Clinical trials: Low Cost
Infant Development
A Community Based Implementation of a Toolkit and Parenting Program for Improving Brain Development in Newborns
The investigators propose to develop and test the efficacy of a low cost evidence based toolkit aimed at improving brain development among newborns a rural setting of Pakistan.
- Trial name
- NCT02290756
- Testing
- Parenting Program, Low cost evidence based toolkit
- Where
- Pakistan
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Oral Cancer, Oral Cavity Cancer
Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions
The primary goal of this study is to see if photodynamic therapy (PDT) is effective for treatment of lesions in the oral cavity which have high risk of becoming oral cancer.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Leukoplakia, Oral Lichen Planus
- Trial name
- NCT06876038
- Testing
- 5-Amino Levulinic Acid
- Where
- 2 sites in India
- Volunteers
- 65 people
- Sponsor
- University of Massachusetts, Boston
Anxiety, Obsessive Compulsive Disorder
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. Investigators aim to enhance this therapy with the use of virtual reality exposures and to make therapy more…
- Trial name
- NCT02713516
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cerebral Palsy, Acquired Brain Injury
Virtual Reality and Active Video Games to Improve Balance in Children With Brain Injury
The purpose of this pilot feasibility study is to assess the feasibility of using the Playstation Xbox 360 and Rutgers V-step via a Kinect Sensor with active video game software as a part of a physical therapy intervention to…
- Trial name
- NCT03386968
- Testing
- Active video gaming, Usual care physical therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Blythedale Children's Hospital
General Anaesthesia
Low Flow Anaesthesia, is There a Difference Between 2 Modern Anaesthetic Machines Using Different Gas Reservoir
To study the Flow-I breathing circle during low flow general anaesthesia, whether this non-below system has advantages reduced time to reach Et 1MAC (minimal alveolar concentration) and lower consumption of inhaled agent
- Trial name
- LF (NCT02013869)
- Testing
- Flow-I, a modern anaesthetic machine without a bag/below/gas reservoir for compression of insufflation gas, Asys, a anaesthetic machine with a bag/bellow for compression of gas to be insufflated
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Jan Jakobsson
Refractive Errors
Investigation of the Accuracy of a Low-cost, Portable, Autorefractor to Provide Well-tolerated Eyeglass Prescriptions
At the Aravind Eye Hospital (AEH) in Madurai, India, patients ages 18-40 receiving treatment for refractive error who choose to enroll in the study will be evaluated using subjective refraction and objective refraction, by way of…
- Trial name
- NCT03615612
- Testing
- QuickSee refractive error assessment + glasses
- Where
- India
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cerebral Palsy
Virtual Reality in Children With Cerebral Palsy
OBJECTIVE: To investigate whether VR videogames plus conventional therapy improves motor control compared with conventional therapy in children with cerebral palsy (CP). METHODS: Thirty participants with CP were included.
- Trial name
- NCT02500433
- Testing
- Device: Kinect-Xbox 360TM, Conventional therapy
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Low Back Pain
Effectiveness of a Short, Intensive and Standardised Spa Therapy for Low Back Pain on Sick Leave Duration
The purpose of this study is to determine whether an intensive 5 days long multidisciplinary program (including spa therapy, exercises and patients'education) is more effective regarding return to work than usual care in subacute…
- Trial name
- ITILO (NCT01648738)
- Testing
- Spa therapy, exercise and educational therapy, Usual care
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure, Ventricular Dysfunction, Left
ECG Low Ejection Fraction Detection and Guiding in AI Navigated Treatment Era
Asymptomatic left ventricular systolic dysfunction (ALVSD), identified as a key component of stage B heart failure (HF) by AHA/ACC guidelines, is a common precursor to clinically overt HF.
- Conditions
- Heart Failure, Ventricular Dysfunction, Left, Artificial Intelligence, Early Diagnosis
- Trial name
- ELEGANT (NCT06968533)
- Testing
- AI-ECG guided diagnosis
- Where
- Taiwan
- Volunteers
- 13,350 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
RheumatoId Arthritis
The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study
Comparing the cost-effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rheumatoid arthritis: The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study (GLORIA)
- Trial name
- Gloria (NCT02585258)
- Testing
- Prednisolone
- Where
- 28 sites in Germany, Hungary and 5 more
- Volunteers
- 451 people
- Sponsor
- Amsterdam UMC, location VUmc
Premature, Respiratory Distress Syndrome in Premature Infant
Novel Low Cost Bubble CPAP as an Alternative Respiratory Support in Low Resource Setting
This is a single-blind randomized controlled trial done in a Level III neonatal intensive care unit. Preterm newborns with RDS were randomized to receive oxygen therapy through bubble CPAP vs ventilator-derived CPAP.
- Trial name
- NCT06082674
- Testing
- Vayu bCPAP, Mechanical Ventilator Driven CPAP
- Where
- Philippines
- Volunteers
- 70 people
- Sponsor
- Ilocos Training and Regional Medical Center
Low-flow Anesthesia
High vs. Low Flow Sevoflurane Anesthesia in Pediatric Laparoscopic Surgery: Recovery, Hemodynamics, and Cost Comparison
The primary objective of our study is to compare the effects of different flow rates of the routinely used inhalation agent, sevoflurane, on postoperative recovery times in pediatric patients undergoing elective laparoscopic…
- Trial name
- NCT06676969
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Rectal Neoplasms, Colostomy Stoma
Pseudo Continent Perineal Colostomy vs Permanent Left Iliac Colostomy After Abdominoperineal Resection for Ultra Low Rectal Adenocarcinoma
Aim of this study is to compare the cost-effectiveness and the quality of life in the 6 months following the surgery of a pseudo continent perineal colostomy (PCPC) and a permanent left iliac colostomy (PLIC) following an…
- Conditions
- Rectal Neoplasms, Colostomy Stoma, Quality of Life
- Trial name
- NCT04141566
- Testing
- Perineal pseudocontinent colostomy, Permanent left iliac colostomy
- Where
- Morocco
- Volunteers
- 35 people
- Sponsor
- Moroccan Society of Surgery
Cognitive Dysfunction, Dementia
ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings
Our study objective is to widely implement and evaluate a user-centered, scalable, electronic health record (EHR)-linked strategy for the routine detection of cognitive decline among diverse primary care settings.
- Trial name
- NCT04852601
- Testing
- ToolboxDetect
- Where
- United States
- Volunteers
- 35,403 people
- Sponsor
- Northwestern University
Postpartum Hemorrhage
Kenya: The Barriers and Facilitators of Scaling up the Ellavi UBT for Postpartum Hemorrhage
The purpose of this implementation research study is to generate evidence that informs the successful uptake and adoption of the Ellavi Uterine Balloon Tamponade (UBT) within Kenyan postpartum hemorrhage (PPH) management…
- Trial name
- NCT04502173
- Testing
- Ellavi UBT
- Where
- Kenya
- Volunteers
- 200 people
- Sponsor
- PATH
Airway Management
Use of a Low-cost Video Laryngoscope on Manikin
Videolaryngoscopy has become essential in airway management, providing improved glottis visualization and reducing intubation attempts.
- Trial name
- NCT06176677
- Testing
- Videolaryngoscope, Boroscope
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Azienda USL Toscana Nord Ovest
Breast Cancer, Tear
Tear Based Sample Collection Breast Cancer Detection
This study aims to collect tear samples from 50 women who have been recently diagnosed with breast cancer.
- Conditions
- Breast Cancer, Tear, Breast Cancer Female
- Trial name
- NCT04974567
- Testing
- Schirmer Strip
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Namida Lab
Pneumococcal Infections, Immunization Programs
Randomized Controlled Trial Of Text Messages To Increase Pneumococcal Vaccination In Adults In Chile.
The goal of this randomized controlled trial is to learn if text message reminders sent through WhatsApp increase pneumococcal vaccination coverage in adults turning 65 years old in Chile.
- Conditions
- Pneumococcal Infections, Immunization Programs, Vaccination Coverage, Text Messaging (Intervention)
- Trial name
- PNEUMO-SMS (NCT07659470)
- Testing
- WhatsApp text message reminder for pneumococcal vaccination
- Where
- Chile
- Volunteers
- 40,753 people, healthy volunteers welcome
- Sponsor
- Pablo Tomás Valenzuela García
Anxiety
Clinical and Cost Effectiveness of Alpha-Stim AID CES
This is a single-centre research study in patients seen within an NHS Improving Access to Psychological Interventions (IAPT) service with suspected generalised anxiety disorder (GAD).
- Trial name
- NCT02901080
- Testing
- Alpha Stim AID cranial electrotherapy stimulation, Pregnancy test, Anxiety questionnaire
- Where
- United Kingdom
- Volunteers
- 161 people
- Sponsor
- Electromedical Products International, Inc.
Acute Chest Pain
Coronary CT Angiography in Acute Chest Pain is a Cost Effective Risk Stratification Strategy
This study will evaluate the impact of adding coronary computed tomographic angiography (CTA) on health care costs for diagnosing patients with acute chest pain.
- Trial name
- NCT00825435
- Testing
- Coronary CT Angiogram
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center