM 021: Safety and Initial Feasibility of the Neurolyser XR for the Treatment of Chronic Low Back Pain
Single arm pilot study to evaluate the safety and initial feasibility of the Neurolyser XR, a high intensity focused ultrasound device, for non-invasive treatment of axial chronic low back pain
- Trial name
- NCT04519541
- Testing
- Non-Invasive Thermal Ablation of the Medial Branch Nerves using the Neurolyser XR
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.
Chronic Low Back Pain
Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective of this study is to evaluate the analgesic efficacy and safety of HYD tablets 20 to 120 mg once-daily dose compared to placebo in subjects with moderate to severe chronic low back pain uncontrolled by their…
- Trial name
- NCT01452529
- Testing
- Hydrocodone bitartrate q24h film-coated tablets
- Where
- 102 sites in United States
- Volunteers
- 905 people
- Sponsor
- Purdue Pharma LP
Low Back Pain
Belt Squat Training for Non-Specific Low Back Pain
The purpose of this project is to investigate the feasibility of using belt squat as an exercise intervention for people with chronic low back pain.
- Trial name
- NCT06594731
- Testing
- Hip belt squat training
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mathias Kristiansen
Pain
Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain
The aim of the study is to determine if an experimental drug, ralfinamide, relieves your neuropathic low back pain, and if it demonstrates superiority to placebo, a "dummy" or sugar pill that contains no active medication.
- Trial name
- NCT01019824
- Testing
- Ralfinamide
- Where
- United Kingdom
- Volunteers
- 411 people
- Sponsor
- Newron Pharmaceuticals SPA
Low Back Pain, Sex Disorder
Sexual Disability in Low Back Pain and Physiotherapy
A treatment centered on the person uses an approach capable of considering all the components of disability, from a physical, psychological and social point of views.
- Trial name
- NCT05636423
- Testing
- Survey
- Where
- Italy
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Low Back Pain
Additional Effect of Pain Neuroscience Education to Spinal Manipulative Therapy in Chronic Low Back Pain
Objectives: The primary objective will be to investigate the additional effect (immediate and after one-month follow up) of pain neuroscience education (PNE) to Spinal Manipulative Therapy (SMT) on primary outcomes of pain…
- Trial name
- NCT03356886
- Testing
- Spinal Manipulative Technique, Pain Neuroscience Education
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- University of Sao Paulo
Pain, Intractable, Breakthrough Pain
Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain
The purpose of this study is to determine whether the local anesthetic bupivacaine delivered intrathecally in small doses via PTM self-administered boluses significantly improves the breakthrough pain and functional status of…
- Conditions
- Pain, Intractable, Breakthrough Pain, Chronic Pain
- Trial name
- NCT02886286
- Testing
- Bupivacaine, Opioid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University Hospitals Cleveland Medical Center
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