Clinical trials: Low Birth Weight Baby
Trophic Feeding, Very Low Birth Weight Baby
Effect of Oral Colostrum Applications Every 2 Hours and 4 Hours In Order to Achieve Trophic Feeding in Preterm Infants
The goal of this clinical trial is aims to evaluate the effects of applying colostrum orally every 4 and 2 hours in order to achieve trophic feeding in preterm infants.
- Conditions
- Trophic Feeding, Very Low Birth Weight Baby, Preterm
- Trial name
- NCT06379178
- Testing
- Oral colostrum application 2 hours, Oral colostrum application 4 hours
- Where
- Indonesia
- Volunteers
- 47 people
- Sponsor
- Gadjah Mada University
PDA, Low; Birthweight, Extremely (999 Grams or Less)
The Efficacy of Implementing a Treatment Algorithm in Managing Patent Ductus Arteriosus (PDA) in the Extremely Low Birth Weight Neonatal Population.
To evaluate whether utilizing a standardized patent ductus arteriosus (PDA) treatment algorithm in managing ELBW (extremely low birth weight) neonates ≤1000 grams (g) improves clinical outcomes and helps prevent undesirable side…
- Trial name
- NCT04379843
- Where
- 2 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Infant, Very Low Birth Weight
High Protein and High Energy Intakes and Physical Activity on Growth of Extremely Low Birth Weight Infants
The aim of this study is to evaluate the effect of increasing amino acid and energy intake during parenteral and enteral nutrition with and without the stimulation of the infant's physical activity, on growth of extremely low…
- Trial name
- NCT03374033
- Testing
- NUTR +, STIMUL +
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università Politecnica delle Marche
Low Birth-weight
KMC Implementation Research for Accelerating Scale-up in Oromia Region, Ethiopia
The main objective is to implement Kangaroo Mother Care (KMC) at selected facilities in Addis Ababa and Oromia Regions to achieve high effective coverage in the catchment population.
- Trial name
- KMC-Oromia (NCT03419416)
- Testing
- Kangaroo mother care (KMC)
- Where
- 2 sites in Ethiopia
- Volunteers
- 700 people
- Sponsor
- Addis Ababa University
Bronchopulmonary Dysplasia, Apnea of Prematurity
Early Versus Late Caffeine for ELBW Newborns
Caffeine is routinely used in the management of apnea of prematurity. Extremely low birth weight (ELBW) infants are at higher risk of mortality and various neonatal morbidities such as bronchopulmonary dysplasia (BPD) for which…
- Trial name
- NCT02524249
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Anemia, Low Birth Weight
Dietary Diversity is Associated With Maternal Anemia and Key Prenatal Outcomes in Ethiopia
Background: Maternal and child under-nutrition is the underlying cause of death for millions across the globe. Anemia during pregnancy is among the leading nutritional disorders with serious short and long term consequences to…
- Conditions
- Anemia, Low Birth Weight, Pre-Term Birth, Still Birth
- Trial name
- NCT02620943
- Where
- Ethiopia
- Volunteers
- 374 people
- Sponsor
- Dilla University
Iron Deficiency Anemia, Neurodevelopmental Abnormality
RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study
As a follow-up to the RAPIDIRON Trial (NCT05358509), this study will follow the previously randomized mothers as well as their offspring after birth to assess neurodevelopmental, hematologic, and health outcomes.
- Conditions
- Iron Deficiency Anemia, Neurodevelopmental Abnormality, Autism Spectrum Disorder
- Trial name
- RAPIDIRON-KIDS (NCT05504863)
- Testing
- Ferric carboxymaltose, Iron isomaltoside, Ferric Sulfate
- Where
- 3 sites in India
- Volunteers
- 538 people
- Sponsor
- Thomas Jefferson University
Bronchopulmonary Dysplasia, Respiratory Distress Syndrome
Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)
This multicenter clinical trial tested whether minimal ventilation decreases death or BPD. Infants with birth weight 501g to 1000g and mechanically ventilated before 12 hours were randomly assigned to minimal ventilation (partial…
- Conditions
- Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Infant, Newborn, Infant, Low Birth Weight
- Trial name
- SAVE (NCT00005777)
- Testing
- Minimal mechanical ventilation management, Routine mechanical ventilation management, Dexamethasone
- Where
- 13 sites in United States
- Volunteers
- 220 people
- Sponsor
- NICHD Neonatal Research Network
Invasive Candidiases
Efficacy of Prophylactic Fluconazole Therapy in Preterm and Very Low Birth Weight Neonates in Preventing Invasive Fungal Infection.
Invasive fungal infection is detecting candida species in blood, cerebrospinal fluid, or urine. Clinical signs of invasive candidiasis may include lethargy, temperature instability, feeding intolerance, apnea, hypotension…
- Trial name
- NCT05848492
- Testing
- Fluconazole, Saline
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia
Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants
Most preterm newborns are managed by phototherapy to reverse hyperbilirubinemia with the intent to prevent bilirubin neurotoxicity.
- Conditions
- Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia, Kernicterus, Infant, Premature
- Trial name
- NCT02691156
- Testing
- Bilirubin Binding Capacity, End-tidal Carbon Monoxide, Carboxyhemoglobin
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Stanford University
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia)
Analysis on the Health of Newborns in Three Hospitals, 2008-2024
The objective of this observational study is to analyze the factors associated with neonatal morbidity and mortality in three hospitals in Quito, Ecuador, from January 2008 to June 2024.
- Conditions
- Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia), Prematurity Complications, Neonatal Infections
- Trial name
- NCT06758622
- Where
- Ecuador
- Volunteers
- 40,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Gastric Tube Placement
Correct Gastric Tube Placement in Very Low Birth Weight Neonates
Gastric tube (GT) placement is a recurrent procedure in VLBW infants due to feeding impairment correlated with low birth weight.
- Trial name
- NCT04127773
- Testing
- oro gastric tube
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Low Birth Weight Infant
Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression
This is a prospective observational study to determine whether there is an association between the presence of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms and the development of chronic lung disease in…
- Trial name
- NCT00747240
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- University of Utah
Preterm Infant, Effect of Drugs
Zinc Supplementation In Very Low Birth Weight Infants-A Randomised Controlled Trial
Zinc (Zn) is a structural component of human body and is a crucial element for a wide variety of cascades that take place in almost all organ systems.
- Conditions
- Preterm Infant, Effect of Drugs, Zinc Deficiency Disease
- Trial name
- NCT05311540
- Testing
- Zinc Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Respiratory Distress Syndrome In Premature Infants
Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates
The purpose of this study is to determine the safety and effectiveness of the Babylog VN500 in high frequency oscillatory ventilation (HFOV) mode as a method for treating very low birth weight (VLBW) neonates requiring invasive…
- Trial name
- NCT02445040
- Testing
- Babylog VN500 in HFOV Mode
- Where
- 14 sites in United States
- Volunteers
- 225 people
- Sponsor
- Draeger Medical Systems, Inc.