Clinical trials: Low Flow Anesthesia
General Anaesthesia
Low Flow Anaesthesia, is There a Difference Between 2 Modern Anaesthetic Machines Using Different Gas Reservoir
To study the Flow-I breathing circle during low flow general anaesthesia, whether this non-below system has advantages reduced time to reach Et 1MAC (minimal alveolar concentration) and lower consumption of inhaled agent
- Trial name
- LF (NCT02013869)
- Testing
- Flow-I, a modern anaesthetic machine without a bag/below/gas reservoir for compression of insufflation gas, Asys, a anaesthetic machine with a bag/bellow for compression of gas to be insufflated
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Jan Jakobsson
Low Flow Anesthesia, Sevoflurane Anesthesia
Ultra-Low-Flow Anesthesia and Carbon Footprint
This is a prospective, randomized controlled clinical trial evaluating the effects of ultra-low fresh gas flow (0.5 L/min) versus normal fresh gas flow (2.0 L/min) sevoflurane anesthesia in adult patients undergoing on-pump…
- Conditions
- Low Flow Anesthesia, Sevoflurane Anesthesia, Cardiac Surgery
- Trial name
- NCT07313969
- Testing
- ultra low flow anesthesia, normal flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Laparoscopic Cholecystectomy, Postoperative Sore Throat
Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
Several studies have demonstrated that inhalational anesthetic agents such as desflurane and sevoflurane may cause varying degrees of postoperative sore throat, hoarseness, and cough in orotracheally intubated patients.
- Trial name
- NCT07440758
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kayseri City Hospital
Atelectasis, Nasal Septal Deviation
Fresh Gas Flow Rate and Perioperative Lung Aeration Assessed by Lung Ultrasound in Septoplasty
This prospective, single-center observational cohort study evaluated the association between fresh gas flow rate during inhalational anesthesia and perioperative changes in lung aeration in adults undergoing elective surgery for…
- Trial name
- NCT07758517
- Testing
- Fresh Gas Flow Rate of 1 L/min, Fresh Gas Flow Rate of 3 L/min
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hemodynamics Instability, Arrhythmias Cardiac
Low and Moderete Flow Anaesthesia on Haemodynamics
The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.
- Conditions
- Hemodynamics Instability, Arrhythmias Cardiac, Cerebral Oxygenation
- Trial name
- NCT06871371
- Testing
- Sevoflurane (Volatile Anesthetic), low- medium flow anesthetic machine
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Umraniye Education and Research Hospital
Oxidative Stress, Anesthesia
Comparison of Total Oxidant and Total Antioxidant Capacities in Low-Flow and High-Flow General Anesthesia
The goal of this observational study is to determine whether low-flow anesthesia has a positive contribution to the total oxidant/antioxidant balance.
- Trial name
- NCT05590312
- Testing
- general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Duzce University
Laparoscopic Cholecystectomy, Anesthesia, General
LMA Protector vs I-Gel in Low-Flow Anesthesia for Laparoscopic Cholecystectomy
This prospective randomized study aims to compare two second-generation supraglottic airway devices (SGAs), the I-Gel and the laryngeal mask airway (LMA) Protector, in patients undergoing laparoscopic cholecystectomy under…
- Trial name
- NCT07707440
- Testing
- I-Gel supraglottic airway, LMA Protector supraglottic airway
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Safety Issues
Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode
Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the…
- Trial name
- NCT03465475
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Inonu University
Anesthesia
Different Low-flow Sevoflurane Anesthesia Techniques
After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane…
- Trial name
- NCT04743193
- Testing
- 2.5 %sevoflurane, 8% sevoflurane low flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Low-flow Anesthesia
High vs. Low Flow Sevoflurane Anesthesia in Pediatric Laparoscopic Surgery: Recovery, Hemodynamics, and Cost Comparison
The primary objective of our study is to compare the effects of different flow rates of the routinely used inhalation agent, sevoflurane, on postoperative recovery times in pediatric patients undergoing elective laparoscopic…
- Trial name
- NCT06676969
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Anesthesia
Low Fresh Gas Flow in Prone Position
Low flow anesthesia in the prone position was safe in terms of systemic hemodynamics and did not reduce cerebral oxygenation compared to normal flow.
- Trial name
- NCT05462327
- Testing
- Low Fresh Gas Flow in Prone Position, Normal Fresh Gas Flow in Prone Position
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Morbid Obesity, Anesthesia Awareness
Comparison of Low Versus Normal Flow Anesthesia on Cerebral Oxygenation and Bispectral Index in Morbidly Obese Patients
Obesity is a chronic disease that affects quality and duration of life negatively. It's not clearly known the effects of low flow anesthesia on cerebral oxygenation with high-risk morbidly obese patients.
- Conditions
- Morbid Obesity, Anesthesia Awareness, Anesthesia Complication
- Trial name
- CerOxygen (NCT03438734)
- Testing
- Regional cerebral oxygen saturation, Bispectral Index (BIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Inonu University
Low-flow Anesthesia
Effects of Minimal and Metabolic Flow Sevoflurane Anesthesia in Gynecological Surgery Patients
The aim of this study is to observe the effects of minimal and metabolically required basal anesthetic gas flow rates delivered by the anesthesia workstation under general anesthesia on body temperature, blood pressure, and heart…
- Trial name
- NCT07465146
- Testing
- Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Baskent University
Male Urogenital Diseases, Female Urogenital Diseases
Comparison of Gas Consumption From Two Different Anesthesia Machines
Low flow anesthesia (LFA) is used less than desirable, partly because one has considered that there might be danger of underdosing of anesthesia gas and thus risk of awareness under anesthesia.LFA has several advantages such as…
- Trial name
- NCT02774031
- Testing
- Aisys with Et control, Aisys conventional, Flow-i with ACG
- Where
- Norway
- Volunteers
- 147 people
- Sponsor
- St. Olavs Hospital
Low Flow Anesthesia
Changes in Quality of Recovery With Low-Flow Anesthesia (QoRinLowflow)
Postoperative recovery quality is as important as patient satisfaction and clinical results in terms of a fast and high-quality surgical process.
- Trial name
- (QoRLowflow (NCT05773417)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Acibadem University
Child, Only, Inhalation; Vapor
Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric
To investigate the effects of non-invasive cerebral and peripheral NIRS monitoring and low and high flow sevoflurane anaesthesia on cerebral and peripheral NIRS in paediatric patients.
- Conditions
- Child, Only, Inhalation; Vapor, Anesthesia, Cerebral Oxygenation
- Trial name
- NCT06320743
- Testing
- NIRS ,Ventilation parameters, Oxygen concentration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
Perfusion Index, Low-Flow Anesthesia
Perfusion Index in Pediatric Low-Flow Anesthesia
This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia.
- Conditions
- Perfusion Index, Low-Flow Anesthesia, Postoperative Recovery
- Trial name
- NCT06967675
- Testing
- Low-Flow Anesthesia (LFA)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istinye University
Major Abdominal Surgeries
Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions
This study investigates the effects of low-flow desflurane anesthesia in adult patients undergoing major abdominal surgery. The researchers will examine whether different low-flow strategies: Cause differences in the Bispectral…
- Trial name
- NCT07212543
- Testing
- Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Dolunay ARIK
Atelectasis; Due to Anesthesia, General Anesthesia
Effects of Different Flow Anesthesia on Atelectasis
Evaluation of atelectasis that may be caused by different flow rate anesthesia applications during the operation with lung ultrasound score.
- Conditions
- Atelectasis; Due to Anesthesia, General Anesthesia, Low- Flow Anesthesia, Minimal Flow Anesthesia
- Trial name
- NCT05381701
- Testing
- Lung Ultrasound Score
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Humidity, Temperature
Temperature and Humidity Among Different Anesthesia Work-station
The effects of preserving humidity and temperature by low flow anesthesia are different in each other anesthesia workstation.
- Trial name
- humidity (NCT01193465)
- Testing
- Datex Ohmeda excel anesthesia machine, Datex Ohmeda Avance anesthesia work-station, Drager Cato anesthesia work-station
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Korea University Anam Hospital