Clinical trials: Low Cost
Cervical Cancer Screening
Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (Phase 2)
In high-income countries, prevention strategies have led to declines in cervical cancer rates by more than 75% in high-income countries.
- Trial name
- SCALE AIM 2 (NCT07538050)
- Testing
- Same day screen and treat
- Where
- El Salvador
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Open Access, Medical Devices
Validation of a High-Quality Low-Cost Open-Source Electrocardiograph
The high price of electrocardiograph (ECG) devices - with most hospital-grade devices costing thousands of dollars - is one of the barriers to access of this vital technology.
- Conditions
- Open Access, Medical Devices, Low Cost, Electrocardiograph
- Trial name
- NCT04209062
- Testing
- Medical device validation
- Where
- Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Low-Value Care, Costs and Cost Analysis
Optimization of Low-Value Medical Testing Practices in Hospitalized Patients in Argentina
Overuse of laboratory testing in hospitalized patients is a common form of low-value care and may contribute to patient discomfort, unnecessary downstream testing, inefficient use of healthcare resources, and increased costs.
- Conditions
- Low-Value Care, Costs and Cost Analysis, Implementation Science, Public Health
- Trial name
- OPTIMIZAR (NCT07629219)
- Testing
- OPTIMIZAR Multicomponent Diagnostic Stewardship Bundle
- Where
- 8 sites in Argentina
- Volunteers
- 600 people
- Sponsor
- Hospital Italiano de Buenos Aires
Colorectal Cancer, Colonic Polyp
Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of Life
Adequate bowel preparation for colonoscopy is paramount for optimal diagnostic accuracy and safety. However, the need for high volumes to clean the colon often makes it difficult for patients to adhere to.
- Trial name
- RESULT (NCT05242562)
- Testing
- Plenvu, Moviprep
- Where
- Netherlands
- Volunteers
- 509 people
- Sponsor
- Radboud University Medical Center
Gait Analysis
Reliability of a Gait Analysis System
Gait disturbances can be observed in all age groups, and may be due to different conditions, such as advanced age, stroke, head trauma, spinal cord injury, cerebral palsy, myelomeningocele, among others.
- Trial name
- NCT05538221
- Testing
- SILEMA
- Where
- Argentina
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centro Integral de Neurologia y Especialidades Afines, Argentina
Safety Issues
Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode
Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the…
- Trial name
- NCT03465475
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Inonu University
HIV-1-infection
Kenya HIV Self-Testing in PrEP Delivery
In a three-arm, randomized trial, the investigators will test the use of HIV-1 self-testing to decrease the frequency and burden of clinic visits for PrEP while resulting in equivalent PrEP adherence and HIV testing.
- Trial name
- NCT03593629
- Testing
- 6-month PrEP + blood-based HIV self-test, 6-month PrEP + oral fluid HIV self-test
- Where
- Kenya
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University of Washington
Low Back Pain
The Costs and Effectiveness of Cognitive Functional Therapy for People with Persistent Low Back Pain in Coventry.
Previous studies have shown Cognitive Functional Therapy (CFT) results in sustained clinically important improvements compared to a variety of interventions for persistent low back pain (LBP).
- Trial name
- NCT06161753
- Testing
- Cognitive Functional Therapy
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Low Back Pain
Low-Cost Tool for Compliance and Treatment-Tracking of Low Back Pain Patients
The purpose of the study is to develop, design and implement an easy-to-use, cloud-enabled software for patients with low back pain and evaluate the effect of the system on compliance and quality of life.
- Trial name
- NCT03478007
- Testing
- Intervention Technology, Intervention Technology Plus Coaching
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Mayo Clinic
Physical Activity
Peer Empowerment Program for Physical Activity in Low Income and Minority Seniors
Older adults are the least active population group in the US. Yet, research has shown that an increase in physical activity (PA) can have immediate and profound effects on cardiovascular health.
- Trial name
- PEP4PA (NCT02405325)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Colon Polyps, Colonic Dysplasia
Evaluation of a Low-Cost High Resolution Microendoscope for the Detection of Lower Gastrointestinal Neoplasia
The overall objective of this study is to obtain data to evaluate whether high-resolution imaging of the colon can assist clinicians in detecting dysplastic (precancerous) and neoplastic areas.
- Conditions
- Colon Polyps, Colonic Dysplasia, Anal Dysplasia
- Trial name
- NCT01384240
- Testing
- Proflavine Hemisulfate
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Anandasabapathy, Sharmila, M.D.
Low Flow Anesthesia, Sevoflurane Anesthesia
Ultra-Low-Flow Anesthesia and Carbon Footprint
This is a prospective, randomized controlled clinical trial evaluating the effects of ultra-low fresh gas flow (0.5 L/min) versus normal fresh gas flow (2.0 L/min) sevoflurane anesthesia in adult patients undergoing on-pump…
- Conditions
- Low Flow Anesthesia, Sevoflurane Anesthesia, Cardiac Surgery
- Trial name
- NCT07313969
- Testing
- ultra low flow anesthesia, normal flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Usability Satisfaction
Comparison of Usability Satisfaction of the Newly Developed Low-cost Thermoplastic Splint and Commercial Thermoplastic Splint
Low-temperature thermoplastic has been commonly used in the fabrication of hand splints. However, its high cost and limited accessibility pose challenges for both clinicians and clients.
- Trial name
- NCT06843746
- Testing
- Commercial thermoplastic, Newly developed low-cost thermoplastic
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Mahidol University
Pulmonary Emphysema
Low Cost Biological Lung Volume Reduction Therapy for Advanced Emphysema
The clinical utility of bronchoscopic methods for achieving lung volume reduction has been evaluated in patients with advanced emphysema because these procedures are uniformly safer than surgical volume reduction.
- Trial name
- BLVR (NCT02107209)
- Testing
- Bronchoscopic Lung volume reduction
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Mansoura University
Diabetes Mellitus
Inter-Device Concordance of Plantar Thermal Asymmetry Measurement (HIK-DM-2026)
This cross-sectional observational study measures the inter-device concordance between two infrared thermographic cameras, a low-cost model (HIKMICRO Mini2 V2) and a high-resolution model (HIKMICRO M60), when measuring plantar…
- Trial name
- NCT07463456
- Testing
- HIKMICRO® Mini2 V2, HIKMICRO® M60
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Eduardo Luis Martín Javier
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Walking Mesh
Smart Sock for Monitoring Walking and Supporting Physical Activity in Older Adults: A Family-Supported Feasibility Study
The goal of this randomized feasibility clinical trial is to learn whether a low-cost smart sock and mobile application can be used safely, reliably, and comfortably to support gradual walking activity in adults aged 60 years and…
- Trial name
- NCT07902102
- Testing
- Low-Cost Smart Sock and Older-Adult Mobile Application, Standard Individual Walking Plan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Health Care Utilization, Health Care Seeking Behavior
Connecting Low-Income Adults to Primary Care After Inpatient Discharge
Healthcare systems and insurers have tried to reduce costs by improving the care and coordination provided to patients with high healthcare spending.
- Trial name
- NCT05567224
- Testing
- Access to primary care services
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Vanderbilt University Medical Center
Meningitis, Pediatric Infectious Diseases
Paediatric Infections Point-Of-Care
This study aims to identify the aetiology of childhood meningitis in Southwestern Uganda and develop and evaluate new methods for point-of-care diagnosis of childhood meningitis in a low-income setting.
- Trial name
- PI-POC (NCT03900091)
- Testing
- Multiplex PCR assay for meningitis, Multiplex vertical flow microarrray assay for meningitis, Profiling of blood proteins by multi-analyte Profiling technology
- Where
- 2 sites in Uganda
- Volunteers
- 351 people
- Sponsor
- Karolinska Institutet
Lower Back Pain Chronic, Lumbar Degenerative Disease
Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain
Background Degenerative disc disease (DDD) is the leading cause of lower back pain and disability, which prevalence increasing with age. When conservative treatment fails, surgical methods of spinal fusion are employed.
- Conditions
- Lower Back Pain Chronic, Lumbar Degenerative Disease, Lumbar Disc Degeneration, Degenerative Disc Disease(DDD)
- Trial name
- MID-MIS (NCT07127380)
- Testing
- Midline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Copernicus Memorial Hospital