Clinical trials: Low Back Pain, completed
Nonspecific Chronic Low Back Pain
Patient Education and Motor Control Exercise Among Rural Community-dwelling Adults With Chronic Low Back Pain
Low back pain (LBP) is the leading cause of years lived with disability globally with increasing concern about its impact in low- and middle-income countries like those situated in Africa where most people are living in rural…
- Trial name
- NCT03393104
- Testing
- Motor Control Exercise, Patient Education
- Where
- Nigeria
- Volunteers
- 120 people
- Sponsor
- Bayero University Kano, Nigeria
Pain, Low Back Pain
An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain Participants
The purpose of this study is to evaluate the efficacy, safety and to explore the pharmacokinetics (how drugs are absorbed in the body, how they are distributed within the body and how they are removed from the body over time) of…
- Conditions
- Pain, Low Back Pain, Back Pain, Osteoarthritis, Knee
- Trial name
- NCT01124604
- Testing
- Tapentadol Hydrochloride
- Where
- 19 sites in Japan
- Volunteers
- 91 people
- Sponsor
- Janssen Pharmaceutical K.K.
Low Back Pain
Effectiveness of a Short, Intensive and Standardised Spa Therapy for Low Back Pain on Sick Leave Duration
The purpose of this study is to determine whether an intensive 5 days long multidisciplinary program (including spa therapy, exercises and patients'education) is more effective regarding return to work than usual care in subacute…
- Trial name
- ITILO (NCT01648738)
- Testing
- Spa therapy, exercise and educational therapy, Usual care
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Low Back Pain
Unraveling Back Pain Chronicity: an EMG and EEG Study
This study aims at examining the influence of both threat of experimentally induced pain and clinical low back pain (LBP) on trunk motor control on the one hand and brain activity related to movement preparation on the other…
- Trial name
- NCT03705676
- Testing
- Rapid Arm Movements, Unpleasant stimulus, Vibrotactile stimulus
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Ghent
Mechanical Low Back Pain, Paraspinal Muscles
Effects of Back Muscles Endurance Training in Patients With Chronic Mechanical Low Back Pain
Low back pain is one the leading cause of disability and affecting many individuals. Chronic low back pain is associated with restriction in daily physical activities that ultimately leads to disuse atrophy of muscles.
- Conditions
- Mechanical Low Back Pain, Paraspinal Muscles, Muscle Stretching Exercises
- Trial name
- NCT05052840
- Testing
- Muscle endurance training (MET), Conventional Treatment
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Chronic Low-back Pain, Chronic Pain
HOnest Placebos With Explanations: Evaluating Open-Label Placebos for Chronic Pain
The goal of this clinical trial is to examine the effect of rationale condition when taking open-label placebos on pain by 1) comparing each rationale to the no rationale control condition and the no treatment control condition…
- Trial name
- HOPE (NCT06931158)
- Testing
- Standard Rationale, Mindfulness, Control Rationale
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Rhode Island Hospital
Osteoarthritis, Low Back Pain
An Efficacy and Safety Study of Fentanyl Transdermal Patch in Filipino Participants With Osteoarthritis and Chronic Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of fentanyl among Filipino participants with osteoarthritis (disorder which is seen mostly in older persons in which the joints become painful and stiff) and…
- Trial name
- NCT01795898
- Testing
- Fentanyl
- Where
- Philippines
- Volunteers
- 237 people
- Sponsor
- Janssen Pharmaceutica
Chronic Low Back Pain
Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain
The purpose of this study is to determine the efficacy and safety of EN3324 (axomadol) in subjects with moderate to severe chronic low back pain
- Trial name
- CLBP (NCT01043263)
- Testing
- EN3324 (axomadol)
- Where
- 59 sites in United States
- Volunteers
- 236 people
- Sponsor
- Grünenthal GmbH
Pain
Chronic Low Back Pain and Meditation
The purpose of this research study is to see if and how mindfulness meditation affects pain. Specifically, we are interested in assessing if mindfulness is associated with the release of naturally occurring opiates in the body…
- Trial name
- NCT04034004
- Testing
- Mindfulness, Naloxone, Saline
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- University of California, San Diego
Chronic Low Back Pain, Gait
Complexity & Distraction in LBP
Motor control, notably expressed through the complexity of the variability of the locomotor pattern, is disturbed at the central level by an apprehension of pain and movement, more than pain itself (or by biomechanical /…
- Conditions
- Chronic Low Back Pain, Gait, Motor Activity
- Trial name
- CoDiLoBP (NCT03633578)
- Testing
- walk test
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Low-back Pain
The Effect of Telerehabilitation in Patients With Chronic Low Back Pain
Telerehabilitation enables patients to easily adapt to home exercise programs and to be monitored remotely by their clinicians. The aim of this study is to investigate the effectiveness of the home exercise program, which is…
- Trial name
- NCT04567758
- Testing
- Telerehabilitation, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Marmara University
Acute Low Back Pain
Efficacy and Safety of Fixed-dose Combination of Etoricoxib/Tramadol vs Acetaminophen/Tramadol for Acute Low Back Pain
Phase IIIb, longitudinal, multicenter, randomized, open-label clinical trial to evaluate the efficacy and safety of the fixed-dose combination of etoricoxib 90 mg and tramadol 50 mg compared with fixed-dose therapy of…
- Trial name
- NCT04968158
- Testing
- Etoricoxib 90 mg / Tramadol 50 mg, Acetaminophen 325 mg / Tramadol 37.5 mg
- Where
- Mexico
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Chronic Pain
Efficacy of Therapy Using Monopolar Dielectric Radiofrequency Signals on the Symptoms of Myofascial Trigger Points in Patients With Chronic Nonspecific Low Back Pain.
A total of 74 people diagnosed with non-specific chronic low back pain of more than 3 months of evolution and who are not currently undergoing any type of treatment will be recruited, with ages between 35 and 65 years.
- Trial name
- NCT05471258
- Testing
- Experimental: monopolar dielectric diathermy
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad de Almeria
Chronic Lower Back Pain, Healthy Control Subjects
Psychobiological Mechanisms of Placebo and Nocebo Effects in the Treatment of Chronic Back Pain
Placebo and nocebo responses have mainly been studied in healthy humans for pharmacological rather than psychological interventions.
- Trial name
- NCT02157389
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Non-specific Low Back Pain (NSLBP)
Ultrasound-guided Biofeedback for Transversus Abdominus Re-education in Non-specific Low Back Pain Patients
As rehabilitative ultrasound imaging (RUSI) for monitoring and re-educating deep trunk muscles is becoming more and more popular in current musculoskeletal rehabilitation and research, the purpose of this pilot study was to…
- Trial name
- NCT05859425
- Testing
- Real-time rehabilitative ultrasound imaging (RUSI), Tactile feedback (control intervention)
- Where
- Greece
- Volunteers
- 23 people
- Sponsor
- University of Patras
Low Back Pain, Chronic Widespread Pain
13-year Follow-up of Women With Chronic Low Back Pain in Primary Care - a Prospective Longitudinal Cohort Study
Background: Low back pain (LBP) is among the main causes of long-term sickness absence and is associated with considerable costs for both the individual and society.
- Conditions
- Low Back Pain, Chronic Widespread Pain, Predictors, Pain
- Trial name
- NCT03974191
- Testing
- Change in function, activity, participation and other health related factors in CLBP and to identify predictors for pain, activity and work ability after 13 years.
- Where
- 3 sites in Sweden
- Volunteers
- 87 people
- Sponsor
- Vastra Gotaland Region
Chronic Low Back Pain, Back Pain
Predicting Analgesic Response to Acupuncture: A Practical Approach
In this placebo controlled, patient and assessor blinded clinical trial, the investigators will administer electroacupuncture vs sham electroacupuncture to patients suffering from chronic low back pain, and monitor their symptoms…
- Trial name
- NCT02890810
- Testing
- Real Acupuncture with Electrical Stimulation, Simulated Acupuncture with Electrical Stimulation
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Stanford University
Low Back Pain
Manipulation, Exercise, and Self-Care for Low Back Pain
The broad, long term objective of this interdisciplinary research is to identify effective therapies for low back pain sufferers and to increase our understanding of this important condition.
- Trial name
- NCT00269347
- Testing
- Chiropractic Spinal Manipulation, Exercise, Self-care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern Health Sciences University
Low Back Pain, Mechanical, Complementary Therapies
Craniosacral Therapy as a Self-help Strategy for Patients With Chronic Non-specific Back Pain
Craniosacral Therapy (CST) is a non-manipulative, very gentle manual treatment method. Although the mechanisms of action have not yet been investigated sufficiently, initial clinical trials support CST efficacy/effectiveness in…
- Conditions
- Low Back Pain, Mechanical, Complementary Therapies, Progressive Muscle Relaxation
- Trial name
- CRANIO4ME (NCT04199091)
- Testing
- Craniosacral Therapy (CST) self-help techniques, Progressive Muscle Relaxation (PMR)
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- Universität Duisburg-Essen
Discogenic Pain, Platelet-rich Plasma
Platelet-rich Plasma for Low Back Pain
This study aims to evaluate the effect of platelet-rich plasma (PRP) on discogenic low back pain by comparing the pre- and post-interventional outcomes in patients receiving intradiscal injection of autologous PRP.
- Trial name
- NCT03197415
- Testing
- Platelet-rich plasma
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Pei-Yuan Lee, MD
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