Clinical trials: Low Cost
Pre-eclampsia
Assessment of a Syringe Pump to Pre-eclamptic Women in a Low-resource Hospital
Pre-eclampsia and eclampsia cause 50,000 deaths annually. While MgSO4 is a widely accepted and relatively inexpensive treatment for these conditions, barriers to delivery via IV injection in low-resource settings pose a large…
- Trial name
- NCT02296931
- Testing
- Saline, Magnesium Sulfate
- Where
- Malawi
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- William Marsh Rice University
COVID-19
Low-cost Sensor System for COVID-19 Patient Monitoring: Validation of BRAEBON Vital Signs Monitor (VTS)
The BRAEBON VTS is a low-cost, portable device that is being developed to take continuous and real-time vital sign measurements of COVID-19 patients, both in the hospital and home setting.
- Trial name
- NCT05029011
- Testing
- BRAEBON VTS
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- Helen S. Driver, PhD
Airway Management
Use of a Low-cost Video Laryngoscope on Manikin
Videolaryngoscopy has become essential in airway management, providing improved glottis visualization and reducing intubation attempts.
- Trial name
- NCT06176677
- Testing
- Videolaryngoscope, Boroscope
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Azienda USL Toscana Nord Ovest
Bacterial Infections
Use of Low-cost Molecular Diagnostic Techniques as a New Surveillance Model for Diseases Preventable by Vaccinations.
Vaccine-preventable disease (VPD) surveillance should be a priority throughout the world. In Italy, however, there is limited attention to the epidemiology of VPDs, with the consequence that their incidence is largely…
- Trial name
- NCT06322277
- Testing
- Analysis of biological sample
- Where
- 4 sites in Italy
- Volunteers
- 1 people
- Sponsor
- Meyer Children's Hospital IRCCS
Spinal Cord Injuries
Validity and Reliability of a Low-cost Chair Dynamometer
In part 1 of the study, fourteen able-bodied individuals will undergo maximal, voluntary contraction (MVC) test of the lower limbs in two dynamometers.
- Trial name
- NCT04291924
- Testing
- Dynamometry
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Spinal Cord Injury Centre of Western Denmark
Spinal Deformity
Cost Effectiveness of Nonoperative Management for Adult Spinal Deformity
Quantify the efficacy and cost of nonoperative treatment modalities used for adult spinal deformity.
- Trial name
- HEO (NCT01880164)
- Where
- 10 sites in United States
- Volunteers
- 21 people
- Sponsor
- Shay Bess
Randomized Controlled Trial
Cost-utility and Physiological Effects of LDN in Patients With Fibromyalgia
Background: Low-dose naltrexone (LDN) may be useful in managing the pathologies that alter inflammatory markers, such as Crohn's disease or fibromyalgia (FM).
- Trial name
- INNOVA (NCT04739995)
- Testing
- Low-dose naltrexone
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Fundació Sant Joan de Déu
Head and Neck Cancer, Oral Cancer
Low-Cost, Portable Flexible Nasopharyngoscope in Head & Neck Cancers in Low Resource Settings - Optimization Phase
This study aims to develop and evaluate a low-cost, portable, flexible nasopharyngeal scope (FNS) used to assess head and neck cancers (HNC) in low resource settings.
- Trial name
- NCT04905134
- Testing
- Nasopharyngoscope
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Oral Cancer, Oral Cavity Cancer
Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions
The primary goal of this study is to see if photodynamic therapy (PDT) is effective for treatment of lesions in the oral cavity which have high risk of becoming oral cancer.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Leukoplakia, Oral Lichen Planus
- Trial name
- NCT06876038
- Testing
- 5-Amino Levulinic Acid
- Where
- 2 sites in India
- Volunteers
- 65 people
- Sponsor
- University of Massachusetts, Boston
Cerebral Palsy
Virtual Reality in Children With Cerebral Palsy
OBJECTIVE: To investigate whether VR videogames plus conventional therapy improves motor control compared with conventional therapy in children with cerebral palsy (CP). METHODS: Thirty participants with CP were included.
- Trial name
- NCT02500433
- Testing
- Device: Kinect-Xbox 360TM, Conventional therapy
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Diarrhoea;Infectious;Presumed, Diarrhea, Infantile
Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa
This project is a community-based randomized controlled trial designed to test the effectiveness of two point-of-use water treatment technologies to improve clean drinking water access, reduce enteropathogen burden, and improve…
- Conditions
- Diarrhoea;Infectious;Presumed, Diarrhea, Infantile, Diarrhea Tropical, Environmental Exposure
- Trial name
- NCT03012048
- Testing
- Silver-impregnated ceramic tablet, Silver-impregnated ceramic water filter, Safe-storage water container
- Where
- South Africa
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Diabetes Mellitus, Affective Disorders
Depression and Diabetes Control Trial
This randomised controlled trial evaluates a cognitive-behavioural intervention for diabetes patients with suboptimal glycaemic control and comorbid depressive symptoms and/or diabetes distress.
- Conditions
- Diabetes Mellitus, Affective Disorders, Depression, Depressive Symptoms
- Trial name
- DDCT (NCT02675257)
- Testing
- Diabetes-related affective problems analysis, Goal setting towards improvement of glycaemic control, Diabetes-specific problem-solving therapy
- Where
- 2 sites in Germany
- Volunteers
- 213 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Hearing Loss
Evaluation of a New mHealth Tympanometer
Children in rural and underserved communities experience a disproportionately high burden of infection-related hearing loss, which is often preventable with timely identification and follow-up care.
- Trial name
- NCT05666505
- Testing
- Prototype mHealth tympanometer, Standard of care commercial tympanometer
- Volunteers
- 39 people
- Sponsor
- University of Arkansas
Recurrent Low Back Pain
Yoga vs. Education for Veterans With Chronic Low Back Pain
Chronic low back pain (cLBP) is the most common pain condition in the military, causing substantial physical and psychological suffering, reduction in force readiness, and high economic cost.
- Trial name
- NCT02224183
- Testing
- Education, Yoga
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Medical Center
Diarrhea, Communicable Diseases
Automatic Chlorination and Child Health in Urban Bangladesh
Municipal water networks within industrialized countries typically rely on centralized treatment to manage piped water quality. Optimal water quality at the tap, however, requires well-maintained piped distribution networks, and…
- Trial name
- NCT02606981
- Testing
- Water chlorination by the Flogenic, Active control, vitamin C dosing into water
- Where
- Bangladesh
- Volunteers
- 1,549 people, healthy volunteers welcome
- Sponsor
- Stanford University
DNA Probes, E6 Protein
Low-Cost Molecular Cervical Cancer Screening Study
Background: Low-cost molecular human papillomavirus (HPV) testing may offer a more robust alternative to Pap smears and visual inspection for cervical cancer screening of underserved women.
- Conditions
- DNA Probes, E6 Protein, Uterine Cervical Neoplasms, HPV
- Trial name
- NCT01231945
- Where
- 2 sites in United States, China
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Facilatated STAIR Coach
Use of Facilitated STAIR Coach in Kenya
The specific aim of this project is to examine the feasibility of using a low cost, low intensity, mobile app-based intervention teaching emotion regulation and interpersonal skills to improve general well-being for those with…
- Trial name
- NCT06476457
- Testing
- STAIR Coach
- Volunteers
- 10 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Pectus Deformity
X-ray-free Protocol for Pectus Deformities Based on Magnetic Resonance 1 Imaging and a Low-cost Portable Three-dimensional Scanning Device
Pectus excavatum (PE) and pectus carinatum (PC) are the most frequent chest wall deformities in humans. They are usually clinically recognized in early childhood or adolescence, with aggravation during the pubertal growth spurt.
- Trial name
- NCT04885387
- Testing
- chest CT, Magnetic Resonance Imaging and a low-cost portable three-dimensional scanning device
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Limoges
Depression
Learning Through Play (LTP) Plus Intervention for Depressed Fathers (LTP Plus Dads)
The aim of the study is to evaluate the clinical and cost effectiveness of culturally adapted group parenting intervention delivered by non-specialists and community health workers for depressed fathers.
- Trial name
- LTP+Dads (NCT03564847)
- Testing
- LTP Plus
- Where
- 2 sites in Pakistan
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Hepatitis C, Chronic, Substance Use Disorders
Linkage to Care for Persons With Hep C Infection
Hepatitis C Virus (HCV) infection is an ongoing challenge in the United States, with an estimated 2.4 million individuals living with HCV in 2016.
- Trial name
- NCT05397067
- Testing
- Peer specialist (PS), Incentives, telehealth visits
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic