Clinical trials: Low Bone Density
Bone Loss
Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss
This is a double-blind, randomized, placebo-controlled trial of zoledronic acid, 5mg, to be administered intravenously to people who have suffered an acute spinal cord fracture.
- Trial name
- NCT00844480
- Testing
- zoledronic acid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Thomas J. Schnitzer
Vitamin D Deficiency, Cystic Fibrosis
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF
Cystic fibrosis (CF) is an autosomal recessive disease caused by alterations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, characterized by multisystemic alterations, mainly in the lung, intestine…
- Conditions
- Vitamin D Deficiency, Cystic Fibrosis, Bone Density, Low, Inflammation Chronic
- Trial name
- NCT05276960
- Testing
- Cholecalciferol Pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Bone Loss
Maxillary Vascular Canal Thickness and Sinus Augmentation Bleeding
This study aims to evaluate the relationship between the maxillary intra-osseous vascular canal thickness as measured by volumetric tomography and the amount of intra-operative bleeding during open sinus floor augmentation.
- Trial name
- NCT05710497
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Menopause, Osteoporosis
Using Soy Estrogens to Prevent Bone Loss and Other Menopausal Symptoms
The purpose of this study is to determine if soy-derived phytoestrogens (naturally occurring compounds similar to estrogen) can prevent bone loss and other menopausal symptoms in women who have recently gone through menopause.
- Conditions
- Menopause, Osteoporosis, Osteopenia
- Trial name
- SPARE (NCT00076050)
- Testing
- Soy isoflavones
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Miami
Bronchiectasis Adult, Osteoporosis, Osteopenia
Role of NLRP3 Inflammasone and Hypoxia in the Severity of Osteoporosis in Patients With Bronchiectasis
The objectives of this research grant are to determine the association of hypoxia with the severity of osteoporosis in the patients with bronchiectasis and whether the mechanism of inflammation is triggered by inflammasones…
- Trial name
- NCT03467035
- Testing
- Inflammasone
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chun-Hua Wang, MD
Alveolar Process Atrophy
Evaluation of a Combined Ridge Expansion Technique With Simultaneous Dental Implant Placement
Patients with long span, narrow edentulous ridge in the posterior mandible underwent piezotomed ridge splitting and osseodensification with simultaneous implant placement.
- Trial name
- NCT05685576
- Testing
- Piezotomed ridge splitting and osseodensification
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Lydia Nabil
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Bone Loss, Inflammation
Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss
In patients that require a dental implant, does zirconia compared to titanium, or cad-cam acrylic abutments, provide less inflammation, marginal bone loss or infection during the osseointegration period ?
- Trial name
- NCT01961635
- Testing
- dental implants, Zirconia abutments, Titanium Abutments
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Vitamin D Deficiency, Osteoporosis
Study to Document the Phenomenon of Vitamin D Deficiency and Its Added Value in Patients with Low-energy Osteoporotic Hip Fracture, in Daily Practice in Greece.
Vitamin D, through its action on calcium metabolism, is essential for bone physiology. Vitamin D deficiency can affect muscle function and increase the risk of falls in the elderly, while severe deficiency is common in patients…
- Conditions
- Vitamin D Deficiency, Osteoporosis, Bone Loss, Age-Related, Fracture of Hip
- Trial name
- NCT06643650
- Testing
- CHOLECALCIFEROL ORAL.SOL 25000 IU/2,5ML
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- National and Kapodistrian University of Athens
Alveolar Bone Loss
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.
- Trial name
- NCT02709525
- Testing
- hyaluronic acid
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Osteoporosis, Osteopenia
Hormonal and Bone Turnover Marker Response to an Acute Bout of Resistance or Plyometric Exercise
We are interested in determining if there exist a short-term response in the serum markers and hormones that participate in the regulation of bone tissue formation and breakdown to a single, high-intensity exercise session of…
- Trial name
- NCT00572871
- Testing
- plyometric exercise, resistance exercise, No exercise
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Osteoporosis in Post-menopausal Women
Bone Health in Postmenopausal Women: The Effect of Exercise With or Without Medication for Osteoporosis
Osteoporosis is a systemic bone disorder characterised by a reduced bone mass and structural deterioration, increasing the risk of fragility fractures, particularly in women post-menopause.
- Trial name
- BEAT-OP (NCT07267325)
- Testing
- EXERCISE TRAINING, Antiresorptive medication (routine clinical care)
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Alveolar Bone Loss
Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
- Trial name
- NCT05336149
- Testing
- Alveolar ridge preservation using whole-tooth dentin graft, Alveolar ridge preservation using particulate dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis, Periodontal Bone Loss
Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.
The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.
- Conditions
- Chronic Periodontitis, Periodontal Bone Loss, Resistance Bacterial
- Trial name
- NCT03863249
- Testing
- SCALE AND ROOT PLANING, ADJUNTIVE ANTIBIOTICS, MICROBIAL SAMPLING
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Valencia
Alveolar Bone Loss
Lamina Soft With Different Collagen Based Materials in Bone Regeneration
This prospective controlled clinical pilot study will compare the effectiveness of two different grafting strategies for horizontal bone regeneration in healed post-extraction sites with buccal bone deficiency, using a…
- Trial name
- NCT07572643
- Testing
- Guided Bone Regeneration with Implant Placement, Collagenated Xenogeneic Bone Graft, Hydroxyapatite Xenograft with Autologous Bone
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Nicola Alberto Valente, DDS, MS, PhD
Osteopenia or Osteoporosis
Pulsed Electromagnetic Field Versus Pulsed High Intensity Laser in the of Osteoprosis
Osteoporosis is the most prevalent metabolic bone disease. Although osteoporosis is widely considered to be much more prevalent in women approximately 39% of new osteoporotic fractures estimated to have occurred Worldwide in 2000…
- Trial name
- NCT05029440
- Testing
- Pulsed Electromagnetic Field, Exercise Program, Pulsed High Laser Therapy
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Umm Al-Qura University
Vertical Alveolar Bone Loss
Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects
Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix…
- Trial name
- NCT06639555
- Testing
- PRP( platelet rich plasma), EMD (Enamel Matrix Derivative), Guided Tissue Regeneration (barrier membrane)
- Where
- Bulgaria
- Volunteers
- 48 people
- Sponsor
- Tsvetalina Gerova-Vatsova
Vertical Alveolar Bone Loss
Clinical Evaluation of RTX Locator Attachments for Implant-supported Mandibular Complete Overdenture
This study was conducted to clinically and radiographically evaluate locator RTx attachments for two implant-supported mandibular overdenture using two loading protocols
- Trial name
- NCT05290376
- Testing
- surgical placement of long dental implants, overdenture supported by RTX attachment system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bone Loss in Jaw
Bone Level Evaluation Around Implants in All on Four Hybrid Restorations With Different Connections (Radiographic Evaluation)
this research aims to compare between using multiunit abutments and OT Equator abutments for constructing implant supported fixed mandibular prosthesis regarding the marginal bone height alteration around the implants through…
- Trial name
- NCT07333235
- Testing
- different types of abutments (multiunit abutments OR OT EQUATOR abutments) will be screwed to the four implants to support the prosthesis
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Ain Shams University