Clinical trials: Low Tidal Volume Ventilation
Low Tidal Volume Ventilation, Acute Respiratory Distress Syndrome
Pulmonary Vascular Effects of Respiratory Rate & Carbon Dioxide
The purpose of this protocol is to perform serial physiological measurements and blood testing on mechanically ventilated patients comparing conditions of eucapnia and hypercapnia in the same patient.
- Trial name
- NCT01927237
- Testing
- HLR, EHR
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Mechanically Ventilated Patients, Normal Lungs
High Tidal Volume Induces Inflammation In Normal Lungs
Objective: To compare the effects of a protective versus a conventional ventilatory strategy, on systemic and in lung production of tumor necrosis factor-alpha (TNF-alpha) and interleukin-8 (IL-8) in patients without lung…
- Trial name
- Normallung (NCT00935896)
- Testing
- Low tidal volume
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Rio Grande do Sul
Postoperative Complications
The Effect of Continuous Low Tidal Volume Ventilation During Cardiopulmonary Bypass on Renal Resistive Index
Postoperative acute kidney injury following cardiopulmonary bypass surgery represents a significant barrier to patient recovery and is closely associated with increased postoperative morbidity and mortality.
- Trial name
- NCT07044102
- Testing
- Patients Undergoing Low Tidal Volume Ventilation During CABG, Patients Undergoing Apneic Ventilation During CABG
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Acute Respiratory Distress Syndrome
Airway Pressure Release Ventilation for Moderate-to-severe Acute Respiratory Distress Syndrome
This study will examine the feasibility of a large clinical trial investigating the effectiveness of airway pressure release ventilation and low tidal volume ventilation for patients with moderate-to-severe acute respiratory…
- Trial name
- EARL (NCT04156438)
- Testing
- Low tidal volume ventilation, Airway pressure release ventilation
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Mechanical Ventilation, Abdominal Surgery
Power Dissipation in Flow-controlled Ventilation
The goal of this randomized clinical cross-over trial is to compare power dissipation (Pd) during flow-controlled ventilation with either standard of low tidal volume ventilation or compliance guided individualization of…
- Trial name
- POWER-FLOW (NCT06222463)
- Testing
- Evone
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University Innsbruck
Respiration, Artificial, Acute Hypoxemic Respiratory Failure
Adherence to Low Tidal Volume in the Transition to Spontaneous Ventilation in Patients With Acute Respiratory Failure
The goal of this observational study is to estimate the prevalence of the use of protective ventilation with low tidal volume ventilation in the transition of spontaneous ventilation modes in patients with hypoxemic acute…
- Conditions
- Respiration, Artificial, Acute Hypoxemic Respiratory Failure, Respiratory Insufficiency
- Trial name
- SPIRAL (NCT06042036)
- Testing
- Spontaneous mode of mechanical ventilation
- Where
- 10 sites in Argentina, Bolivia and 8 more
- Volunteers
- 431 people
- Sponsor
- University of Sao Paulo General Hospital
Pulmonary Atelectasis
Ventilation During Cardiopulmonary Bypass (CPB) for Cardiac Surgery
During most types of heart surgery cardiopulmonary bypass (CPB) is used. CPB enables blood to be directed away from the heart and the lungs and pumped through the body while the heart is not beating.
- Trial name
- NCT02070445
- Where
- Canada
- Sponsor
- McMaster University
Atrial Fibrillation (AF), Cardiac Arrhythmias
Anesthetic Safety of High-Frequency, Very-Low Tidal Volume Ventilation With Controlled Peak Pressure During Atrial Fibrillation Ablation
This prospective, observational, within-subject crossover pilot study evaluates the impact of a high-frequency, very-low tidal volume ventilation strategy with controlled peak inspiratory pressure (HFvLTV-cPP) on…
- Trial name
- HFvLTVcPPSAFE (NCT07402798)
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Centro Medico Teknon
Acute Respiratory Distress Syndrome (ARDS)
Trial of an Alternate Mode of Providing Artificial Breaths to Children With Very Severe Pneumonia
This study attempts to study a new ventilation mode in children with Acute respiratory distress syndrome (ARDS). Despite decades of research, no intervention has brought about a significant decrease in ARDS mortality.
- Trial name
- APRiCE (NCT02167698)
- Testing
- Airway Pressure Release Ventilation (APRV), Low-tidal volume ventilation, Methylprednisolone
- Where
- India
- Volunteers
- 52 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Coronary Artery Disease
Effect of Ultra-Low Tidal Volume on Mechanical Power During Heart Bypass Surgery
The goal of this clinical trial is to evaluate whether ultra-low tidal volume (ULTV) ventilation during cardiopulmonary bypass (CPB) can reduce mechanical power (MP) and improve postoperative respiratory outcomes in adult…
- Trial name
- NCT07073885
- Testing
- Ultra-Low Tidal Volume Ventilation, Apnea Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital